[Term]
id: PR:Q5ZK92-2
name: spastin isoform 2 (chicken)
def: "A spastin (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5ZK92-2." [PRO:DNx, UniProtKB:Q5ZK92]
comment: Category=organism-sequence.
synonym: "chick-SPAST/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5ZK92-2
is_a: PR:Q5ZK92 ! spastin (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q9QYY8-1
name: spastin isoform m1 (mouse)
def: "A spastin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QYY8-1." [PMID:16026783, PRO:HJD, UniProtKB:Q9QYY8]
comment: Category=organism-sequence.
synonym: "mSPAST/iso:m1" EXACT PRO-short-label [PRO:DNx]
synonym: "spastin isoform M1 (mouse)" EXACT [UniProtKB:Q9QYY8]
synonym: "spastin isoform 68 kDa (mouse)" EXACT [UniProtKB:Q9QYY8]
xref: UniProtKB:Q9QYY8-1
is_a: PR:Q9QYY8 ! spastin (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6NW58
name: spastin (zebrafish)
def: "A spastin that is encoded in the genome of zebrafish." [OMA:Q6NW58, PANTHER:PTHR23074:SF15, PRO:DNx]
comment: Category=organism-gene.
synonym: "spg4" RELATED Gene-based [UniProtKB:Q6NW58]
synonym: "spast" RELATED Gene-based [UniProtKB:Q6NW58]
synonym: "z-SPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:85952" RELATED Gene-based [UniProtKB:Q6NW58]
synonym: "si:ch73-233a22.3" RELATED Gene-based [UniProtKB:Q6NW58]
xref: UniProtKB:Q6NW58
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template ZFIN:ZDB-GENE-040426-2331 ! spast (zebrafish)

[Term]
id: PR:Q5ZK92-1
name: spastin isoform 1 (chicken)
def: "A spastin (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5ZK92-1." [PRO:DNx, UniProtKB:Q5ZK92]
comment: Category=organism-sequence.
synonym: "chick-SPAST/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5ZK92-1
is_a: PR:Q5ZK92 ! spastin (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q9UBP0-3
name: spastin isoform h3 (human)
def: "A spastin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBP0-3." [PRO:DNx, UniProtKB:Q9UBP0]
comment: Category=organism-sequence.
synonym: "hSPAST/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "spastin isoform M87 (human)" EXACT [UniProtKB:Q9UBP0]
synonym: "spastin isoform Short (human)" EXACT [UniProtKB:Q9UBP0]
synonym: "spastin isoform 60 kDa (human)" EXACT [UniProtKB:Q9UBP0]
synonym: "spastin isoform Short variant 1 (human)" EXACT [UniProtKB:Q9UBP0]
xref: UniProtKB:Q9UBP0-3
is_a: PR:Q9UBP0 ! spastin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UBP0-2
name: spastin isoform h2 (human)
def: "A spastin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBP0-2." [PRO:DNx, UniProtKB:Q9UBP0]
comment: Category=organism-sequence.
synonym: "hSPAST/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "spastin isoform Long variant 2 (human)" EXACT [UniProtKB:Q9UBP0]
xref: UniProtKB:Q9UBP0-2
is_a: PR:Q9UBP0 ! spastin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UBP0-1
name: spastin isoform h1 (human)
def: "A spastin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBP0-1." [PRO:DNx, UniProtKB:Q9UBP0]
comment: Category=organism-sequence.
synonym: "hSPAST/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "spastin isoform M1 (human)" EXACT [UniProtKB:Q9UBP0]
synonym: "spastin isoform Long (human)" EXACT [UniProtKB:Q9UBP0]
synonym: "spastin isoform 68 kDa (human)" EXACT [UniProtKB:Q9UBP0]
synonym: "spastin isoform Long variant 1 (human)" EXACT [UniProtKB:Q9UBP0]
xref: UniProtKB:Q9UBP0-1
is_a: PR:Q9UBP0 ! spastin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:B2RYN7
name: spastin (rat)
def: "A spastin that is encoded in the genome of rat." [OMA:B2RYN7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Spg4" RELATED Gene-based [UniProtKB:B2RYN7]
synonym: "Spast" RELATED Gene-based [UniProtKB:B2RYN7]
synonym: "rSPAST" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2RYN7
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template RGD:1308494 ! Spast (rat)

[Term]
id: PR:Q5ZK92
name: spastin (chicken)
def: "A spastin that is encoded in the genome of chicken." [OMA:Q5ZK92, PANTHER:PTHR23074:SF15, PRO:DNx]
comment: Category=organism-gene.
synonym: "SPG4" RELATED Gene-based [UniProtKB:Q5ZK92]
synonym: "SPAST" RELATED Gene-based [UniProtKB:Q5ZK92]
synonym: "chick-SPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_12e12" RELATED Gene-based [UniProtKB:Q5ZK92]
xref: UniProtKB:Q5ZK92
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template NCBIGene:421481 ! SPAST (chicken)

[Term]
id: PR:000015477
name: spastin
def: "A protein that is a translation product of the human SPAST gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FSP2" RELATED Gene-based []
synonym: "SPG4" RELATED Gene-based []
synonym: "ADPSP" RELATED Gene-based []
synonym: "SPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1083" RELATED Gene-based []
synonym: "spastic paraplegia 4 protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9UBP0
name: spastin (human)
def: "A spastin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBP0]
comment: Category=organism-gene.
synonym: "FSP2" RELATED Gene-based [UniProtKB:Q9UBP0]
synonym: "SPG4" RELATED Gene-based [UniProtKB:Q9UBP0]
synonym: "ADPSP" RELATED Gene-based [UniProtKB:Q9UBP0]
synonym: "SPAST" RELATED Gene-based [UniProtKB:Q9UBP0]
synonym: "hSPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1083" RELATED Gene-based [UniProtKB:Q9UBP0]
synonym: "spastic paraplegia 4 protein (human)" EXACT [UniProtKB:Q9UBP0]
xref: UniProtKB:Q9UBP0
xref: Reactome:R-HSA-9668426 "PR:Q9UBP0 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template HGNC:11233 ! SPAST (human)

[Term]
id: PR:Q54KQ7
name: spastin (Dictyostelium discoideum)
def: "A spastin that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR23074:SF15, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-SPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0287165" RELATED Gene-based [UniProtKB:Q54KQ7]
xref: UniProtKB:Q54KQ7
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template dictyBase:DDB_G0287165 ! DDB_G0287165 (Dictyostelium discoideum)

[Term]
id: PR:Q9QYY8
name: spastin (mouse)
def: "A spastin that is encoded in the genome of mouse." [OMA:Q9QYY8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Spg4" RELATED Gene-based [UniProtKB:Q9QYY8]
synonym: "Spast" RELATED Gene-based [UniProtKB:Q9QYY8]
synonym: "mSPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa1083" RELATED Gene-based [UniProtKB:Q9QYY8]
xref: UniProtKB:Q9QYY8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template MGI:1858896 ! Spast (mouse)

[Term]
id: PR:Q9UBP0-4
name: spastin isoform h4 (human)
def: "A spastin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBP0-4." [PRO:DNx, UniProtKB:Q9UBP0]
comment: Category=organism-sequence.
synonym: "hSPAST/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "spastin isoform Short variant 2 (human)" EXACT [UniProtKB:Q9UBP0]
xref: UniProtKB:Q9UBP0-4
is_a: PR:Q9UBP0 ! spastin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8I0P1
name: spastin (fruit fly)
def: "A spastin that is encoded in the genome of fruit fly." [OMA:Q8I0P1, PANTHER:PTHR23074:SF15, PRO:DNx]
comment: Category=organism-gene.
synonym: "spas" RELATED Gene-based [UniProtKB:Q8I0P1]
synonym: "CG5977" RELATED Gene-based [UniProtKB:Q8I0P1]
synonym: "D-Spastin" EXACT [UniProtKB:Q8I0P1]
synonym: "fly-SPAST" EXACT PRO-short-label [PRO:DNx]
synonym: "Dm-Spastin" EXACT [UniProtKB:Q8I0P1]
synonym: "dspastin (fruit fly)" EXACT [UniProtKB:Q8I0P1]
xref: UniProtKB:Q8I0P1
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000015477 ! spastin
relationship: has_gene_template FlyBase:FBgn0039141 ! spas (fruit fly)

[Term]
id: PR:Q9QYY8-2
name: spastin isoform m2 (mouse)
def: "A spastin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9QYY8-2." [PMID:16026783, PRO:HJD, UniProtKB:Q9QYY8]
comment: Category=organism-sequence.
synonym: "mSPAST/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "spastin isoform M87 (mouse)" EXACT [UniProtKB:Q9QYY8]
synonym: "spastin isoform Short (mouse)" EXACT [UniProtKB:Q9QYY8]
synonym: "spastin isoform 60 kDa (mouse)" EXACT [UniProtKB:Q9QYY8]
synonym: "spastin isoform Short variant 1 (mouse)" EXACT [UniProtKB:Q9QYY8]
xref: UniProtKB:Q9QYY8-2
is_a: PR:Q9QYY8 ! spastin (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus