[Term]
id: PR:000049323
name: sclerostin, signal peptide removed form (human)
def: "A sclerostin (human) that has had the signal peptide removed. UniProtKB:Q9BQB4, 24-213." [PRO:DNx, Reactome:R-HSA-3769322]
comment: Category=organism-modification.
synonym: "hSOST/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000033177" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q9BQB4, 24-213" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3769322 "PR:000049323 located_in GO:0005576"
intersection_of: PR:Q9BQB4 ! sclerostin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BQB4-1
name: sclerostin isoform h1 (human)
def: "A sclerostin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQB4-1." [PRO:DNx, UniProtKB:Q9BQB4]
comment: Category=organism-sequence.
synonym: "hSOST/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQB4-1
is_a: PR:Q9BQB4 ! sclerostin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000015415
name: sclerostin
def: "A protein that is a translation product of the human SOST gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SOST" EXACT PRO-short-label [PRO:DNx]
synonym: "UNQ2976/PRO7455/PRO7476" RELATED Gene-based []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9BQB4
name: sclerostin (human)
def: "A sclerostin that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BQB4]
comment: Category=organism-gene.
synonym: "SOST" RELATED Gene-based [UniProtKB:Q9BQB4]
synonym: "hSOST" EXACT PRO-short-label [PRO:DNx]
synonym: "UNQ2976/PRO7455/PRO7476" RELATED Gene-based [UniProtKB:Q9BQB4]
xref: UniProtKB:Q9BQB4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015415 ! sclerostin
relationship: has_gene_template HGNC:13771 ! SOST (human)

[Term]
id: PR:Q9BQB4-2
name: sclerostin isoform h2 (human)
def: "A sclerostin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQB4-2." [PRO:DNx, UniProtKB:Q9BQB4]
comment: Category=organism-sequence.
synonym: "hSOST/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQB4-2
is_a: PR:Q9BQB4 ! sclerostin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens