[Term]
id: PR:P31639-1
name: sodium/glucose cotransporter 2 isoform h1 (human)
def: "A sodium/glucose cotransporter 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31639-1." [PRO:DNx, UniProtKB:P31639]
comment: Category=organism-sequence.
synonym: "hSLC5A2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P31639-1
is_a: PR:P31639 ! sodium/glucose cotransporter 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31639-2
name: sodium/glucose cotransporter 2 isoform h2 (human)
def: "A sodium/glucose cotransporter 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31639-2." [PRO:DNx, UniProtKB:P31639]
comment: Category=organism-sequence.
synonym: "hSLC5A2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P31639-2
is_a: PR:P31639 ! sodium/glucose cotransporter 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31639
name: sodium/glucose cotransporter 2 (human)
def: "A sodium/glucose cotransporter 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P31639]
comment: Category=organism-gene.
synonym: "SGLT2" RELATED Gene-based [UniProtKB:P31639]
synonym: "SLC5A2" RELATED Gene-based [UniProtKB:P31639]
synonym: "hSLC5A2" EXACT PRO-short-label [PRO:DNx]
synonym: "Na(+)/glucose cotransporter 2 (human)" EXACT [UniProtKB:P31639]
synonym: "solute carrier family 5 member 2 (human)" EXACT [UniProtKB:P31639]
synonym: "low affinity sodium-glucose cotransporter (human)" EXACT [UniProtKB:P31639]
xref: Reactome:R-HSA-429568 "PR:P31639 located_in GO:0005886"
xref: UniProtKB:P31639
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015169 ! sodium/glucose cotransporter 2
relationship: has_gene_template HGNC:11037 ! SLC5A2 (human)

[Term]
id: PR:000015169
name: sodium/glucose cotransporter 2
def: "A protein that is a translation product of the human SLC5A2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SGLT2" RELATED Gene-based []
synonym: "SLC5A2" EXACT PRO-short-label [PRO:DNx]
synonym: "Na(+)/glucose cotransporter 2" EXACT []
synonym: "solute carrier family 5 member 2" EXACT []
synonym: "low affinity sodium-glucose cotransporter" RELATED []
xref: IUPHARobj:916
is_a: PR:000000001 ! protein

[Term]
id: PR:000056372
name: sodium/glucose cotransporter 2 O-glycosylated 1 (human)
def: "A sodium/glucose cotransporter 2 (human) that has been O-glycosylated at the residue equivalent to Thr-5 of the amino acid sequence represented by UniProtKB:P31639-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P31639-1, Thr-5, MOD:00005~GNO:G43417UB." [GlyGen:P31639-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSLC5A2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P31639-1, Thr-5, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P31639 ! sodium/glucose cotransporter 2 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens