[Term]
id: PR:Q13309
name: S-phase kinase-associated protein 2 (human)
def: "An S-phase kinase-associated protein 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "SKP2" RELATED Gene-based [UniProtKB:Q13309]
synonym: "FBXL1" RELATED Gene-based [UniProtKB:Q13309]
synonym: "hSKP2" EXACT PRO-short-label [PRO:DNx]
synonym: "p45skp2 (human)" EXACT [UniProtKB:Q13309]
synonym: "F-box protein Skp2 (human)" EXACT [UniProtKB:Q13309]
synonym: "F-box/LRR-repeat protein 1 (human)" EXACT [UniProtKB:Q13309]
synonym: "cyclin-A/CDK2-associated protein p45 (human)" EXACT [UniProtKB:Q13309]
xref: Reactome:R-HSA-975495 "PR:Q13309 located_in GO:0005829"
xref: Reactome:R-HSA-975554 "PR:Q13309 located_in GO:0005654"
xref: UniProtKB:Q13309
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014909 ! S-phase kinase-associated protein 2
relationship: has_gene_template HGNC:10901 ! SKP2 (human)

[Term]
id: PR:000014909
name: S-phase kinase-associated protein 2
def: "A protein that is a translation product of the human SKP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FWD1" EXACT []
synonym: "SKP2" EXACT PRO-short-label [PRO:DNx]
synonym: "FBXL1" RELATED Gene-based []
synonym: "p45skp2" EXACT []
synonym: "F-box protein Skp2" EXACT []
synonym: "F-box/WD-40 protein 1" EXACT []
synonym: "F-box/LRR-repeat protein 1" EXACT []
synonym: "cyclin-A/CDK2-associated protein p45" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13309-1
name: S-phase kinase-associated protein 2 isoform 1 (human)
def: "An S-phase kinase-associated protein 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSKP2/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "S-phase kinase-associated protein 2 isoform SKP2-alpha (human)" EXACT [UniProtKB:Q13309]
xref: UniProtKB:Q13309-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040412 ! S-phase kinase-associated protein 2 isoform 1

[Term]
id: PR:000045908
name: S-phase kinase-associated protein 2 phosphorylated 1 (human)
def: "An S-phase kinase-associated protein 2 (human) that has been phosphorylated at the position equivalent to Ser-72 of the amino acid sequence represented by UniProtKB:Q13309-1. Example: UniProtKB:Q13309-1, Ser-72, MOD:00046." [PMID:19270695, iPTMnet:Q13309]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19270695). Status=unreviewed.
synonym: "hSKP2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13309-1, Ser-72, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13309 ! S-phase kinase-associated protein 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13309-2
name: S-phase kinase-associated protein 2 isoform h2 (human)
def: "An S-phase kinase-associated protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13309-2." [PRO:DNx, UniProtKB:Q13309]
comment: Category=organism-sequence.
synonym: "hSKP2/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "S-phase kinase-associated protein 2 isoform SKP2-beta (human)" EXACT [UniProtKB:Q13309]
xref: UniProtKB:Q13309-2
is_a: PR:Q13309 ! S-phase kinase-associated protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13309-4
name: S-phase kinase-associated protein 2 isoform h3 (human)
def: "An S-phase kinase-associated protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13309-4." [PRO:DNx, UniProtKB:Q13309]
comment: Category=organism-sequence.
synonym: "hSKP2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13309-4
is_a: PR:Q13309 ! S-phase kinase-associated protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens