[Term]
id: PR:Q8VDQ8-2
name: NAD-dependent protein deacetylase sirtuin-2 isoform m2 (mouse)
def: "An NAD-dependent protein deacetylase sirtuin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VDQ8-2." [PRO:DNx, UniProtKB:Q8VDQ8]
comment: Category=organism-sequence.
synonym: "mSIRT2/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "NAD-dependent protein deacetylase sirtuin-2 isoform SIRT2.2 (mouse)" EXACT [UniProtKB:Q8VDQ8]
xref: UniProtKB:Q8VDQ8-2
is_a: PR:Q8VDQ8 ! NAD-dependent protein deacetylase sirtuin-2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8IXJ6-1
name: NAD-dependent protein deacetylase sirtuin-2 isoform 1 (human)
def: "An NAD-dependent protein deacetylase sirtuin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSIRT2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IXJ6-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000041728 ! NAD-dependent protein deacetylase sirtuin-2 isoform 1

[Term]
id: PR:Q8IXJ6-2
name: NAD-dependent protein deacetylase sirtuin-2 isoform h2 (human)
def: "An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-2." [PRO:DNx, UniProtKB:Q8IXJ6]
comment: Category=organism-sequence.
synonym: "hSIRT2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IXJ6-2
is_a: PR:Q8IXJ6 ! NAD-dependent protein deacetylase sirtuin-2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IXJ6-3
name: NAD-dependent protein deacetylase sirtuin-2 isoform h3 (human)
def: "An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-3." [PRO:DNx, UniProtKB:Q8IXJ6]
comment: Category=organism-sequence.
synonym: "hSIRT2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IXJ6-3
is_a: PR:Q8IXJ6 ! NAD-dependent protein deacetylase sirtuin-2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IXJ6-4
name: NAD-dependent protein deacetylase sirtuin-2 isoform h4 (human)
def: "An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-4." [PRO:DNx, UniProtKB:Q8IXJ6]
comment: Category=organism-sequence.
synonym: "hSIRT2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IXJ6-4
is_a: PR:Q8IXJ6 ! NAD-dependent protein deacetylase sirtuin-2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IXJ6
name: NAD-dependent protein deacetylase sirtuin-2 (human)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IXJ6]
comment: Category=organism-gene.
synonym: "SIR2L" RELATED Gene-based [UniProtKB:Q8IXJ6]
synonym: "SIRT2" RELATED Gene-based [UniProtKB:Q8IXJ6]
synonym: "SIR2L2" RELATED Gene-based [UniProtKB:Q8IXJ6]
synonym: "hSIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "SIR2-like protein 2 (human)" EXACT [UniProtKB:Q8IXJ6]
synonym: "regulatory protein SIR2 homolog 2 (human)" EXACT [UniProtKB:Q8IXJ6]
xref: UniProtKB:Q8IXJ6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template HGNC:10886 ! SIRT2 (human)

[Term]
id: PR:Q8VDQ8-1
name: NAD-dependent protein deacetylase sirtuin-2 isoform 1 (mouse)
def: "An NAD-dependent protein deacetylase sirtuin-2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mSIRT2/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "NAD-dependent protein deacetylase sirtuin-2 isoform SIRT2.1 (mouse)" EXACT [UniProtKB:Q8VDQ8]
xref: UniProtKB:Q8VDQ8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000041728 ! NAD-dependent protein deacetylase sirtuin-2 isoform 1

[Term]
id: PR:Q8VDQ8-3
name: NAD-dependent protein deacetylase sirtuin-2 isoform m3 (mouse)
def: "An NAD-dependent protein deacetylase sirtuin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VDQ8-3." [PRO:DNx, UniProtKB:Q8VDQ8]
comment: Category=organism-sequence.
synonym: "mSIRT2/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8VDQ8-3
is_a: PR:Q8VDQ8 ! NAD-dependent protein deacetylase sirtuin-2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000014889
name: NAD-dependent protein deacetylase sirtuin-2
def: "A protein that is a translation product of the human SIRT2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SIR2L" RELATED Gene-based []
synonym: "SIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "SIR2L2" RELATED Gene-based []
synonym: "SIR2-like protein 2" EXACT []
synonym: "regulatory protein SIR2 homolog 2" EXACT []
synonym: "NAD-dependent deacetylase sirtuin-2" EXACT []
xref: IUPHARobj:2708
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9I7I7
name: NAD-dependent protein deacetylase Sirt2 (fruit fly)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of fruit fly." [OMA:Q9I7I7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Sirt2" RELATED Gene-based [UniProtKB:Q9I7I7]
synonym: "CG5085" RELATED Gene-based [UniProtKB:Q9I7I7]
synonym: "fly-SIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "SIR2-related protein (fruit fly)" EXACT [UniProtKB:Q9I7I7]
synonym: "regulatory protein SIR2 homolog (fruit fly)" EXACT [UniProtKB:Q9I7I7]
xref: UniProtKB:Q9I7I7
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template FlyBase:FBgn0038788 ! Sirt2 (fruit fly)

[Term]
id: PR:000041728
name: NAD-dependent protein deacetylase sirtuin-2 isoform 1
def: "An NAD-dependent protein deacetylase sirtuin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "SIRT2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2

[Term]
id: PR:000021481
name: NAD-dependent protein deacetylase sirtuin-2, initiator methionine removed form
def: "An NAD-dependent protein deacetylase sirtuin-2 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "SIRT2/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q8VDQ8
name: NAD-dependent protein deacetylase sirtuin-2 (mouse)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of mouse." [OMA:Q8VDQ8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Sirt2" RELATED Gene-based [UniProtKB:Q8VDQ8]
synonym: "Sir2l2" RELATED Gene-based [UniProtKB:Q8VDQ8]
synonym: "mSIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "mSIR2L2" EXACT [UniProtKB:Q8VDQ8]
synonym: "SIR2-like protein 2 (mouse)" EXACT [UniProtKB:Q8VDQ8]
synonym: "regulatory protein SIR2 homolog 2 (mouse)" EXACT [UniProtKB:Q8VDQ8]
xref: UniProtKB:Q8VDQ8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template MGI:1927664 ! Sirt2 (mouse)

[Term]
id: PR:Q54QE6
name: NAD-dependent deacetylase sir2A (Dictyostelium discoideum)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]
comment: Category=organism-gene.
synonym: "sir2A" RELATED Gene-based [UniProtKB:Q54QE6]
synonym: "Dicty-SIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0283917" RELATED Gene-based [UniProtKB:Q54QE6]
synonym: "silent information regulator sir2A (Dictyostelium discoideum)" EXACT [UniProtKB:Q54QE6]
xref: UniProtKB:Q54QE6
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template dictyBase:DDB_G0283917 ! sir2A (Dictyostelium discoideum)

[Term]
id: PR:P53686
name: NAD-dependent protein deacetylase HST2 (yeast)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of yeast." [PRO:DNx]
comment: Category=organism-gene.
synonym: "HST2" RELATED Gene-based [UniProtKB:P53686]
synonym: "LPA2C" RELATED Gene-based [UniProtKB:P53686]
synonym: "ySIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "YPL015C" RELATED Gene-based [UniProtKB:P53686]
synonym: "homologous to SIR2 protein 2 (yeast)" EXACT [UniProtKB:P53686]
synonym: "regulatory protein SIR2 homolog 2 (yeast)" EXACT [UniProtKB:P53686]
xref: UniProtKB:P53686
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template SGD:S000005936 ! HST2 (yeast)

[Term]
id: PR:Q9USN7
name: NAD-dependent protein deacetylase hst2 (Schizosaccharomyces pombe 972h-)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]
comment: Category=organism-gene.
synonym: "hst2" RELATED Gene-based [UniProtKB:Q9USN7]
synonym: "SPCC132.02" RELATED Gene-based [UniProtKB:Q9USN7]
synonym: "Spom972h-SIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "homologous to sir2 protein 2 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9USN7]
synonym: "regulatory protein SIR2 homolog 2 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9USN7]
xref: UniProtKB:Q9USN7
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template PomBase:SPCC132.02 ! hst2 (Schizosaccharomyces pombe)

[Term]
id: PR:Q7ZVK3
name: NAD-dependent protein deacetylase sirtuin-2 (zebrafish)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of zebrafish." [OMA:Q7ZVK3, PRO:DNx]
comment: Category=organism-gene.
synonym: "sirt2" RELATED Gene-based [UniProtKB:Q7ZVK3]
synonym: "z-SIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:77003" RELATED Gene-based [UniProtKB:Q7ZVK3]
synonym: "SIR2-like protein 2 (zebrafish)" EXACT [UniProtKB:Q7ZVK3]
synonym: "regulatory protein SIR2 homolog 2 (zebrafish)" EXACT [UniProtKB:Q7ZVK3]
xref: UniProtKB:Q7ZVK3
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template ZFIN:ZDB-GENE-030131-1028 ! sirt2 (zebrafish)

[Term]
id: PR:Q5RJQ4
name: NAD-dependent protein deacetylase sirtuin-2 (rat)
def: "An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Sirt2" RELATED Gene-based [UniProtKB:Q5RJQ4]
synonym: "Sir2l2" RELATED Gene-based [UniProtKB:Q5RJQ4]
synonym: "rSIRT2" EXACT PRO-short-label [PRO:DNx]
synonym: "SIR2-like protein 2 (rat)" EXACT [UniProtKB:Q5RJQ4]
synonym: "regulatory protein SIR2 homolog 2 (rat)" EXACT [UniProtKB:Q5RJQ4]
xref: UniProtKB:Q5RJQ4
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000014889 ! NAD-dependent protein deacetylase sirtuin-2
relationship: has_gene_template RGD:621481 ! Sirt2 (rat)

[Term]
id: PR:Q8VDQ8-4
name: NAD-dependent protein deacetylase sirtuin-2 isoform m4 (mouse)
def: "An NAD-dependent protein deacetylase sirtuin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8VDQ8-4." [PRO:DNx, UniProtKB:Q8VDQ8]
comment: Category=organism-sequence.
synonym: "mSIRT2/iso:m4" EXACT PRO-short-label [PRO:DNx]
synonym: "NAD-dependent protein deacetylase sirtuin-2 isoform SIRT2.3 (mouse)" EXACT [UniProtKB:Q8VDQ8]
xref: UniProtKB:Q8VDQ8-4
is_a: PR:Q8VDQ8 ! NAD-dependent protein deacetylase sirtuin-2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8IXJ6-5
name: NAD-dependent protein deacetylase sirtuin-2 isoform h5 (human)
def: "An NAD-dependent protein deacetylase sirtuin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IXJ6-5." [PRO:DNx, UniProtKB:Q8IXJ6]
comment: Category=organism-sequence.
synonym: "hSIRT2/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IXJ6-5
is_a: PR:Q8IXJ6 ! NAD-dependent protein deacetylase sirtuin-2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens