[Term]
id: PR:Q94JQ3
name: serine hydroxymethyltransferase 3, chloroplastic (Arabidopsis thaliana)
def: "A serine hydroxymethyltransferase, mitochondrial that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]
comment: Category=organism-gene.
synonym: "SHM3" RELATED Gene-based [UniProtKB:Q94JQ3]
synonym: "SHMT3" RELATED Gene-based [UniProtKB:Q94JQ3]
synonym: "AtSHM3" EXACT [UniProtKB:Q94JQ3]
synonym: "AtSHMT3" RELATED Gene-based [UniProtKB:Q94JQ3]
synonym: "At-SHMT2" EXACT PRO-short-label [PRO:DNx]
synonym: "F8B4.220" RELATED Gene-based [UniProtKB:Q94JQ3]
synonym: "At4g32520" RELATED Gene-based [UniProtKB:Q94JQ3]
synonym: "serine methylase 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q94JQ3]
synonym: "glycine hydroxymethyltransferase 3 (Arabidopsis thaliana)" EXACT [UniProtKB:Q94JQ3]
xref: UniProtKB:Q94JQ3
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000014848 ! serine hydroxymethyltransferase, mitochondrial
relationship: has_gene_template Araport:AT4G32520 ! SHM3 (Arabidopsis thaliana)

[Term]
id: PR:Q9CZN7
name: serine hydroxymethyltransferase, mitochondrial (mouse)
def: "A serine hydroxymethyltransferase, mitochondrial that is encoded in the genome of mouse." [OMA:Q9CZN7, PANTHER:PTHR11680:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Shmt2" RELATED Gene-based [UniProtKB:Q9CZN7]
synonym: "mSHMT2" EXACT PRO-short-label [PRO:DNx]
synonym: "SHMT (mouse)" RELATED [UniProtKB:Q9CZN7]
synonym: "serine methylase (mouse)" RELATED [UniProtKB:Q9CZN7]
synonym: "glycine hydroxymethyltransferase (mouse)" RELATED [UniProtKB:Q9CZN7]
xref: UniProtKB:Q9CZN7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014848 ! serine hydroxymethyltransferase, mitochondrial
relationship: has_gene_template MGI:1277989 ! Shmt2 (mouse)

[Term]
id: PR:P34897
name: serine hydroxymethyltransferase, mitochondrial (human)
def: "A serine hydroxymethyltransferase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P34897]
comment: Category=organism-gene.
synonym: "SHMT2" RELATED Gene-based [UniProtKB:P34897]
synonym: "hSHMT2" EXACT PRO-short-label [PRO:DNx]
synonym: "SHMT (human)" BROAD [UniProtKB:P34897]
synonym: "serine methylase (human)" BROAD [UniProtKB:P34897]
synonym: "glycine hydroxymethyltransferase (human)" BROAD [UniProtKB:P34897]
xref: UniProtKB:P34897
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014848 ! serine hydroxymethyltransferase, mitochondrial
relationship: has_gene_template HGNC:10852 ! SHMT2 (human)

[Term]
id: PR:P34897-3
name: serine hydroxymethyltransferase, mitochondrial isoform h3 (human)
def: "A serine hydroxymethyltransferase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34897-3." [PRO:DNx, UniProtKB:P34897]
comment: Category=organism-sequence.
synonym: "hSHMT2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34897-3
is_a: PR:P34897 ! serine hydroxymethyltransferase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P34897-2
name: serine hydroxymethyltransferase, mitochondrial isoform h2 (human)
def: "A serine hydroxymethyltransferase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34897-2." [PRO:DNx, UniProtKB:P34897]
comment: Category=organism-sequence.
synonym: "hSHMT2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34897-2
is_a: PR:P34897 ! serine hydroxymethyltransferase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P34897-1
name: serine hydroxymethyltransferase, mitochondrial isoform h1 (human)
def: "A serine hydroxymethyltransferase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34897-1." [PRO:DNx, UniProtKB:P34897]
comment: Category=organism-sequence.
synonym: "hSHMT2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34897-1
is_a: PR:P34897 ! serine hydroxymethyltransferase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049237
name: serine hydroxymethyltransferase, mitochondrial, transit peptide removed form (human)
def: "A serine hydroxymethyltransferase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P34897, 30-504." [PRO:DNx, Reactome:R-HSA-5694086]
comment: Category=organism-modification.
synonym: "PRO_0000032562" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hSHMT2/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P34897, 30-504" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5694086 "PR:000049237 located_in GO:0005743"
intersection_of: PR:P34897 ! serine hydroxymethyltransferase, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9CZN7-1
name: serine hydroxymethyltransferase, mitochondrial isoform m1 (mouse)
def: "A serine hydroxymethyltransferase, mitochondrial (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CZN7-1." [PRO:DNx, UniProtKB:Q9CZN7]
comment: Category=organism-sequence.
synonym: "mSHMT2/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9CZN7-1
is_a: PR:Q9CZN7 ! serine hydroxymethyltransferase, mitochondrial (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9CZN7-2
name: serine hydroxymethyltransferase, mitochondrial isoform m2 (mouse)
def: "A serine hydroxymethyltransferase, mitochondrial (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CZN7-2." [PRO:DNx, UniProtKB:Q9CZN7]
comment: Category=organism-sequence.
synonym: "mSHMT2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9CZN7-2
is_a: PR:Q9CZN7 ! serine hydroxymethyltransferase, mitochondrial (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000014848
name: serine hydroxymethyltransferase, mitochondrial
def: "A protein that is a translation product of the human SHMT2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SHMT" BROAD [PRO:DNx]
synonym: "SHMT2" EXACT PRO-short-label [PRO:DNx]
synonym: "serine methylase" BROAD [PRO:DNx]
synonym: "glycine hydroxymethyltransferase" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000021472
name: serine hydroxymethyltransferase, mitochondrial, transit peptide removed form
def: "A serine hydroxymethyltransferase, mitochondrial that has had the transit peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "SHMT2/TransPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000014848 ! serine hydroxymethyltransferase, mitochondrial
intersection_of: lacks_part SO:0000725 ! transit_peptide