[Term]
id: PR:000049227
name: SH2B adapter protein 2 phosphorylated 1 (human)
def: "An SH2B adapter protein 2 (human) that has been post-translationally modified to include phosphotyrosine at position 629 of the amino acid sequence represented by UniProtKB:O14492. UniProtKB:O14492, Tyr-629, MOD:00048." [PRO:DNx, Reactome:R-HSA-112184]
comment: Category=organism-modification.
synonym: "hSH2B2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14492, Tyr-629, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-112184 "PR:000049227 located_in GO:0005829"
is_a: PR:O14492 ! SH2B adapter protein 2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14492
name: SH2B adapter protein 2 (human)
def: "An SH2B adapter protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14492]
comment: Category=organism-gene.
synonym: "APS" RELATED Gene-based [UniProtKB:O14492]
synonym: "SH2B2" RELATED Gene-based [UniProtKB:O14492]
synonym: "hSH2B2" EXACT PRO-short-label [PRO:DNx]
synonym: "SH2 and PH domain-containing adapter protein APS (human)" EXACT [UniProtKB:O14492]
synonym: "adapter protein with pleckstrin homology and Src homology 2 domains (human)" EXACT [UniProtKB:O14492]
xref: UniProtKB:O14492
xref: Reactome:R-HSA-112195 "PR:O14492 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014810 ! SH2B adapter protein 2
relationship: has_gene_template HGNC:17381 ! SH2B2 (human)

[Term]
id: PR:000014810
name: SH2B adapter protein 2
def: "A protein that is a translation product of the human SH2B2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "APS" RELATED Gene-based []
synonym: "SH2B2" EXACT PRO-short-label [PRO:DNx]
synonym: "SH2 and PH domain-containing adapter protein APS" EXACT []
synonym: "adapter protein with pleckstrin homology and Src homology 2 domains" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O14492-1
name: SH2B adapter protein 2 isoform h1 (human)
def: "An SH2B adapter protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14492-1." [PRO:DNx, UniProtKB:O14492]
comment: Category=organism-sequence.
synonym: "hSH2B2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14492-1
is_a: PR:O14492 ! SH2B adapter protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14492-2
name: SH2B adapter protein 2 isoform h2 (human)
def: "An SH2B adapter protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14492-2." [PRO:DNx, UniProtKB:O14492]
comment: Category=organism-sequence.
synonym: "hSH2B2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14492-2
is_a: PR:O14492 ! SH2B adapter protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens