[Term] id: PR:O14492-1 name: SH2B adapter protein 2 isoform h1 (human) def: "An SH2B adapter protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14492-1." [PRO:DNx, UniProtKB:O14492] comment: Category=organism-sequence. synonym: "hSH2B2/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O14492-1 is_a: PR:O14492 ! SH2B adapter protein 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000014810 name: SH2B adapter protein 2 def: "A protein that is a translation product of the human SH2B2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "APS" RELATED Gene-based [] synonym: "SH2B2" EXACT PRO-short-label [PRO:DNx] synonym: "SH2 and PH domain-containing adapter protein APS" EXACT [] synonym: "adapter protein with pleckstrin homology and Src homology 2 domains" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:O14492-2 name: SH2B adapter protein 2 isoform h2 (human) def: "An SH2B adapter protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14492-2." [PRO:DNx, UniProtKB:O14492] comment: Category=organism-sequence. synonym: "hSH2B2/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O14492-2 is_a: PR:O14492 ! SH2B adapter protein 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9Z200-1 name: SH2B adapter protein 2 isoform 1 (rat) def: "An SH2B adapter protein 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rSH2B2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z200-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043417 ! SH2B adapter protein 2 isoform 1 [Term] id: PR:000049227 name: SH2B adapter protein 2 phosphorylated 1 (human) def: "An SH2B adapter protein 2 (human) that has been post-translationally modified to include phosphotyrosine at position 629 of the amino acid sequence represented by UniProtKB:O14492. UniProtKB:O14492, Tyr-629, MOD:00048." [PRO:DNx, Reactome:R-HSA-112184] comment: Category=organism-modification. synonym: "hSH2B2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O14492, Tyr-629, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-112184 "PR:000049227 located_in GO:0005829" is_a: PR:O14492 ! SH2B adapter protein 2 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9JID9-1 name: SH2B adapter protein 2 isoform 1 (mouse) def: "An SH2B adapter protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mSH2B2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JID9-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043417 ! SH2B adapter protein 2 isoform 1 [Term] id: PR:Q9Z200 name: SH2B adapter protein 2 (rat) def: "An SH2B adapter protein 2 that is encoded in the genome of rat." [OMA:Q9Z200, PANTHER:PTHR10872:SF4, PRO:DNx] comment: Category=organism-gene. synonym: "Aps" RELATED Gene-based [UniProtKB:Q9Z200] synonym: "Sh2b2" RELATED Gene-based [UniProtKB:Q9Z200] synonym: "rSH2B2" EXACT PRO-short-label [PRO:DNx] synonym: "SH2 and PH domain-containing adapter protein APS (rat)" EXACT [UniProtKB:Q9Z200] synonym: "adapter protein with pleckstrin homology and Src homology 2 domains (rat)" EXACT [UniProtKB:Q9Z200] xref: UniProtKB:Q9Z200 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000014810 ! SH2B adapter protein 2 relationship: has_gene_template RGD:69284 ! Sh2b2 (rat) [Term] id: PR:Q9JID9 name: SH2B adapter protein 2 (mouse) def: "An SH2B adapter protein 2 that is encoded in the genome of mouse." [OMA:Q9JID9, PRO:DNx] comment: Category=organism-gene. synonym: "Aps" RELATED Gene-based [UniProtKB:Q9JID9] synonym: "Sh2b2" RELATED Gene-based [UniProtKB:Q9JID9] synonym: "mSH2B2" EXACT PRO-short-label [PRO:DNx] synonym: "SH2 and PH domain-containing adapter protein APS (mouse)" EXACT [UniProtKB:Q9JID9] synonym: "adapter protein with pleckstrin homology and Src homology 2 domains (mouse)" EXACT [UniProtKB:Q9JID9] xref: UniProtKB:Q9JID9 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000014810 ! SH2B adapter protein 2 relationship: has_gene_template MGI:1345171 ! Sh2b2 (mouse) [Term] id: PR:O14492 name: SH2B adapter protein 2 (human) def: "An SH2B adapter protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14492] comment: Category=organism-gene. synonym: "APS" RELATED Gene-based [UniProtKB:O14492] synonym: "SH2B2" RELATED Gene-based [UniProtKB:O14492] synonym: "hSH2B2" EXACT PRO-short-label [PRO:DNx] synonym: "SH2 and PH domain-containing adapter protein APS (human)" EXACT [UniProtKB:O14492] synonym: "adapter protein with pleckstrin homology and Src homology 2 domains (human)" EXACT [UniProtKB:O14492] xref: UniProtKB:O14492 xref: Reactome:R-HSA-112195 "PR:O14492 located_in GO:0005829" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014810 ! SH2B adapter protein 2 relationship: has_gene_template HGNC:17381 ! SH2B2 (human) [Term] id: PR:000043417 name: SH2B adapter protein 2 isoform 1 def: "An SH2B adapter protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JID9-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "SH2B2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000014810 ! SH2B adapter protein 2