[Term]
id: PR:O00141-5
name: serine/threonine-protein kinase Sgk1 isoform h5 (human)
def: "A serine/threonine-protein kinase Sgk1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00141-5." [PRO:DNx, UniProtKB:O00141]
comment: Category=organism-sequence.
synonym: "hSGK1/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00141-5
is_a: PR:O00141 ! serine/threonine-protein kinase Sgk1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00141-4
name: serine/threonine-protein kinase Sgk1 isoform h4 (human)
def: "A serine/threonine-protein kinase Sgk1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00141-4." [PRO:DNx, UniProtKB:O00141]
comment: Category=organism-sequence.
synonym: "hSGK1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00141-4
is_a: PR:O00141 ! serine/threonine-protein kinase Sgk1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00141-1
name: serine/threonine-protein kinase Sgk1 isoform 1 (human)
def: "A serine/threonine-protein kinase Sgk1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSGK1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00141-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037892 ! serine/threonine-protein kinase Sgk1 isoform 1

[Term]
id: PR:O00141-3
name: serine/threonine-protein kinase Sgk1 isoform 3 (human)
def: "A serine/threonine-protein kinase Sgk1 isoform 3 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hSGK1/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase Sgk1 isoform Sgk1.2 (human)" EXACT [UniProtKB:O00141]
xref: UniProtKB:O00141-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037893 ! serine/threonine-protein kinase Sgk1 isoform 3

[Term]
id: PR:O00141-2
name: serine/threonine-protein kinase Sgk1 isoform h2 (human)
def: "A serine/threonine-protein kinase Sgk1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00141-2." [PRO:DNx, UniProtKB:O00141]
comment: Category=organism-sequence.
synonym: "hSGK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase Sgk1 isoform Sgk1.1 (human)" EXACT [UniProtKB:O00141]
synonym: "serine/threonine-protein kinase Sgk1 isoform Sgk1_v2 (human)" EXACT [UniProtKB:O00141]
xref: UniProtKB:O00141-2
is_a: PR:O00141 ! serine/threonine-protein kinase Sgk1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049223
name: serine/threonine-protein kinase Sgk1 phosphorylated 3 (human)
def: "A serine/threonine-protein kinase Sgk1 (human) that has been post-translationally modified to include phosphothreonine at position 256, and phosphoserine at position 422 of the amino acid sequence represented by UniProtKB:O00141. UniProtKB:O00141, Thr-256, MOD:00047|Ser-422, MOD:00046." [PRO:DNx, Reactome:R-HSA-6795449]
comment: Category=organism-modification.
synonym: "hSGK1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00141, Thr-256, MOD:00047|Ser-422, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6795449 "PR:000049223 located_in GO:0005829"
xref: Reactome:R-HSA-9612512 "PR:000049223 located_in GO:0005654"
is_a: PR:O00141 ! serine/threonine-protein kinase Sgk1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049222
name: serine/threonine-protein kinase Sgk1 phosphorylated 2 (human)
def: "A serine/threonine-protein kinase Sgk1 (human) that has been post-translationally modified to include phosphoserine at position 422 of the amino acid sequence represented by UniProtKB:O00141. UniProtKB:O00141, Ser-422, MOD:00046." [PRO:DNx, Reactome:R-HSA-6795313]
comment: Category=organism-modification.
synonym: "hSGK1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00141, Ser-422, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6795313 "PR:000049222 located_in GO:0005829"
is_a: PR:O00141 ! serine/threonine-protein kinase Sgk1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045554
name: serine/threonine-protein kinase Sgk1 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase Sgk1 (human) that has been phosphorylated at the position equivalent to Ser-78 of the amino acid sequence represented by UniProtKB:O00141-1. Example: UniProtKB:O00141-1, Ser-78, MOD:00046." [PMID:11254654, iPTMnet:O00141]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11254654). Status=unreviewed.
synonym: "hSGK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00141-1, Ser-78, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O00141 ! serine/threonine-protein kinase Sgk1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00141
name: serine/threonine-protein kinase Sgk1 (human)
def: "A serine/threonine-protein kinase Sgk1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00141]
comment: Category=organism-gene.
synonym: "SGK" RELATED Gene-based [UniProtKB:O00141]
synonym: "SGK1" RELATED Gene-based [UniProtKB:O00141]
synonym: "hSGK1" EXACT PRO-short-label [PRO:DNx]
synonym: "serum/glucocorticoid-regulated kinase 1 (human)" EXACT [UniProtKB:O00141]
xref: Reactome:R-HSA-2682356 "PR:O00141 located_in GO:0005829"
xref: DTO:03100471
xref: UniProtKB:O00141
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014790 ! serine/threonine-protein kinase Sgk1
relationship: has_gene_template HGNC:10810 ! SGK1 (human)

[Term]
id: PR:000014790
name: serine/threonine-protein kinase Sgk1
def: "A protein that is a translation product of the human SGK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SGK" RELATED Gene-based []
synonym: "SGK1" EXACT PRO-short-label [PRO:DNx]
synonym: "serum/glucocorticoid-regulated kinase 1" EXACT []
xref: IUPHARobj:1534
is_a: PR:000000001 ! protein