[Term]
id: PR:000014724
name: histone-lysine N-methyltransferase SETDB1
def: "A protein that is a translation product of the human SETDB1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ESET" RELATED Gene-based []
synonym: "KMT1E" RELATED Gene-based []
synonym: "SETDB1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0067" RELATED Gene-based []
synonym: "H3-K9-HMTase 4" EXACT []
synonym: "SET domain bifurcated 1" EXACT []
synonym: "lysine N-methyltransferase 1E" EXACT []
synonym: "histone H3-K9 methyltransferase 4" EXACT []
synonym: "ERG-associated protein with SET domain" EXACT []
xref: IUPHARobj:2705
is_a: PR:000000001 ! protein

[Term]
id: PR:Q15047-1
name: histone-lysine N-methyltransferase SETDB1 isoform h1 (human)
def: "A histone-lysine N-methyltransferase SETDB1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15047-1." [PRO:DNx, UniProtKB:Q15047]
comment: Category=organism-sequence.
synonym: "hSETDB1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15047-1
is_a: PR:Q15047 ! histone-lysine N-methyltransferase SETDB1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15047-2
name: histone-lysine N-methyltransferase SETDB1 isoform h2 (human)
def: "A histone-lysine N-methyltransferase SETDB1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15047-2." [PRO:DNx, UniProtKB:Q15047]
comment: Category=organism-sequence.
synonym: "hSETDB1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15047-2
is_a: PR:Q15047 ! histone-lysine N-methyltransferase SETDB1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15047-3
name: histone-lysine N-methyltransferase SETDB1 isoform h3 (human)
def: "A histone-lysine N-methyltransferase SETDB1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15047-3." [PRO:DNx, UniProtKB:Q15047]
comment: Category=organism-sequence.
synonym: "hSETDB1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15047-3
is_a: PR:Q15047 ! histone-lysine N-methyltransferase SETDB1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q15047
name: histone-lysine N-methyltransferase SETDB1 (human)
def: "A histone-lysine N-methyltransferase SETDB1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15047]
comment: Category=organism-gene.
synonym: "ESET" RELATED Gene-based [UniProtKB:Q15047]
synonym: "KMT1E" RELATED Gene-based [UniProtKB:Q15047]
synonym: "SETDB1" RELATED Gene-based [UniProtKB:Q15047]
synonym: "hSETDB1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0067" RELATED Gene-based [UniProtKB:Q15047]
synonym: "H3-K9-HMTase 4 (human)" EXACT [UniProtKB:Q15047]
synonym: "SET domain bifurcated 1 (human)" EXACT [UniProtKB:Q15047]
synonym: "lysine N-methyltransferase 1E (human)" EXACT [UniProtKB:Q15047]
synonym: "histone H3-K9 methyltransferase 4 (human)" EXACT [UniProtKB:Q15047]
synonym: "ERG-associated protein with SET domain (human)" EXACT [UniProtKB:Q15047]
xref: Reactome:R-HSA-417136 "PR:Q15047 located_in GO:0005654"
xref: UniProtKB:Q15047
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014724 ! histone-lysine N-methyltransferase SETDB1
relationship: has_gene_template HGNC:10761 ! SETDB1 (human)