[Term]
id: PR:000049209
name: glia-derived nexin, signal peptide removed form (human)
def: "A glia-derived nexin (human) that has had the signal peptide removed. UniProtKB:P07093, 20-398." [PRO:DNx, Reactome:R-HSA-4127459, Reactome:R-HSA-4127461]
comment: Category=organism-modification.
synonym: "PRO_0000032504" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hSERPINE2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07093, 20-398" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-4127459 "PR:000049209 located_in GO:0005576"
xref: Reactome:R-HSA-4127461 "PR:000049209 located_in GO:0005886"
intersection_of: PR:P07093 ! glia-derived nexin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07093
name: glia-derived nexin (human)
def: "A glia-derived nexin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07093]
comment: Category=organism-gene.
synonym: "PI7" RELATED Gene-based [UniProtKB:P07093]
synonym: "PN1" RELATED Gene-based [UniProtKB:P07093]
synonym: "SERPINE2" RELATED Gene-based [UniProtKB:P07093]
synonym: "hSERPINE2" EXACT PRO-short-label [PRO:DNx]
synonym: "GDN (human)" EXACT [UniProtKB:P07093]
synonym: "PI-7 (human)" EXACT [UniProtKB:P07093]
synonym: "PN-1 (human)" EXACT [UniProtKB:P07093]
synonym: "serpin E2 (human)" EXACT [UniProtKB:P07093]
synonym: "protease nexin 1 (human)" EXACT [UniProtKB:P07093]
synonym: "protease nexin I (human)" EXACT [UniProtKB:P07093]
synonym: "peptidase inhibitor 7 (human)" EXACT [UniProtKB:P07093]
xref: UniProtKB:P07093
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014703 ! glia-derived nexin
relationship: has_gene_template HGNC:8951 ! SERPINE2 (human)

[Term]
id: PR:000053641
name: glia-derived nexin O-glycosylated 1 (human)
def: "A glia-derived nexin (human) that has been O-glycosylated at the residue equivalent to Thr-359 of the amino acid sequence represented by UniProtKB:P07093-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P07093-1, Thr-359, MOD:00005~GNO:G43417UB." [GlyGen:P07093-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSERPINE2/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07093-1, Thr-359, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P07093 ! glia-derived nexin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000014703
name: glia-derived nexin
def: "A serpin that is a translation product of the human SERPINE2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "GDN" EXACT []
synonym: "PI7" RELATED Gene-based []
synonym: "PN1" RELATED Gene-based []
synonym: "PI-7" EXACT []
synonym: "PN-1" EXACT []
synonym: "Spi4" RELATED Gene-based []
synonym: "SERPINE2" EXACT PRO-short-label [PRO:DNx]
synonym: "serpin E2" EXACT []
synonym: "protease nexin 1" EXACT []
synonym: "protease nexin I" EXACT []
synonym: "peptidase inhibitor 7" EXACT []
synonym: "serine protease-inhibitor 4" EXACT []
is_a: PR:000025875 ! serpin

[Term]
id: PR:P07093-1
name: glia-derived nexin isoform h1 (human)
def: "A glia-derived nexin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07093-1." [PRO:DNx, UniProtKB:P07093]
comment: Category=organism-sequence.
synonym: "hSERPINE2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07093-1
is_a: PR:P07093 ! glia-derived nexin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07093-3
name: glia-derived nexin isoform h3 (human)
def: "A glia-derived nexin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07093-3." [PRO:DNx, UniProtKB:P07093]
comment: Category=organism-sequence.
synonym: "hSERPINE2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07093-3
is_a: PR:P07093 ! glia-derived nexin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07093-2
name: glia-derived nexin isoform h2 (human)
def: "A glia-derived nexin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07093-2." [PRO:DNx, UniProtKB:P07093]
comment: Category=organism-sequence.
synonym: "hSERPINE2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07093-2
is_a: PR:P07093 ! glia-derived nexin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens