[Term]
id: PR:Q03347
name: runt-related transcription factor 1 (mouse)
def: "A runt-related transcription factor 1 that is encoded in the genome of mouse." [OMA:Q03347, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aml1" RELATED Gene-based [UniProtKB:Q03347]
synonym: "Cbfa2" RELATED Gene-based [UniProtKB:Q03347]
synonym: "Runx1" RELATED Gene-based [UniProtKB:Q03347]
synonym: "mRUNX1" EXACT PRO-short-label [PRO:DNx]
synonym: "Pebp2ab" RELATED Gene-based [UniProtKB:Q03347]
synonym: "CBF-alpha-2 (mouse)" EXACT [UniProtKB:Q03347]
synonym: "PEA2-alpha B (mouse)" EXACT [UniProtKB:Q03347]
synonym: "PEBP2-alpha B (mouse)" EXACT [UniProtKB:Q03347]
synonym: "oncogene AML-1 (mouse)" EXACT [UniProtKB:Q03347]
synonym: "acute myeloid leukemia 1 protein (mouse)" EXACT [UniProtKB:Q03347]
synonym: "core-binding factor subunit alpha-2 (mouse)" EXACT [UniProtKB:Q03347]
synonym: "SL3-3 enhancer factor 1 alpha B subunit (mouse)" EXACT [UniProtKB:Q03347]
synonym: "SL3/AKV core-binding factor alpha B subunit (mouse)" EXACT [UniProtKB:Q03347]
synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit (mouse)" EXACT [UniProtKB:Q03347]
xref: UniProtKB:Q03347
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014362 ! runt-related transcription factor 1
relationship: has_gene_template MGI:99852 ! Runx1 (mouse)

[Term]
id: PR:000035624
name: runt-related transcription factor 1 isoform 3
def: "A runt-related transcription factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-3 or a 1:1 ortholog thereof." [PRO:AAA, UniProtKB:Q01196-3]
comment: Category=sequence.
synonym: "RUNX1/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014362 ! runt-related transcription factor 1

[Term]
id: PR:000035626
name: runt-related transcription factor 1 isoform 2
def: "A runt-related transcription factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-2 or a 1:1 ortholog thereof." [PRO:AAA, UniProtKB:Q01196-2]
comment: Category=sequence.
synonym: "RUNX1/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014362 ! runt-related transcription factor 1

[Term]
id: PR:000028558
name: runt-related transcription factor 1 isoform 1
def: "A runt-related transcription factor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "RUNX1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014362 ! runt-related transcription factor 1

[Term]
id: PR:Q01196-10
name: runt-related transcription factor 1 isoform hAML-1I (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-10." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1I" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-10
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196-11
name: runt-related transcription factor 1 isoform hAML-1L (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-11." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1L" EXACT PRO-short-label [PRO:DNx]
synonym: "runt-related transcription factor 1 isoform AML1-delta N (human)" EXACT [UniProtKB:Q01196]
xref: UniProtKB:Q01196-11
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196
name: runt-related transcription factor 1 (human)
def: "A runt-related transcription factor 1 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-gene.
synonym: "AML1" RELATED Gene-based [UniProtKB:Q01196]
synonym: "CBFA2" RELATED Gene-based [UniProtKB:Q01196]
synonym: "RUNX1" RELATED Gene-based [UniProtKB:Q01196]
synonym: "hRUNX1" EXACT PRO-short-label [PRO:DNx]
synonym: "CBF-alpha-2 (human)" EXACT [UniProtKB:Q01196]
synonym: "PEA2-alpha B (human)" EXACT [UniProtKB:Q01196]
synonym: "PEBP2-alpha B (human)" EXACT [UniProtKB:Q01196]
synonym: "oncogene AML-1 (human)" EXACT [UniProtKB:Q01196]
synonym: "acute myeloid leukemia 1 protein (human)" EXACT [UniProtKB:Q01196]
synonym: "core-binding factor subunit alpha-2 (human)" EXACT [UniProtKB:Q01196]
synonym: "SL3-3 enhancer factor 1 alpha B subunit (human)" EXACT [UniProtKB:Q01196]
synonym: "SL3/AKV core-binding factor alpha B subunit (human)" EXACT [UniProtKB:Q01196]
synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit (human)" EXACT [UniProtKB:Q01196]
xref: Reactome:R-HSA-5667138 "PR:Q01196 located_in GO:0005886"
xref: Reactome:R-HSA-8865295 "PR:Q01196 located_in GO:0005654"
xref: UniProtKB:Q01196
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014362 ! runt-related transcription factor 1
relationship: has_gene_template HGNC:10471 ! RUNX1 (human)

[Term]
id: PR:Q01196-8
name: runt-related transcription factor 1 isoform hAML-1G (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-8." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1G" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-8
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196-9
name: runt-related transcription factor 1 isoform hAML-1H (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-9." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1H" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-9
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196-1
name: runt-related transcription factor 1 isoform 1 (human)
def: "A runt-related transcription factor 1 isoform 1 that is encoded in the genome of human." [PRO:AAA, UniProtKB:Q01196-1]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028558 ! runt-related transcription factor 1 isoform 1

[Term]
id: PR:Q01196-2
name: runt-related transcription factor 1 isoform 2 (human)
def: "A runt-related transcription factor 1 isoform 2 that is encoded in the genome of human." [PRO:AAA, UniProtKB:Q01196-2]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035626 ! runt-related transcription factor 1 isoform 2

[Term]
id: PR:Q01196-3
name: runt-related transcription factor 1 isoform 3 (human)
def: "A runt-related transcription factor 1 isoform 3 that is encoded in the genome of human." [PRO:AAA, UniProtKB:Q01196-3]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035624 ! runt-related transcription factor 1 isoform 3

[Term]
id: PR:Q01196-4
name: runt-related transcription factor 1 isoform hAML-1E (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-4." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-4
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196-5
name: runt-related transcription factor 1 isoform hAML-1FA (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-5." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1FA" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-5
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196-6
name: runt-related transcription factor 1 isoform hAML-1FB (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-6." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1FB" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-6
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q01196-7
name: runt-related transcription factor 1 isoform hAML-1FC (human)
def: "A runt-related transcription factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01196-7." [PRO:DNx, UniProtKB:Q01196]
comment: Category=organism-sequence.
synonym: "hRUNX1/iso:hAML-1FC" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q01196-7
is_a: PR:Q01196 ! runt-related transcription factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000014362
name: runt-related transcription factor 1
def: "A protein that is a translation product of the human RUNX1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=CL.
synonym: "AML1" RELATED Gene-based []
synonym: "CBFA2" RELATED Gene-based []
synonym: "RUNX1" EXACT PRO-short-label [PRO:DNx]
synonym: "Pebp2ab" RELATED Gene-based []
synonym: "CBF-alpha-2" EXACT []
synonym: "PEA2-alpha B" EXACT []
synonym: "PEBP2-alpha B" EXACT []
synonym: "oncogene AML-1" EXACT []
synonym: "acute myeloid leukemia 1 protein" EXACT []
synonym: "core-binding factor subunit alpha-2" EXACT []
synonym: "SL3-3 enhancer factor 1 alpha B subunit" EXACT []
synonym: "SL3/AKV core-binding factor alpha B subunit" EXACT []
synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000028561
name: runt-related transcription factor 1 acetylated 1 (human)
def: "A runt-related transcription factor 1 acetylated 1 in human. Example: UniProtKB:Q01196-1, Lys-24/Lys-43, MOD:00064." [KAT:Q01196, PMID:14752096, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102).
synonym: "hRUNX1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q01196-1, Lys-24/Lys-43, MOD:00064" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028560 ! runt-related transcription factor 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000028560
name: runt-related transcription factor 1 acetylated 1
def: "A runt-related transcription factor 1 that has been N-acetylated at two conserved Lys residues in the N-terminal region of the protein previous to the Runt domain (Pfam:PF00853). Example: UniProtKB:Q01196-1, Lys-24/Lys-43, MOD:00064." [KAT:Q01196, PMID:14752096, PRO:PD]
comment: Category=modification.
synonym: "RUNX1/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000014362 ! runt-related transcription factor 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:Q03347-2
name: runt-related transcription factor 1 isoform 2 (mouse)
def: "A runt-related transcription factor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03347-2." [PMID:8164679, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mRUNX1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PEB2-alpha B2 (mouse)" EXACT []
xref: UniProtKB:Q03347-2
is_a: PR:Q03347 ! runt-related transcription factor 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q03347-3
name: runt-related transcription factor 1 isoform 3 (mouse)
def: "A runt-related transcription factor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03347-3." [EMBL:X97306, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mRUNX1/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03347-3
is_a: PR:Q03347 ! runt-related transcription factor 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q03347-1
name: runt-related transcription factor 1 isoform 1 (mouse)
def: "A runt-related transcription factor 1 isoform 1 that is encoded in the genome of mouse." [PMID:8437866, PRO:CNA, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mRUNX1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "AML1-B (mouse)" EXACT []
synonym: "PEB2-alpha B1 (mouse)" EXACT []
xref: UniProtKB:Q03347-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000028558 ! runt-related transcription factor 1 isoform 1

[Term]
id: PR:Q03347-4
name: runt-related transcription factor 1 isoform 4 (mouse)
def: "A runt-related transcription factor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03347-4." [EMBL:X97306, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mRUNX1/iso:4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03347-4
is_a: PR:Q03347 ! runt-related transcription factor 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q03347-5
name: runt-related transcription factor 1 isoform 5 (mouse)
def: "A runt-related transcription factor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03347-5." [PMID:10903914, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mRUNX1/iso:5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03347-5
is_a: PR:Q03347 ! runt-related transcription factor 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q63046
name: runt-related transcription factor 1 (rat)
def: "A runt-related transcription factor 1 that is encoded in the genome of rat." [OMA:Q63046, PANTHER:PTHR11950:SF8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Aml1" RELATED Gene-based [UniProtKB:Q63046]
synonym: "Cbfa2" RELATED Gene-based [UniProtKB:Q63046]
synonym: "Runx1" RELATED Gene-based [UniProtKB:Q63046]
synonym: "rRUNX1" EXACT PRO-short-label [PRO:DNx]
synonym: "CBF-alpha-2 (rat)" EXACT [UniProtKB:Q63046]
synonym: "PEA2-alpha B (rat)" EXACT [UniProtKB:Q63046]
synonym: "PEBP2-alpha B (rat)" EXACT [UniProtKB:Q63046]
synonym: "oncogene AML-1 (rat)" EXACT [UniProtKB:Q63046]
synonym: "acute myeloid leukemia 1 protein (rat)" EXACT [UniProtKB:Q63046]
synonym: "core-binding factor subunit alpha-2 (rat)" EXACT [UniProtKB:Q63046]
synonym: "polyomavirus enhancer-binding protein 2 alpha B subunit (rat)" EXACT [UniProtKB:Q63046]
xref: UniProtKB:Q63046
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000014362 ! runt-related transcription factor 1
relationship: has_gene_template RGD:2283 ! Runx1 (rat)