[Term]
id: PR:000014348
name: reticulon-4
def: "A protein that is a translation product of the human RTN4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NSP" RELATED []
synonym: "NOGO" RELATED Gene-based []
synonym: "RTN4" EXACT PRO-short-label [PRO:DNx]
synonym: "My043" RELATED Gene-based []
synonym: "RTN-x" EXACT []
synonym: "SP1507" RELATED Gene-based []
synonym: "foocen" EXACT []
synonym: "KIAA0886" RELATED Gene-based []
synonym: "reticulon-5" EXACT []
synonym: "nogo protein" EXACT []
synonym: "neurite outgrowth inhibitor" EXACT []
synonym: "neuroendocrine-specific protein" BROAD [PRO:DNx]
synonym: "neuroendocrine-specific protein C homolog" EXACT []
xref: IUPHARobj:2838
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9NQC3
name: reticulon-4 (human)
def: "A reticulon-4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NQC3]
comment: Category=organism-gene.
synonym: "NOGO" RELATED Gene-based [UniProtKB:Q9NQC3]
synonym: "RTN4" RELATED Gene-based [UniProtKB:Q9NQC3]
synonym: "My043" RELATED Gene-based [UniProtKB:Q9NQC3]
synonym: "hRTN4" EXACT PRO-short-label [PRO:DNx]
synonym: "SP1507" RELATED Gene-based [UniProtKB:Q9NQC3]
synonym: "KIAA0886" RELATED Gene-based [UniProtKB:Q9NQC3]
synonym: "NSP (human)" BROAD [UniProtKB:Q9NQC3]
synonym: "RTN-x (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "foocen (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-5 (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "Nogo protein (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "neurite outgrowth inhibitor (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "neuroendocrine-specific protein (human)" BROAD [UniProtKB:Q9NQC3]
synonym: "neuroendocrine-specific protein C homolog (human)" EXACT [UniProtKB:Q9NQC3]
xref: UniProtKB:Q9NQC3
xref: Reactome:R-HSA-194556 "PR:Q9NQC3 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014348 ! reticulon-4
relationship: has_gene_template HGNC:14085 ! RTN4 (human)

[Term]
id: PR:Q9NQC3-3
name: reticulon-4 isoform 3 (human)
def: "A reticulon-4 isoform 3 that is encoded in the genome of human." [PRO:CNA, TDR:2090]
comment: Category=organism-sequence. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hRTN4/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "reticulon-4 isoform Nogo-C (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN 4C (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Foocen-S (human)" EXACT [UniProtKB:Q9NQC3]
xref: UniProtKB:Q9NQC3-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000043493 ! reticulon-4 isoform 3

[Term]
id: PR:Q9NQC3-2
name: reticulon-4 isoform B (human)
def: "A reticulon-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NQC3-2." [PRO:DNx, UniProtKB:Q9NQC3]
comment: Category=organism-sequence.
synonym: "hRTN4/iso:B" EXACT PRO-short-label [PRO:DNx]
synonym: "reticulon-4 isoform ASY (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4B (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Nogo-B (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN-xS (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4B1 (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Nogo-B1 (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Foocen-M (human)" EXACT [UniProtKB:Q9NQC3]
xref: UniProtKB:Q9NQC3-2
is_a: PR:Q9NQC3 ! reticulon-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NQC3-1
name: reticulon-4 isoform A (human)
def: "A reticulon-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NQC3-1." [PRO:DNx, UniProtKB:Q9NQC3]
comment: Category=organism-sequence.
synonym: "hRTN4/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "reticulon-4 isoform RTN4A (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Nogo-A (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN-xL (human)" EXACT [UniProtKB:Q9NQC3]
xref: UniProtKB:Q9NQC3-1
is_a: PR:Q9NQC3 ! reticulon-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NQC3-6
name: reticulon-4 isoform D (human)
def: "A reticulon-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NQC3-6." [PRO:DNx, UniProtKB:Q9NQC3]
comment: Category=organism-sequence.
synonym: "hRTN4/iso:D" EXACT PRO-short-label [PRO:DNx]
synonym: "reticulon-4 isoform RTN4D (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4E (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4F (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4G (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Rtn-T (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4Aa (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform RTN4Ab (human)" EXACT [UniProtKB:Q9NQC3]
xref: UniProtKB:Q9NQC3-6
is_a: PR:Q9NQC3 ! reticulon-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NQC3-5
name: reticulon-4 isoform hB2 (human)
def: "A reticulon-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NQC3-5." [PRO:DNx, UniProtKB:Q9NQC3]
comment: Category=organism-sequence.
synonym: "hRTN4/iso:hB2" EXACT PRO-short-label [PRO:DNx]
synonym: "reticulon-4 isoform RTN4B2 (human)" EXACT [UniProtKB:Q9NQC3]
synonym: "reticulon-4 isoform Nogo-B2 (human)" EXACT [UniProtKB:Q9NQC3]
xref: UniProtKB:Q9NQC3-5
is_a: PR:Q9NQC3 ! reticulon-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NQC3-4
name: reticulon-4 isoform h6 (human)
def: "A reticulon-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NQC3-4." [PRO:DNx, UniProtKB:Q9NQC3]
comment: Category=organism-sequence.
synonym: "hRTN4/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NQC3-4
is_a: PR:Q9NQC3 ! reticulon-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens