[Term] id: PR:000014333 name: R-spondin-4 def: "A protein that is a translation product of the human RSPO4 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "RSPO4" EXACT PRO-short-label [PRO:DNx] synonym: "Rspo4" EXACT [] synonym: "C20orf182" RELATED Gene-based [] synonym: "Cristin-4" EXACT [] synonym: "cristin-4" EXACT [] synonym: "roof plate-specific spondin-4" EXACT [] synonym: "cysteine-rich and single thrombospondin domain-containing protein 4" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000049142 name: R-spondin-4, signal peptide removed form (human) def: "An R-spondin-4 (human) that has had the signal peptide removed. UniProtKB:Q2I0M5, 20-234." [PRO:DNx, Reactome:R-HSA-4641197] comment: Category=organism-modification. synonym: "PRO_0000234446" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hRSPO4/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q2I0M5, 20-234" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4641197 "PR:000049142 located_in GO:0005576" intersection_of: PR:Q2I0M5 ! R-spondin-4 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q2I0M5-2 name: R-spondin-4 isoform h2 (human) def: "An R-spondin-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2I0M5-2." [PRO:DNx, UniProtKB:Q2I0M5] comment: Category=organism-sequence. synonym: "hRSPO4/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q2I0M5-2 is_a: PR:Q2I0M5 ! R-spondin-4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q2I0M5 name: R-spondin-4 (human) def: "An R-spondin-4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q2I0M5] comment: Category=organism-gene. synonym: "RSPO4" RELATED Gene-based [UniProtKB:Q2I0M5] synonym: "hRSPO4" EXACT PRO-short-label [PRO:DNx] synonym: "hRspo4" EXACT [UniProtKB:Q2I0M5] synonym: "C20orf182" RELATED Gene-based [UniProtKB:Q2I0M5] synonym: "roof plate-specific spondin-4 (human)" EXACT [UniProtKB:Q2I0M5] xref: UniProtKB:Q2I0M5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014333 ! R-spondin-4 relationship: has_gene_template HGNC:16175 ! RSPO4 (human) [Term] id: PR:Q2I0M5-1 name: R-spondin-4 isoform h1 (human) def: "An R-spondin-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q2I0M5-1." [PRO:DNx, UniProtKB:Q2I0M5] comment: Category=organism-sequence. synonym: "hRSPO4/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q2I0M5-1 is_a: PR:Q2I0M5 ! R-spondin-4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens