[Term] id: PR:000014332 name: R-spondin-3 def: "A protein that is a translation product of the human RSPO3 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PWTSR" RELATED Gene-based [] synonym: "RSPO3" EXACT PRO-short-label [PRO:DNx] synonym: "THSD2" RELATED Gene-based [] synonym: "cabriolet" EXACT [] synonym: "cristin-1" EXACT [] synonym: "nucleopondin" EXACT [] synonym: "roof plate-specific spondin-3" EXACT [] synonym: "protein with TSP type-1 repeat" EXACT [] synonym: "thrombospondin type-1 domain-containing protein 2" EXACT [] synonym: "cysteine-rich and single thrombospondin domain-containing protein 1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q9BXY4-1 name: R-spondin-3 isoform h1 (human) def: "An R-spondin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXY4-1." [PRO:DNx, UniProtKB:Q9BXY4] comment: Category=organism-sequence. synonym: "hRSPO3/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9BXY4-1 is_a: PR:Q9BXY4 ! R-spondin-3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000049141 name: R-spondin-3, signal peptide removed form (human) def: "An R-spondin-3 (human) that has had the signal peptide removed. UniProtKB:Q9BXY4, 22-272." [PRO:DNx, Reactome:R-HSA-4641195] comment: Category=organism-modification. synonym: "PRO_0000234443" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hRSPO3/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9BXY4, 22-272" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4641195 "PR:000049141 located_in GO:0005576" intersection_of: PR:Q9BXY4 ! R-spondin-3 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9BXY4 name: R-spondin-3 (human) def: "An R-spondin-3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BXY4] comment: Category=organism-gene. synonym: "PWTSR" RELATED Gene-based [UniProtKB:Q9BXY4] synonym: "RSPO3" RELATED Gene-based [UniProtKB:Q9BXY4] synonym: "THSD2" RELATED Gene-based [UniProtKB:Q9BXY4] synonym: "hPWTSR" EXACT [UniProtKB:Q9BXY4] synonym: "hRSPO3" EXACT PRO-short-label [PRO:DNx] synonym: "hRspo3" EXACT [UniProtKB:Q9BXY4] synonym: "roof plate-specific spondin-3 (human)" EXACT [UniProtKB:Q9BXY4] synonym: "protein with TSP type-1 repeat (human)" EXACT [UniProtKB:Q9BXY4] synonym: "thrombospondin type-1 domain-containing protein 2 (human)" EXACT [UniProtKB:Q9BXY4] xref: UniProtKB:Q9BXY4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000014332 ! R-spondin-3 relationship: has_gene_template HGNC:20866 ! RSPO3 (human) [Term] id: PR:Q9BXY4-2 name: R-spondin-3 isoform h2 (human) def: "An R-spondin-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXY4-2." [PRO:DNx, UniProtKB:Q9BXY4] comment: Category=organism-sequence. synonym: "hRSPO3/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9BXY4-2 is_a: PR:Q9BXY4 ! R-spondin-3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens