[Term]
id: PR:000014137
name: E3 ubiquitin-protein ligase RNF43
def: "A protein that is a translation product of the human RNF43 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RNF43" EXACT PRO-short-label [PRO:DNx]
synonym: "RING finger protein 43" EXACT []
synonym: "RING-type E3 ubiquitin transferase RNF43" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q68DV7-1
name: E3 ubiquitin-protein ligase RNF43 isoform h1 (human)
def: "An E3 ubiquitin-protein ligase RNF43 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q68DV7-1." [PRO:DNx, UniProtKB:Q68DV7]
comment: Category=organism-sequence.
synonym: "hRNF43/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q68DV7-1
is_a: PR:Q68DV7 ! E3 ubiquitin-protein ligase RNF43 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q68DV7-2
name: E3 ubiquitin-protein ligase RNF43 isoform h2 (human)
def: "An E3 ubiquitin-protein ligase RNF43 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q68DV7-2." [PRO:DNx, UniProtKB:Q68DV7]
comment: Category=organism-sequence.
synonym: "hRNF43/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q68DV7-2
is_a: PR:Q68DV7 ! E3 ubiquitin-protein ligase RNF43 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q68DV7-3
name: E3 ubiquitin-protein ligase RNF43 isoform h3 (human)
def: "An E3 ubiquitin-protein ligase RNF43 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q68DV7-3." [PRO:DNx, UniProtKB:Q68DV7]
comment: Category=organism-sequence.
synonym: "hRNF43/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q68DV7-3
is_a: PR:Q68DV7 ! E3 ubiquitin-protein ligase RNF43 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q68DV7-4
name: E3 ubiquitin-protein ligase RNF43 isoform h4 (human)
def: "An E3 ubiquitin-protein ligase RNF43 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q68DV7-4." [PRO:DNx, UniProtKB:Q68DV7]
comment: Category=organism-sequence.
synonym: "hRNF43/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q68DV7-4
is_a: PR:Q68DV7 ! E3 ubiquitin-protein ligase RNF43 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049054
name: E3 ubiquitin-protein ligase RNF43, signal peptide removed form (human)
def: "An E3 ubiquitin-protein ligase RNF43 (human) that has had the signal peptide removed. UniProtKB:Q68DV7, 24-783." [PRO:DNx, Reactome:R-HSA-5323531]
comment: Category=organism-modification.
synonym: "PRO_0000278239" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hRNF43/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q68DV7, 24-783" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5323531 "PR:000049054 located_in GO:0005886"
intersection_of: PR:Q68DV7 ! E3 ubiquitin-protein ligase RNF43 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049055
name: E3 ubiquitin-protein ligase RNF43, signal peptide removed ubiquitinated form (human)
def: "An E3 ubiquitin-protein ligase RNF43 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q68DV7, 24-783, MOD:01148." [PRO:DNx, Reactome:R-HSA-5323547]
comment: Category=organism-modification.
synonym: "hRNF43/SigPep-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000278239, MOD:01148" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q68DV7, 24-783, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5323547 "PR:000049055 located_in GO:0005886"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q68DV7 ! E3 ubiquitin-protein ligase RNF43 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q68DV7
name: E3 ubiquitin-protein ligase RNF43 (human)
def: "An E3 ubiquitin-protein ligase RNF43 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q68DV7]
comment: Category=organism-gene.
synonym: "RNF43" RELATED Gene-based [UniProtKB:Q68DV7]
synonym: "hRNF43" EXACT PRO-short-label [PRO:DNx]
synonym: "RING finger protein 43 (human)" EXACT [UniProtKB:Q68DV7]
synonym: "RING-type E3 ubiquitin transferase RNF43 (human)" EXACT [UniProtKB:Q68DV7]
xref: UniProtKB:Q68DV7
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014137 ! E3 ubiquitin-protein ligase RNF43
relationship: has_gene_template HGNC:18505 ! RNF43 (human)