[Term]
id: PR:Q05823-1
name: 2-5A-dependent ribonuclease isoform h1 (human)
def: "A 2-5A-dependent ribonuclease (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05823-1." [PRO:DNx, UniProtKB:Q05823]
comment: Category=organism-sequence.
synonym: "hRNASEL/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05823-1
is_a: PR:Q05823 ! 2-5A-dependent ribonuclease (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q05823
name: 2-5A-dependent ribonuclease (human)
def: "A 2-5A-dependent ribonuclease that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q05823]
comment: Category=organism-gene.
synonym: "RNS4" RELATED Gene-based [UniProtKB:Q05823]
synonym: "RNASEL" RELATED Gene-based [UniProtKB:Q05823]
synonym: "hRNASEL" EXACT PRO-short-label [PRO:DNx]
synonym: "RNase L (human)" EXACT [UniProtKB:Q05823]
synonym: "ribonuclease 4 (human)" RELATED [UniProtKB:Q05823]
synonym: "ribonuclease L (human)" EXACT [UniProtKB:Q05823]
synonym: "2-5A-dependent RNase (human)" EXACT [UniProtKB:Q05823]
xref: Reactome:R-HSA-1015684 "PR:Q05823 located_in GO:0005829"
xref: Reactome:R-HSA-5223312 "PR:Q05823 located_in GO:0005759"
xref: DTO:03100455
xref: UniProtKB:Q05823
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014058 ! 2-5A-dependent ribonuclease
relationship: has_gene_template HGNC:10050 ! RNASEL (human)

[Term]
id: PR:000014058
name: 2-5A-dependent ribonuclease
def: "A protein that is a translation product of the human RNASEL gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RNS4" RELATED Gene-based []
synonym: "RNASEL" EXACT PRO-short-label [PRO:DNx]
synonym: "RNase L" EXACT []
synonym: "ribonuclease 4" RELATED []
synonym: "ribonuclease L" EXACT []
synonym: "2-5A-dependent RNase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q05823-2
name: 2-5A-dependent ribonuclease isoform h2 (human)
def: "A 2-5A-dependent ribonuclease (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05823-2." [PRO:DNx, UniProtKB:Q05823]
comment: Category=organism-sequence.
synonym: "hRNASEL/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05823-2
is_a: PR:Q05823 ! 2-5A-dependent ribonuclease (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens