[Term]
id: PR:000050226
name: renin isoform 1, signal peptide removed form (rat)
def: "A renin isoform 1, signal peptide removed form in rat. UniProtKB:P08424-1, 27-402." [PRO:HJD, UniProtKB:P08424]
comment: Category=organism-modification.
synonym: "prorenin (rat)" EXACT []
synonym: "rREN/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P08424-1, 27-402" EXACT PRO-proteoform-std [PRO:HJD]
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000021259 ! renin isoform 1, signal peptide removed form

[Term]
id: PR:000013883
name: renin
def: "An angiotensinogenase that is a translation product of the human REN gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "REN" EXACT PRO-short-label [PRO:DNx]
synonym: "angiotensinogenase" RELATED []
xref: IUPHARobj:2413
is_a: PR:000050025 ! angiotensinogenase

[Term]
id: PR:000050229
name: renin isoform 1, mature form (rat)
def: "A renin isoform 1, mature form in rat. UniProtKB:P08424-1, 65-402." [PRO:DAN, PRO:HJD]
comment: Category=organism-modification.
synonym: "renin (rat)" RELATED [PRO:DAN]
synonym: "rREN/iso:1/mature" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P08424-1, 65-402" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000021260 ! renin isoform 1, mature form
relationship: lacks_part SO:0000418 ! signal_peptide
relationship: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:000050223
name: renin isoform b (rat)
def: "A renin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08424-1, 37-402. UniProtKB:P08424-1, 37-402." [GenBank:AF117820, PMID:9933256, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence. Note: Arises from the use of an alternative promoter within intron 1 coupled with alternative splicing and use of a downstream start codon. This is a non-secreted isoform.
synonym: "rREN/iso:b" EXACT PRO-short-label [PRO:DAN]
synonym: "renin-b (rat)" EXACT [PMID:9933256]
synonym: "UniProtKB:P08424-1, 37-402" EXACT PRO-proteoform-std [PRO:DAN]
is_a: PR:P08424 ! renin (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P08424
name: renin (rat)
def: "A renin that is encoded in the genome of rat." [OMA:P08424, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ren" RELATED Gene-based [UniProtKB:P08424]
synonym: "Ren1" RELATED Gene-based [UniProtKB:P08424]
synonym: "rREN" EXACT PRO-short-label [PRO:DNx]
synonym: "angiotensinogenase (rat)" EXACT [UniProtKB:P08424]
xref: UniProtKB:P08424
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000013883 ! renin
relationship: has_gene_template RGD:3554 ! Ren1 (rat)