[Term]
id: PR:Q13972
name: Ras-specific guanine nucleotide-releasing factor 1 (human)
def: "A Ras-specific guanine nucleotide-releasing factor 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13972]
comment: Category=organism-gene.
synonym: "GNRP" RELATED Gene-based [UniProtKB:Q13972]
synonym: "GRF1" RELATED Gene-based [UniProtKB:Q13972]
synonym: "CDC25" RELATED Gene-based [UniProtKB:Q13972]
synonym: "RASGRF1" RELATED Gene-based [UniProtKB:Q13972]
synonym: "hRASGRF1" EXACT PRO-short-label [PRO:DNx]
synonym: "Ras-GRF1 (human)" EXACT [UniProtKB:Q13972]
synonym: "guanine nucleotide-releasing protein (human)" EXACT [UniProtKB:Q13972]
synonym: "Ras-specific nucleotide exchange factor CDC25 (human)" EXACT [UniProtKB:Q13972]
xref: Reactome:R-HSA-442723 "PR:Q13972 located_in GO:0005886"
xref: UniProtKB:Q13972
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013756 ! Ras-specific guanine nucleotide-releasing factor 1
relationship: has_gene_template HGNC:9875 ! RASGRF1 (human)

[Term]
id: PR:000057063
name: Ras-specific guanine nucleotide-releasing factor 1 N-glycosylated 1 (human)
def: "A Ras-specific guanine nucleotide-releasing factor 1 (human) that has been N-glycosylated at the residue equivalent to Asn-872 of the amino acid sequence represented by UniProtKB:Q13972-1, in which the glycan composition is represented by GlyTouCan:G40926MX. Example: UniProtKB:Q13972-1, Asn-872, MOD:00160~GNO:G40926MX." [GlyGen:Q13972-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hRASGRF1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13972-1, Asn-872, MOD:00160~GNO:G40926MX" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13972 ! Ras-specific guanine nucleotide-releasing factor 1 (human)
relationship: has_part GNO:G40926MX ! G40926MX
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000013756
name: Ras-specific guanine nucleotide-releasing factor 1
def: "A protein that is a translation product of the human RASGRF1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GNRP" RELATED Gene-based []
synonym: "GRF1" RELATED Gene-based []
synonym: "CDC25" RELATED Gene-based []
synonym: "CDC25Mm" EXACT []
synonym: "RASGRF1" EXACT PRO-short-label [PRO:DNx]
synonym: "ras-GRF1" EXACT []
synonym: "guanine nucleotide-releasing protein" EXACT []
synonym: "ras-specific nucleotide exchange factor CDC25" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13972-1
name: Ras-specific guanine nucleotide-releasing factor 1 isoform h1 (human)
def: "A Ras-specific guanine nucleotide-releasing factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13972-1." [PRO:DNx, UniProtKB:Q13972]
comment: Category=organism-sequence.
synonym: "hRASGRF1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13972-1
is_a: PR:Q13972 ! Ras-specific guanine nucleotide-releasing factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13972-3
name: Ras-specific guanine nucleotide-releasing factor 1 isoform h3 (human)
def: "A Ras-specific guanine nucleotide-releasing factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13972-3." [PRO:DNx, UniProtKB:Q13972]
comment: Category=organism-sequence.
synonym: "hRASGRF1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13972-3
is_a: PR:Q13972 ! Ras-specific guanine nucleotide-releasing factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13972-2
name: Ras-specific guanine nucleotide-releasing factor 1 isoform h2 (human)
def: "A Ras-specific guanine nucleotide-releasing factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13972-2." [PRO:DNx, UniProtKB:Q13972]
comment: Category=organism-sequence.
synonym: "hRASGRF1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13972-2
is_a: PR:Q13972 ! Ras-specific guanine nucleotide-releasing factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens