[Term]
id: PR:000043023
name: securin isoform 1
def: "A securin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CQJ7-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PTTG1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013486 ! securin

[Term]
id: PR:Q9CQJ7
name: securin (mouse)
def: "A securin that is encoded in the genome of mouse." [OMA:Q9CQJ7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pttg" RELATED Gene-based [UniProtKB:Q9CQJ7]
synonym: "Pttg1" RELATED Gene-based [UniProtKB:Q9CQJ7]
synonym: "mPTTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "pituitary tumor-transforming gene 1 protein (mouse)" EXACT [UniProtKB:Q9CQJ7]
xref: UniProtKB:Q9CQJ7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013486 ! securin
relationship: has_gene_template MGI:1353578 ! Pttg1 (mouse)

[Term]
id: PR:P97613
name: securin (rat)
def: "A securin that is encoded in the genome of rat." [PANTHER:PTHR10418:SF0, PRO:DAN]
comment: Category=organism-gene.
synonym: "Pttg" RELATED Gene-based [UniProtKB:P97613]
synonym: "Pttg1" RELATED Gene-based [UniProtKB:P97613]
synonym: "rPTTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "pituitary tumor-transforming gene 1 protein (rat)" EXACT [UniProtKB:P97613]
xref: UniProtKB:P97613
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000013486 ! securin
relationship: has_gene_template RGD:68359 ! Pttg1 (rat)

[Term]
id: PR:000021181
name: securin, initiator methionine removed form
def: "A securin that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "PTTG1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000013486 ! securin
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000048971
name: securin ubiquitinated form (human)
def: "A securin (human) that includes at least one ubiquitinated lysine. UniProtKB:O95997, MOD:01148." [PRO:DNx, Reactome:R-HSA-3095943]
comment: Category=organism-modification.
synonym: "hPTTG1/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O95997, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3095943 "PR:000048971 located_in GO:0005829"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:O95997 ! securin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000013486
name: securin
def: "A protein that is a translation product of the human PTTG1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EAP1" RELATED Gene-based []
synonym: "PTTG" RELATED Gene-based []
synonym: "PTTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "TUTR1" RELATED Gene-based []
synonym: "esp1-associated protein" EXACT []
synonym: "tumor-transforming protein 1" EXACT []
synonym: "pituitary tumor-transforming gene 1 protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9CQJ7-2
name: securin isoform m2 (mouse)
def: "A securin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9CQJ7-2." [PRO:DNx, UniProtKB:Q9CQJ7]
comment: Category=organism-sequence.
synonym: "mPTTG1/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9CQJ7-2
is_a: PR:Q9CQJ7 ! securin (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9CQJ7-1
name: securin isoform 1 (mouse)
def: "A securin isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPTTG1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9CQJ7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000043023 ! securin isoform 1

[Term]
id: PR:O95997
name: securin (human)
def: "A securin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O95997]
comment: Category=organism-gene.
synonym: "EAP1" RELATED Gene-based [UniProtKB:O95997]
synonym: "PTTG" RELATED Gene-based [UniProtKB:O95997]
synonym: "PTTG1" RELATED Gene-based [UniProtKB:O95997]
synonym: "TUTR1" RELATED Gene-based [UniProtKB:O95997]
synonym: "hPTTG" EXACT [UniProtKB:O95997]
synonym: "hPTTG1" EXACT PRO-short-label [PRO:DNx]
synonym: "Esp1-associated protein (human)" EXACT [UniProtKB:O95997]
synonym: "tumor-transforming protein 1 (human)" EXACT [UniProtKB:O95997]
synonym: "pituitary tumor-transforming gene 1 protein (human)" EXACT [UniProtKB:O95997]
xref: Reactome:R-HSA-174190 "PR:O95997 located_in GO:0005829"
xref: UniProtKB:O95997
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013486 ! securin
relationship: has_gene_template HGNC:9690 ! PTTG1 (human)

[Term]
id: PR:B8A4J0
name: uncharacterized protein, pttg1 translation product (zebrafish)
def: "A securin that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "z-PTTG1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B8A4J0
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000013486 ! securin
relationship: has_gene_template ZFIN:ZDB-GENE-081104-345 ! pttg1 (zebrafish)

[Term]
id: PR:P97613-1
name: securin isoform 1 (rat)
def: "A securin isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rPTTG1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97613-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000043023 ! securin isoform 1