[Term]
id: PR:000013485
name: 6-pyruvoyl tetrahydrobiopterin synthase
def: "A protein that is a translation product of the human PTS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS" EXACT []
synonym: "PTP synthase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q03393
name: 6-pyruvoyl tetrahydrobiopterin synthase (human)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q03393]
comment: Category=organism-gene.
synonym: "PTS" RELATED Gene-based [UniProtKB:Q03393]
synonym: "hPTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS (human)" EXACT [UniProtKB:Q03393]
synonym: "PTP synthase (human)" EXACT [UniProtKB:Q03393]
xref: Reactome:R-HSA-1475061 "PR:Q03393 located_in GO:0005829"
xref: UniProtKB:Q03393
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template HGNC:9689 ! PTS (human)

[Term]
id: PR:000045874
name: 6-pyruvoyl tetrahydrobiopterin synthase phosphorylated 1 (human)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase (human) that has been phosphorylated at Ser-19. UniProtKB:Q03393, Ser-19, MOD:00046." [PMID:10531334, iPTMnet:Q03393]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10531334). Status=unreviewed.
synonym: "hPTS/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q03393, Ser-19, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1475426 "PR:000045874 located_in GO:0005829"
is_a: PR:Q03393 ! 6-pyruvoyl tetrahydrobiopterin synthase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens