[Term]
id: PR:O02058-1
name: putative 6-pyruvoyl tetrahydrobiopterin synthase isoform a (worm)
def: "A putative 6-pyruvoyl tetrahydrobiopterin synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O02058-1." [PRO:DNx, UniProtKB:O02058]
comment: Category=organism-sequence.
synonym: "PTS/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O02058-1
is_a: PR:O02058 ! putative 6-pyruvoyl tetrahydrobiopterin synthase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:O02058-2
name: putative 6-pyruvoyl tetrahydrobiopterin synthase isoform b (worm)
def: "A putative 6-pyruvoyl tetrahydrobiopterin synthase (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O02058-2." [PRO:DNx, UniProtKB:O02058]
comment: Category=organism-sequence.
synonym: "PTS/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O02058-2
is_a: PR:O02058 ! putative 6-pyruvoyl tetrahydrobiopterin synthase (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:O02058
name: putative 6-pyruvoyl tetrahydrobiopterin synthase (worm)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of worm." [OMA:O02058, PANTHER:PTHR12589:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ptps-1" RELATED Gene-based [UniProtKB:O02058]
synonym: "B0041.6" RELATED Gene-based [UniProtKB:O02058]
synonym: "PTS (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS (worm)" EXACT [UniProtKB:O02058]
synonym: "PTP synthase (worm)" EXACT [UniProtKB:O02058]
xref: UniProtKB:O02058
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template WormBase:WBGene00015010 ! ptps-1 (worm)

[Term]
id: PR:P48611
name: 6-pyruvoyl tetrahydrobiopterin synthase (fruit fly)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of fruit fly." [OMA:P48611, PANTHER:PTHR12589:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "pr" RELATED Gene-based [UniProtKB:P48611]
synonym: "CG16784" RELATED Gene-based [UniProtKB:P48611]
synonym: "fly-PTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS (fruit fly)" EXACT [UniProtKB:P48611]
synonym: "PTP synthase (fruit fly)" EXACT [UniProtKB:P48611]
synonym: "protein purple (fruit fly)" EXACT [UniProtKB:P48611]
synonym: "sepiapterin synthase A (fruit fly)" EXACT [UniProtKB:P48611]
xref: UniProtKB:P48611
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template FlyBase:FBgn0003141 ! pr (fruit fly)

[Term]
id: PR:P27213-1
name: 6-pyruvoyl tetrahydrobiopterin synthase isoform 1 (rat)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rPTS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27213-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000043815 ! 6-pyruvoyl tetrahydrobiopterin synthase isoform 1

[Term]
id: PR:Q03393
name: 6-pyruvoyl tetrahydrobiopterin synthase (human)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q03393]
comment: Category=organism-gene.
synonym: "PTS" RELATED Gene-based [UniProtKB:Q03393]
synonym: "hPTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS (human)" EXACT [UniProtKB:Q03393]
synonym: "PTP synthase (human)" EXACT [UniProtKB:Q03393]
xref: Reactome:R-HSA-1475061 "PR:Q03393 located_in GO:0005829"
xref: UniProtKB:Q03393
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template HGNC:9689 ! PTS (human)

[Term]
id: PR:000043815
name: 6-pyruvoyl tetrahydrobiopterin synthase isoform 1
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R1Z7-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PTS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase

[Term]
id: PR:P27213
name: 6-pyruvoyl tetrahydrobiopterin synthase (rat)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of rat." [OMA:P27213, PANTHER:PTHR12589:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pts" RELATED Gene-based [UniProtKB:P27213]
synonym: "rPTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS (rat)" EXACT [UniProtKB:P27213]
synonym: "PTP synthase (rat)" EXACT [UniProtKB:P27213]
xref: UniProtKB:P27213
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template RGD:68367 ! Pts (rat)

[Term]
id: PR:000013485
name: 6-pyruvoyl tetrahydrobiopterin synthase
def: "A protein that is a translation product of the human PTS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS" EXACT []
synonym: "PTP synthase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9R1Z7
name: 6-pyruvoyl tetrahydrobiopterin synthase (mouse)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of mouse." [OMA:Q9R1Z7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pts" RELATED Gene-based [UniProtKB:Q9R1Z7]
synonym: "mPTS" EXACT PRO-short-label [PRO:DNx]
synonym: "PTPS (mouse)" EXACT [UniProtKB:Q9R1Z7]
synonym: "PTP synthase (mouse)" EXACT [UniProtKB:Q9R1Z7]
xref: UniProtKB:Q9R1Z7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template MGI:1338783 ! Pts (mouse)

[Term]
id: PR:Q1ZXI0
name: 6-pyruvoyl tetrahydrobiopterin synthase (Dictyostelium discoideum)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase that is encoded in the genome of Dictyostelium discoideum." [OMA:Q1ZXI0, PANTHER:PTHR12589:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ptsA" RELATED Gene-based [UniProtKB:Q1ZXI0]
synonym: "Dicty-PTS" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0279095" RELATED Gene-based [UniProtKB:Q1ZXI0]
synonym: "PTPS (Dictyostelium discoideum)" EXACT [UniProtKB:Q1ZXI0]
synonym: "PTP synthase (Dictyostelium discoideum)" EXACT [UniProtKB:Q1ZXI0]
xref: UniProtKB:Q1ZXI0
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000013485 ! 6-pyruvoyl tetrahydrobiopterin synthase
relationship: has_gene_template dictyBase:DDB_G0279095 ! ptsA (Dictyostelium discoideum)

[Term]
id: PR:Q9R1Z7-1
name: 6-pyruvoyl tetrahydrobiopterin synthase isoform 1 (mouse)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPTS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9R1Z7-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000043815 ! 6-pyruvoyl tetrahydrobiopterin synthase isoform 1

[Term]
id: PR:000045874
name: 6-pyruvoyl tetrahydrobiopterin synthase phosphorylated 1 (human)
def: "A 6-pyruvoyl tetrahydrobiopterin synthase (human) that has been phosphorylated at Ser-19. UniProtKB:Q03393, Ser-19, MOD:00046." [PMID:10531334, iPTMnet:Q03393]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10531334). Status=unreviewed.
synonym: "hPTS/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q03393, Ser-19, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1475426 "PR:000045874 located_in GO:0005829"
is_a: PR:Q03393 ! 6-pyruvoyl tetrahydrobiopterin synthase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens