[Term]
id: PR:000013448
name: tyrosine-protein phosphatase non-receptor type 1
def: "A protein that is a translation product of the human PTPN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PTP1B" RELATED Gene-based []
synonym: "PTPN1" EXACT PRO-short-label [PRO:DNx]
synonym: "PTP-1B" EXACT []
synonym: "PTP-HA2" EXACT []
synonym: "protein-tyrosine phosphatase 1B" EXACT []
synonym: "protein-tyrosine phosphatase HA2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P18031
name: tyrosine-protein phosphatase non-receptor type 1 (human)
def: "A tyrosine-protein phosphatase non-receptor type 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P18031]
comment: Category=organism-gene.
synonym: "PTP1B" RELATED Gene-based [UniProtKB:P18031]
synonym: "PTPN1" RELATED Gene-based [UniProtKB:P18031]
synonym: "hPTPN1" EXACT PRO-short-label [PRO:DNx]
synonym: "PTP-1B (human)" EXACT [UniProtKB:P18031]
synonym: "protein-tyrosine phosphatase 1B (human)" EXACT [UniProtKB:P18031]
xref: Reactome:R-HSA-210625 "PR:P18031 located_in GO:0005829"
xref: UniProtKB:P18031
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013448 ! tyrosine-protein phosphatase non-receptor type 1
relationship: has_gene_template HGNC:9642 ! PTPN1 (human)

[Term]
id: PR:000045697
name: tyrosine-protein phosphatase non-receptor type 1 phosphorylated 1 (human)
def: "A tyrosine-protein phosphatase non-receptor type 1 (human) that has been phosphorylated at Tyr-66. UniProtKB:P18031, Tyr-66, MOD:00048." [PMID:9355745, iPTMnet:P18031]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:9355745). Status=unreviewed.
synonym: "hPTPN1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P18031, Tyr-66, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P18031 ! tyrosine-protein phosphatase non-receptor type 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens