[Term]
id: PR:000013434
name: protein-tyrosine kinase 6
def: "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human PTK6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BRK" RELATED Gene-based []
synonym: "Sik" RELATED Gene-based []
synonym: "PTK6" EXACT PRO-short-label [PRO:DNx]
synonym: "breast tumor kinase" EXACT []
synonym: "tyrosine-protein kinase 6" EXACT []
synonym: "tyrosine-protein kinase BRK" EXACT []
synonym: "SRC-related intestinal kinase" EXACT []
xref: IUPHARobj:2182
is_a: PR:000002997 ! proto-oncogene SRC-like tyrosine-protein kinase

[Term]
id: PR:000048956
name: protein-tyrosine kinase 6 phosphorylated 2 (human)
def: "A protein-tyrosine kinase 6 (human) that has been post-translationally modified to include phosphotyrosine at positions 342 and 447 of the amino acid sequence represented by UniProtKB:Q13882. UniProtKB:Q13882, Tyr-342/Tyr-447, MOD:00048." [PRO:DNx, Reactome:R-HSA-8849103]
comment: Category=organism-modification.
synonym: "hPTK6/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13882, Tyr-342/Tyr-447, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8849103 "PR:000048956 located_in GO:0005829"
is_a: PR:Q13882 ! protein-tyrosine kinase 6 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048957
name: protein-tyrosine kinase 6 phosphorylated 3 (human)
def: "A protein-tyrosine kinase 6 (human) that has been post-translationally modified to include phosphotyrosine at position 351 of the amino acid sequence represented by UniProtKB:Q13882. UniProtKB:Q13882, Tyr-351, MOD:00048." [PRO:DNx, Reactome:R-HSA-8857570]
comment: Category=organism-modification.
synonym: "hPTK6/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13882, Tyr-351, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8857570 "PR:000048957 located_in GO:0005829"
is_a: PR:Q13882 ! protein-tyrosine kinase 6 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048955
name: protein-tyrosine kinase 6 phosphorylated 1 (human)
def: "A protein-tyrosine kinase 6 (human) that has been post-translationally modified to include phosphotyrosine at position 342 of the amino acid sequence represented by UniProtKB:Q13882. UniProtKB:Q13882, Tyr-342, MOD:00048." [PRO:DNx, Reactome:R-HSA-8848007, Reactome:R-HSA-8848937]
comment: Category=organism-modification.
synonym: "hPTK6/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13882, Tyr-342, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8848007 "PR:000048955 located_in GO:0005829"
xref: Reactome:R-HSA-8848937 "PR:000048955 located_in GO:0005654"
is_a: PR:Q13882 ! protein-tyrosine kinase 6 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13882-1
name: protein-tyrosine kinase 6 isoform 1 (human)
def: "A protein-tyrosine kinase 6 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPTK6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13882-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040481 ! protein-tyrosine kinase 6 isoform 1

[Term]
id: PR:Q13882
name: protein-tyrosine kinase 6 (human)
def: "A protein-tyrosine kinase 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13882]
comment: Category=organism-gene.
synonym: "BRK" RELATED Gene-based [UniProtKB:Q13882]
synonym: "PTK6" RELATED Gene-based [UniProtKB:Q13882]
synonym: "hPTK6" EXACT PRO-short-label [PRO:DNx]
synonym: "breast tumor kinase (human)" EXACT [UniProtKB:Q13882]
synonym: "tyrosine-protein kinase BRK (human)" EXACT [UniProtKB:Q13882]
xref: Reactome:R-HSA-8848000 "PR:Q13882 located_in GO:0005829"
xref: DTO:03100442
xref: UniProtKB:Q13882
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013434 ! protein-tyrosine kinase 6
relationship: has_gene_template HGNC:9617 ! PTK6 (human)

[Term]
id: PR:Q13882-2
name: protein-tyrosine kinase 6 isoform h2 (human)
def: "A protein-tyrosine kinase 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13882-2." [PRO:DNx, UniProtKB:Q13882]
comment: Category=organism-sequence.
synonym: "hPTK6/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "protein-tyrosine kinase 6 isoform ALT-PTK6 (human)" EXACT [UniProtKB:Q13882]
synonym: "protein-tyrosine kinase 6 isoform LambdaM5 (human)" EXACT [UniProtKB:Q13882]
xref: UniProtKB:Q13882-2
is_a: PR:Q13882 ! protein-tyrosine kinase 6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens