[Term]
id: PR:000056388
name: prostaglandin G/H synthase 2 N-glycosylated 5 (human)
def: "A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-53 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G46503DX. Example: UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G46503DX." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPTGS2/NGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G46503DX" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35354 ! prostaglandin G/H synthase 2 (human)
relationship: has_part GNO:G46503DX ! G46503DX
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000021167
name: prostaglandin G/H synthase 2, signal peptide removed form
def: "A prostaglandin G/H synthase 2 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "PTGS2/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000013428
name: prostaglandin G/H synthase 2
def: "A protein that is a translation product of the human PTGS2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "COX2" RELATED Gene-based []
synonym: "COX-2" EXACT []
synonym: "PES-2" EXACT []
synonym: "PTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "Tis10" RELATED Gene-based []
synonym: "PGHS-2" EXACT []
synonym: "PHS II" EXACT []
synonym: "Pghs-b" RELATED Gene-based []
synonym: "gripghs" EXACT []
synonym: "TIS10 protein" EXACT []
synonym: "PGH synthase 2" EXACT []
synonym: "cyclooxygenase-2" EXACT []
synonym: "prostaglandin H2 synthase 2" EXACT []
synonym: "prostaglandin-endoperoxide synthase 2" EXACT []
synonym: "glucocorticoid-regulated inflammatory cyclooxygenase" EXACT []
synonym: "macrophage activation-associated marker protein P71/73" EXACT []
xref: IUPHARobj:1376
is_a: PR:000000001 ! protein

[Term]
id: PR:P35354
name: prostaglandin G/H synthase 2 (human)
def: "A prostaglandin G/H synthase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35354]
comment: Category=organism-gene.
synonym: "COX2" RELATED Gene-based [UniProtKB:P35354]
synonym: "PTGS2" RELATED Gene-based [UniProtKB:P35354]
synonym: "hPTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "COX-2 (human)" EXACT [UniProtKB:P35354]
synonym: "PGHS-2 (human)" EXACT [UniProtKB:P35354]
synonym: "PHS II (human)" EXACT [UniProtKB:P35354]
synonym: "PGH synthase 2 (human)" EXACT [UniProtKB:P35354]
synonym: "cyclooxygenase-2 (human)" EXACT [UniProtKB:P35354]
synonym: "prostaglandin H2 synthase 2 (human)" EXACT [UniProtKB:P35354]
synonym: "prostaglandin-endoperoxide synthase 2 (human)" EXACT [UniProtKB:P35354]
xref: UniProtKB:P35354
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
relationship: has_gene_template HGNC:9605 ! PTGS2 (human)

[Term]
id: PR:P35354-1
name: prostaglandin G/H synthase 2 isoform 1 (human)
def: "A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPTGS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35354-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039332 ! prostaglandin G/H synthase 2 isoform 1

[Term]
id: PR:000058516
name: prostaglandin G/H synthase 2 N-glycosylated 1 (mouse)
def: "A prostaglandin G/H synthase 2 (mouse) that has been N-glycosylated at the residue equivalent to Asn-130 of the amino acid sequence represented by UniProtKB:Q05769-1, in which the glycan structure is represented by GlyTouCan:G62768NK. Example: UniProtKB:Q05769-1, Asn-130, MOD:00160~GNO:G62768NK." [GlyGen:Q05769-1, PMID:11258925, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "mPTGS2/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q05769-1, Asn-130, MOD:00160~GNO:G62768NK" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q05769-1, Asn-130, MOD:00160~UniCarbKB:4822" NARROW [PRO:DNx]
is_a: PR:Q05769 ! prostaglandin G/H synthase 2 (mouse)
relationship: has_part GNO:G62768NK ! G62768NK
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O62698
name: prostaglandin G/H synthase 2 (cow)
def: "A prostaglandin G/H synthase 2 that is encoded in the genome of cow." [OMA:O62698, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "COX2" RELATED Gene-based [UniProtKB:O62698]
synonym: "PTGS2" RELATED Gene-based [UniProtKB:O62698]
synonym: "cow-PTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "COX-2 (cow)" EXACT [UniProtKB:O62698]
synonym: "PGHS-2 (cow)" EXACT [UniProtKB:O62698]
synonym: "PHS II (cow)" EXACT [UniProtKB:O62698]
synonym: "PGH synthase 2 (cow)" EXACT [UniProtKB:O62698]
synonym: "cyclooxygenase-2 (cow)" EXACT [UniProtKB:O62698]
synonym: "prostaglandin H2 synthase 2 (cow)" EXACT [UniProtKB:O62698]
synonym: "prostaglandin-endoperoxide synthase 2 (cow)" EXACT [UniProtKB:O62698]
xref: UniProtKB:O62698
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
relationship: has_gene_template NCBIGene:282023 ! PTGS2 (cow)

[Term]
id: PR:P79208
name: prostaglandin G/H synthase 2 (sheep)
def: "A prostaglandin G/H synthase 2 that is encoded in the genome of sheep." [OMA:P79208, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "COX2" RELATED Gene-based [UniProtKB:P79208]
synonym: "PTGS2" RELATED Gene-based [UniProtKB:P79208]
synonym: "sheep-PTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "COX-2 (sheep)" EXACT [UniProtKB:P79208]
synonym: "PGHS-2 (sheep)" EXACT [UniProtKB:P79208]
synonym: "PHS II (sheep)" EXACT [UniProtKB:P79208]
synonym: "PGH synthase 2 (sheep)" EXACT [UniProtKB:P79208]
synonym: "cyclooxygenase-2 (sheep)" EXACT [UniProtKB:P79208]
synonym: "prostaglandin H2 synthase 2 (sheep)" EXACT [UniProtKB:P79208]
synonym: "prostaglandin-endoperoxide synthase 2 (sheep)" EXACT [UniProtKB:P79208]
xref: UniProtKB:P79208
intersection_of: only_in_taxon NCBITaxon:9940 ! Ovis aries
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
relationship: has_gene_template NCBIGene:443460 ! PTGS2 (sheep)

[Term]
id: PR:000056384
name: prostaglandin G/H synthase 2 N-glycosylated 1 (human)
def: "A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-130 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P35354-1, Asn-130, MOD:00160~GNO:G25079LO." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPTGS2/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35354-1, Asn-130, MOD:00160~GNO:G25079LO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35354 ! prostaglandin G/H synthase 2 (human)
relationship: has_part GNO:G25079LO ! G25079LO
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056385
name: prostaglandin G/H synthase 2 N-glycosylated 2 (human)
def: "A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-130 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G46503DX. Example: UniProtKB:P35354-1, Asn-130, MOD:00160~GNO:G46503DX." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPTGS2/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35354-1, Asn-130, MOD:00160~GNO:G46503DX" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35354 ! prostaglandin G/H synthase 2 (human)
relationship: has_part GNO:G46503DX ! G46503DX
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056386
name: prostaglandin G/H synthase 2 N-glycosylated 3 (human)
def: "A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-53 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G01650EU." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPTGS2/NGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G01650EU" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35354 ! prostaglandin G/H synthase 2 (human)
relationship: has_part GNO:G01650EU ! G01650EU
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048946
name: prostaglandin G/H synthase 2, signal peptide removed form (human)
def: "A prostaglandin G/H synthase 2 (human) that has had the signal peptide removed. UniProtKB:P35354, 18-604." [PRO:DNx, Reactome:R-HSA-61605]
comment: Category=organism-modification.
synonym: "PRO_0000023875" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPTGS2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35354, 18-604" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-61605 "PR:000048946 located_in GO:0005789"
intersection_of: PR:P35354 ! prostaglandin G/H synthase 2 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q05769
name: prostaglandin G/H synthase 2 (mouse)
def: "A prostaglandin G/H synthase 2 that is encoded in the genome of mouse." [OMA:Q05769, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cox2" RELATED Gene-based [UniProtKB:Q05769]
synonym: "Cox-2" RELATED Gene-based [UniProtKB:Q05769]
synonym: "Ptgs2" RELATED Gene-based [UniProtKB:Q05769]
synonym: "Tis10" RELATED Gene-based [UniProtKB:Q05769]
synonym: "Pghs-b" RELATED Gene-based [UniProtKB:Q05769]
synonym: "mPTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "COX-2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "PES-2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "PGHS-2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "PHS II (mouse)" EXACT [UniProtKB:Q05769]
synonym: "gripghs (mouse)" EXACT [UniProtKB:Q05769]
synonym: "TIS10 protein (mouse)" EXACT [UniProtKB:Q05769]
synonym: "PGH synthase 2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "cyclooxygenase-2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "prostaglandin H2 synthase 2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "prostaglandin-endoperoxide synthase 2 (mouse)" EXACT [UniProtKB:Q05769]
synonym: "glucocorticoid-regulated inflammatory cyclooxygenase (mouse)" EXACT [UniProtKB:Q05769]
synonym: "macrophage activation-associated marker protein P71/73 (mouse)" EXACT [UniProtKB:Q05769]
xref: UniProtKB:Q05769
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
relationship: has_gene_template MGI:97798 ! Ptgs2 (mouse)

[Term]
id: PR:P27607
name: prostaglandin G/H synthase 2 (chicken)
def: "A prostaglandin G/H synthase 2 that is encoded in the genome of chicken." [OMA:P27607, PANTHER:PTHR11903:SF5, PRO:DNx]
comment: Category=organism-gene.
synonym: "PTGS2" RELATED Gene-based [UniProtKB:P27607]
synonym: "CEF-147" RELATED Gene-based [UniProtKB:P27607]
synonym: "chick-PTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "COX-2 (chicken)" EXACT [UniProtKB:P27607]
synonym: "PGHS-2 (chicken)" EXACT [UniProtKB:P27607]
synonym: "PHS II (chicken)" EXACT [UniProtKB:P27607]
synonym: "PGH synthase 2 (chicken)" EXACT [UniProtKB:P27607]
synonym: "cyclooxygenase-2 (chicken)" EXACT [UniProtKB:P27607]
synonym: "mitogen-inducible PGHS (chicken)" EXACT [UniProtKB:P27607]
synonym: "prostaglandin H2 synthase 2 (chicken)" EXACT [UniProtKB:P27607]
synonym: "prostaglandin-endoperoxide synthase 2 (chicken)" EXACT [UniProtKB:P27607]
xref: UniProtKB:P27607
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
relationship: has_gene_template NCBIGene:396451 ! PTGS2 (chicken)

[Term]
id: PR:P35355-1
name: prostaglandin G/H synthase 2 isoform 1 (rat)
def: "A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rPTGS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35355-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039332 ! prostaglandin G/H synthase 2 isoform 1

[Term]
id: PR:P35355
name: prostaglandin G/H synthase 2 (rat)
def: "A prostaglandin G/H synthase 2 that is encoded in the genome of rat." [OMA:P35355, PANTHER:PTHR11903:SF5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cox2" RELATED Gene-based [UniProtKB:P35355]
synonym: "Cox-2" RELATED Gene-based [UniProtKB:P35355]
synonym: "Ptgs2" RELATED Gene-based [UniProtKB:P35355]
synonym: "rPTGS2" EXACT PRO-short-label [PRO:DNx]
synonym: "COX-2 (rat)" EXACT [UniProtKB:P35355]
synonym: "PGHS-2 (rat)" EXACT [UniProtKB:P35355]
synonym: "PHS II (rat)" EXACT [UniProtKB:P35355]
synonym: "PGH synthase 2 (rat)" EXACT [UniProtKB:P35355]
synonym: "cyclooxygenase-2 (rat)" EXACT [UniProtKB:P35355]
synonym: "prostaglandin H2 synthase 2 (rat)" EXACT [UniProtKB:P35355]
synonym: "prostaglandin-endoperoxide synthase 2 (rat)" EXACT [UniProtKB:P35355]
xref: UniProtKB:P35355
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000013428 ! prostaglandin G/H synthase 2
relationship: has_gene_template RGD:620349 ! Ptgs2 (rat)

[Term]
id: PR:000056387
name: prostaglandin G/H synthase 2 N-glycosylated 4 (human)
def: "A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-53 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G25079LO." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPTGS2/NGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G25079LO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35354 ! prostaglandin G/H synthase 2 (human)
relationship: has_part GNO:G25079LO ! G25079LO
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000039332
name: prostaglandin G/H synthase 2 isoform 1
def: "A prostaglandin G/H synthase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35354-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PTGS2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013428 ! prostaglandin G/H synthase 2

[Term]
id: PR:Q05769-1
name: prostaglandin G/H synthase 2 isoform 1 (mouse)
def: "A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPTGS2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05769-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039332 ! prostaglandin G/H synthase 2 isoform 1