[Term] id: PR:000048945 name: prostaglandin G/H synthase 1, signal peptide removed form (human) def: "A prostaglandin G/H synthase 1 (human) that has had the signal peptide removed. UniProtKB:P23219, 24-599." [PRO:DNx, Reactome:R-HSA-428931] comment: Category=organism-modification. synonym: "PRO_0000023868" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hPTGS1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P23219, 24-599" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-428931 "PR:000048945 located_in GO:0005789" intersection_of: PR:P23219 ! prostaglandin G/H synthase 1 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000013427 name: prostaglandin G/H synthase 1 def: "A protein that is a translation product of the human PTGS1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "COX1" RELATED Gene-based [] synonym: "COX-1" EXACT [] synonym: "PHS 1" EXACT [] synonym: "PTGS1" EXACT PRO-short-label [PRO:DNx] synonym: "PGHS-1" EXACT [] synonym: "PGH synthase 1" EXACT [] synonym: "cyclooxygenase-1" EXACT [] synonym: "prostaglandin H2 synthase 1" EXACT [] synonym: "prostaglandin-endoperoxide synthase 1" EXACT [] xref: IUPHARobj:1375 is_a: PR:000000001 ! protein [Term] id: PR:P23219 name: prostaglandin G/H synthase 1 (human) def: "A prostaglandin G/H synthase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-gene. synonym: "COX1" RELATED Gene-based [UniProtKB:P23219] synonym: "PTGS1" RELATED Gene-based [UniProtKB:P23219] synonym: "hPTGS1" EXACT PRO-short-label [PRO:DNx] synonym: "COX-1 (human)" EXACT [UniProtKB:P23219] synonym: "PHS 1 (human)" EXACT [UniProtKB:P23219] synonym: "PGHS-1 (human)" EXACT [UniProtKB:P23219] synonym: "PGH synthase 1 (human)" EXACT [UniProtKB:P23219] synonym: "cyclooxygenase-1 (human)" EXACT [UniProtKB:P23219] synonym: "prostaglandin H2 synthase 1 (human)" EXACT [UniProtKB:P23219] synonym: "prostaglandin-endoperoxide synthase 1 (human)" EXACT [UniProtKB:P23219] xref: UniProtKB:P23219 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013427 ! prostaglandin G/H synthase 1 relationship: has_gene_template HGNC:9604 ! PTGS1 (human) [Term] id: PR:P23219-3 name: prostaglandin G/H synthase 1 isoform h3 (human) def: "A prostaglandin G/H synthase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23219-3." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-sequence. synonym: "hPTGS1/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P23219-3 is_a: PR:P23219 ! prostaglandin G/H synthase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P23219-2 name: prostaglandin G/H synthase 1 isoform h2 (human) def: "A prostaglandin G/H synthase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23219-2." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-sequence. synonym: "hPTGS1/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "prostaglandin G/H synthase 1 isoform Short (human)" EXACT [UniProtKB:P23219] xref: UniProtKB:P23219-2 is_a: PR:P23219 ! prostaglandin G/H synthase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P23219-1 name: prostaglandin G/H synthase 1 isoform h1 (human) def: "A prostaglandin G/H synthase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23219-1." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-sequence. synonym: "hPTGS1/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "prostaglandin G/H synthase 1 isoform Long (human)" EXACT [UniProtKB:P23219] xref: UniProtKB:P23219-1 is_a: PR:P23219 ! prostaglandin G/H synthase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P23219-6 name: prostaglandin G/H synthase 1 isoform h6 (human) def: "A prostaglandin G/H synthase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23219-6." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-sequence. synonym: "hPTGS1/iso:h6" EXACT PRO-short-label [PRO:DNx] synonym: "prostaglandin G/H synthase 1 isoform 1b2 (human)" EXACT [UniProtKB:P23219] xref: UniProtKB:P23219-6 is_a: PR:P23219 ! prostaglandin G/H synthase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P23219-5 name: prostaglandin G/H synthase 1 isoform h5 (human) def: "A prostaglandin G/H synthase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23219-5." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-sequence. synonym: "hPTGS1/iso:h5" EXACT PRO-short-label [PRO:DNx] synonym: "prostaglandin G/H synthase 1 isoform 1b3 (human)" EXACT [UniProtKB:P23219] xref: UniProtKB:P23219-5 is_a: PR:P23219 ! prostaglandin G/H synthase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P23219-4 name: prostaglandin G/H synthase 1 isoform h4 (human) def: "A prostaglandin G/H synthase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23219-4." [PRO:DNx, UniProtKB:P23219] comment: Category=organism-sequence. synonym: "hPTGS1/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P23219-4 is_a: PR:P23219 ! prostaglandin G/H synthase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens