[Term]
id: PR:Q6P2Q9-1
name: pre-mRNA-processing-splicing factor 8 isoform 1 (human)
def: "A pre-mRNA-processing-splicing factor 8 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPRPF8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6P2Q9-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000041192 ! pre-mRNA-processing-splicing factor 8 isoform 1

[Term]
id: PR:000041192
name: pre-mRNA-processing-splicing factor 8 isoform 1
def: "A pre-mRNA-processing-splicing factor 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P2Q9-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PRPF8/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013288 ! pre-mRNA-processing-splicing factor 8

[Term]
id: PR:Q99PV0
name: pre-mRNA-processing-splicing factor 8 (mouse)
def: "A pre-mRNA-processing-splicing factor 8 that is encoded in the genome of mouse." [OMA:Q99PV0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Prp8" RELATED Gene-based [UniProtKB:Q99PV0]
synonym: "Prpf8" RELATED Gene-based [UniProtKB:Q99PV0]
synonym: "mPRPF8" EXACT PRO-short-label [PRO:DNx]
synonym: "splicing factor Prp8 (mouse)" EXACT [UniProtKB:Q99PV0]
xref: UniProtKB:Q99PV0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
relationship: has_gene_template MGI:2179381 ! Prpf8 (mouse)

[Term]
id: PR:000013288
name: pre-mRNA-processing-splicing factor 8
def: "A protein that is a translation product of the human PRPF8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Prp8" RELATED Gene-based []
synonym: "p220" BROAD [PRO:DNx]
synonym: "PRPC8" RELATED Gene-based []
synonym: "PRPF8" EXACT PRO-short-label [PRO:DNx]
synonym: "PRP8 homolog" EXACT []
synonym: "splicing factor Prp8" EXACT []
synonym: "220 kDa U5 snRNP-specific protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8T295
name: pre-mRNA-processing-splicing factor 8 homolog (Dictyostelium discoideum)
def: "A pre-mRNA-processing-splicing factor 8 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q8T295, PANTHER:PTHR11140:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "prp8" RELATED Gene-based [UniProtKB:Q8T295]
synonym: "prpf8" RELATED Gene-based [UniProtKB:Q8T295]
synonym: "Dicty-PRPF8" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0274229" RELATED Gene-based [UniProtKB:Q8T295]
synonym: "splicing factor Prp8 (Dictyostelium discoideum)" EXACT [UniProtKB:Q8T295]
xref: UniProtKB:Q8T295
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
relationship: has_gene_template dictyBase:DDB_G0274229 ! prpf8 (Dictyostelium discoideum)

[Term]
id: PR:O14187
name: pre-mRNA-splicing factor spp42 (Schizosaccharomyces pombe 972h-)
def: "A pre-mRNA-processing-splicing factor 8 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O14187, PANTHER:PTHR11140:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "cwf6" RELATED Gene-based [UniProtKB:O14187]
synonym: "spp42" RELATED Gene-based [UniProtKB:O14187]
synonym: "SPAC4F8.12c" RELATED Gene-based [UniProtKB:O14187]
synonym: "Spom972h-PRPF8" EXACT PRO-short-label [PRO:DNx]
synonym: "complexed with cdc5 protein 6 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14187]
xref: UniProtKB:O14187
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
relationship: has_gene_template PomBase:SPAC4F8.12c ! spp42 (Schizosaccharomyces pombe)

[Term]
id: PR:P33334
name: pre-mRNA-splicing factor 8 (yeast)
def: "A pre-mRNA-processing-splicing factor 8 that is encoded in the genome of yeast." [OMA:P33334, PANTHER:PTHR11140:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "DBF3" RELATED Gene-based [UniProtKB:P33334]
synonym: "PRP8" RELATED Gene-based [UniProtKB:P33334]
synonym: "RNA8" RELATED Gene-based [UniProtKB:P33334]
synonym: "USA2" RELATED Gene-based [UniProtKB:P33334]
synonym: "DNA39" RELATED Gene-based [UniProtKB:P33334]
synonym: "SLT21" RELATED Gene-based [UniProtKB:P33334]
synonym: "yPRPF8" EXACT PRO-short-label [PRO:DNx]
synonym: "YHR165C" RELATED Gene-based [UniProtKB:P33334]
xref: UniProtKB:P33334
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
relationship: has_gene_template SGD:S000001208 ! PRP8 (yeast)

[Term]
id: PR:Q6P2Q9
name: pre-mRNA-processing-splicing factor 8 (human)
def: "A pre-mRNA-processing-splicing factor 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6P2Q9]
comment: Category=organism-gene.
synonym: "PRPC8" RELATED Gene-based [UniProtKB:Q6P2Q9]
synonym: "PRPF8" RELATED Gene-based [UniProtKB:Q6P2Q9]
synonym: "hPRPF8" EXACT PRO-short-label [PRO:DNx]
synonym: "p220 (human)" BROAD [UniProtKB:Q6P2Q9]
synonym: "PRP8 homolog (human)" EXACT [UniProtKB:Q6P2Q9]
synonym: "splicing factor Prp8 (human)" EXACT [UniProtKB:Q6P2Q9]
synonym: "220 kDa U5 snRNP-specific protein (human)" EXACT [UniProtKB:Q6P2Q9]
xref: UniProtKB:Q6P2Q9
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
relationship: has_gene_template HGNC:17340 ! PRPF8 (human)

[Term]
id: PR:000048935
name: pre-mRNA-processing-splicing factor 8, initiator methionine removed form (human)
def: "A pre-mRNA-processing-splicing factor 8 (human) that has had the initiator methionine removed. UniProtKB:Q6P2Q9, 2-2335." [PRO:DNx, Reactome:R-HSA-83810]
comment: Category=organism-modification.
synonym: "PRO_0000097040" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPRPF8/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q6P2Q9, 2-2335" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-83810 "PR:000048935 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q6P2Q9 ! pre-mRNA-processing-splicing factor 8 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P34369
name: pre-mRNA-splicing factor 8 homolog (worm)
def: "A pre-mRNA-processing-splicing factor 8 that is encoded in the genome of worm." [OMA:P34369, PANTHER:PTHR11140:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "prp-8" RELATED Gene-based [UniProtKB:P34369]
synonym: "C50C3.6" RELATED Gene-based [UniProtKB:P34369]
synonym: "PRPF8 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P34369
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
relationship: has_gene_template WormBase:WBGene00004187 ! prp-8 (worm)

[Term]
id: PR:Q99PV0-1
name: pre-mRNA-processing-splicing factor 8 isoform 1 (mouse)
def: "A pre-mRNA-processing-splicing factor 8 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPRPF8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99PV0-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000041192 ! pre-mRNA-processing-splicing factor 8 isoform 1

[Term]
id: PR:000021119
name: pre-mRNA-processing-splicing factor 8, initiator methionine removed form
def: "A pre-mRNA-processing-splicing factor 8 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "PRPF8/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000013288 ! pre-mRNA-processing-splicing factor 8
intersection_of: lacks_part PR:000021937 ! initiator methionine