[Term]
id: PR:Q70Z35
name: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q70Z35]
comment: Category=organism-gene.
synonym: "PREX2" RELATED Gene-based [UniProtKB:Q70Z35]
synonym: "DEPDC2" RELATED Gene-based [UniProtKB:Q70Z35]
synonym: "hPREX2" EXACT PRO-short-label [PRO:DNx]
synonym: "P-Rex2 (human)" EXACT [UniProtKB:Q70Z35]
synonym: "DEP domain-containing protein 2 (human)" EXACT [UniProtKB:Q70Z35]
synonym: "PtdIns(3,4,5)-dependent Rac exchanger 2 (human)" EXACT [UniProtKB:Q70Z35]
xref: UniProtKB:Q70Z35
xref: Reactome:R-HSA-8850949 "PR:Q70Z35 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013203 ! phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
relationship: has_gene_template HGNC:22950 ! PREX2 (human)

[Term]
id: PR:000057517
name: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein N-glycosylated 1 (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human) that has been N-glycosylated at the residue equivalent to Asn-64 of the amino acid sequence represented by UniProtKB:Q70Z35-1, in which the glycan composition is represented by GlyTouCan:G90734RJ. Example: UniProtKB:Q70Z35-1, Asn-64, MOD:00160~GNO:G90734RJ." [GlyGen:Q70Z35-1, PMID:26791533, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPREX2/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q70Z35-1, Asn-64, MOD:00160~GNO:G90734RJ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q70Z35 ! phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human)
relationship: has_part GNO:G90734RJ ! G90734RJ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q70Z35-3
name: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform h3 (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q70Z35-3." [PRO:DNx, UniProtKB:Q70Z35]
comment: Category=organism-sequence.
synonym: "hPREX2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q70Z35-3
is_a: PR:Q70Z35 ! phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q70Z35-1
name: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform h1 (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q70Z35-1." [PRO:DNx, UniProtKB:Q70Z35]
comment: Category=organism-sequence.
synonym: "hPREX2/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform P-Rex2 (human)" EXACT [UniProtKB:Q70Z35]
xref: UniProtKB:Q70Z35-1
is_a: PR:Q70Z35 ! phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q70Z35-4
name: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform h4 (human)
def: "A phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q70Z35-4." [PRO:DNx, UniProtKB:Q70Z35]
comment: Category=organism-sequence.
synonym: "hPREX2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q70Z35-4
is_a: PR:Q70Z35 ! phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000013203
name: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
def: "A protein that is a translation product of the human PREX2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PREX2" EXACT PRO-short-label [PRO:DNx]
synonym: "DEPDC2" RELATED Gene-based []
synonym: "P-Rex2" EXACT []
synonym: "DEP domain-containing protein 2" EXACT []
synonym: "PtdIns(3,4,5)-dependent Rac exchanger 2" EXACT []
is_a: PR:000000001 ! protein