[Term]
id: PR:000048897
name: peroxiredoxin-1, initiator methionine removed form (human)
def: "A peroxiredoxin-1 (human) that has had the initiator methionine removed. UniProtKB:Q06830, 2-199." [PRO:DNx, Reactome:R-HSA-3341270]
comment: Category=organism-modification.
synonym: "PRO_0000135076" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPRDX1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06830, 2-199" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3341270 "PR:000048897 located_in GO:0005829"
xref: TDR:6694
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q06830 ! peroxiredoxin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9V3P0
name: peroxiredoxin 1 (fruit fly)
def: "A peroxiredoxin-1 that is encoded in the genome of fruit fly." [PRO:DNx]
comment: Category=organism-gene.
synonym: "TPX-1" RELATED Gene-based [UniProtKB:Q9V3P0]
synonym: "CG1633" RELATED Gene-based [UniProtKB:Q9V3P0]
synonym: "DmTPx-1" EXACT [UniProtKB:Q9V3P0]
synonym: "Jafrac1" RELATED Gene-based [UniProtKB:Q9V3P0]
synonym: "fly-PRDX1" EXACT PRO-short-label [PRO:DNx]
synonym: "DPx-4783 (fruit fly)" EXACT [UniProtKB:Q9V3P0]
synonym: "thioredoxin peroxidase (fruit fly)" EXACT [UniProtKB:Q9V3P0]
synonym: "cytosolic thioredoxin peroxidase (fruit fly)" EXACT [UniProtKB:Q9V3P0]
synonym: "thioredoxin-dependent peroxiredoxin 1 (fruit fly)" EXACT [UniProtKB:Q9V3P0]
xref: UniProtKB:Q9V3P0
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000013191 ! peroxiredoxin-1
relationship: has_gene_template FlyBase:FBgn0040309 ! Jafrac1 (fruit fly)

[Term]
id: PR:P0CB50-1
name: peroxiredoxin-1 isoform 1 (chicken)
def: "A peroxiredoxin-1 isoform 1 that is encoded in the genome of chicken." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "chick-PRDX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P0CB50-1
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000040313 ! peroxiredoxin-1 isoform 1

[Term]
id: PR:P35700
name: peroxiredoxin-1 (mouse)
def: "A peroxiredoxin-1 that is encoded in the genome of mouse." [OMA:P35700, PRO:DNx]
comment: Category=organism-gene.
synonym: "Paga" RELATED Gene-based [UniProtKB:P35700]
synonym: "Msp23" RELATED Gene-based [UniProtKB:P35700]
synonym: "Prdx1" RELATED Gene-based [UniProtKB:P35700]
synonym: "Tdpx2" RELATED Gene-based [UniProtKB:P35700]
synonym: "mPRDX1" EXACT PRO-short-label [PRO:DNx]
synonym: "OSF-3 (mouse)" EXACT [UniProtKB:P35700]
synonym: "thioredoxin peroxidase 2 (mouse)" EXACT [UniProtKB:P35700]
synonym: "osteoblast-specific factor 3 (mouse)" EXACT [UniProtKB:P35700]
synonym: "macrophage 23 kDa stress protein (mouse)" EXACT [UniProtKB:P35700]
synonym: "thioredoxin-dependent peroxiredoxin 1 (mouse)" EXACT [UniProtKB:P35700]
synonym: "thioredoxin-dependent peroxide reductase 2 (mouse)" EXACT [UniProtKB:P35700]
xref: UniProtKB:P35700
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013191 ! peroxiredoxin-1
relationship: has_gene_template MGI:99523 ! Prdx1 (mouse)

[Term]
id: PR:000036309
name: peroxiredoxin-1 acetylated 1 (mouse)
def: "A peroxiredoxin-1 that is N-terminal Met acetylated in mouse. UniProtKB:P35700, Met-1, MOD:00058." [TDR:9303]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "mPRDX1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35700, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:9303
is_a: PR:000013191 ! peroxiredoxin-1
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q06830
name: peroxiredoxin-1 (human)
def: "A peroxiredoxin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06830]
comment: Category=organism-gene.
synonym: "PAGA" RELATED Gene-based [UniProtKB:Q06830]
synonym: "PAGB" RELATED Gene-based [UniProtKB:Q06830]
synonym: "PRDX1" RELATED Gene-based [UniProtKB:Q06830]
synonym: "TDPX2" RELATED Gene-based [UniProtKB:Q06830]
synonym: "hPRDX1" EXACT PRO-short-label [PRO:DNx]
synonym: "PAG (human)" EXACT [UniProtKB:Q06830]
synonym: "NKEF-A (human)" EXACT [UniProtKB:Q06830]
synonym: "thioredoxin peroxidase 2 (human)" EXACT [UniProtKB:Q06830]
synonym: "proliferation-associated gene protein (human)" EXACT [UniProtKB:Q06830]
synonym: "thioredoxin-dependent peroxiredoxin 1 (human)" EXACT [UniProtKB:Q06830]
synonym: "natural killer cell-enhancing factor A (human)" EXACT [UniProtKB:Q06830]
synonym: "thioredoxin-dependent peroxide reductase 2 (human)" EXACT [UniProtKB:Q06830]
xref: UniProtKB:Q06830
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013191 ! peroxiredoxin-1
relationship: has_gene_template HGNC:9352 ! PRDX1 (human)

[Term]
id: PR:P35700-1
name: peroxiredoxin-1 isoform 1 (mouse)
def: "A peroxiredoxin-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPRDX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35700-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040313 ! peroxiredoxin-1 isoform 1

[Term]
id: PR:Q06830-1
name: peroxiredoxin-1 isoform 1 (human)
def: "A peroxiredoxin-1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPRDX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q06830-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040313 ! peroxiredoxin-1 isoform 1

[Term]
id: PR:000040313
name: peroxiredoxin-1 isoform 1
def: "A peroxiredoxin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06830-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PRDX1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013191 ! peroxiredoxin-1

[Term]
id: PR:P0CB50
name: peroxiredoxin-1 (chicken)
def: "A peroxiredoxin-1 that is encoded in the genome of chicken." [OMA:P0CB50, PRO:DNx]
comment: Category=organism-gene.
synonym: "PRDX1" RELATED Gene-based [UniProtKB:P0CB50]
synonym: "chick-PRDX1" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin-dependent peroxiredoxin 1 (chicken)" EXACT [UniProtKB:P0CB50]
xref: UniProtKB:P0CB50
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000013191 ! peroxiredoxin-1
relationship: has_gene_template NCBIGene:424598 ! PRDX1 (chicken)

[Term]
id: PR:000045885
name: peroxiredoxin-1 phosphorylated 1 (human)
def: "A peroxiredoxin-1 (human) that has been phosphorylated at Thr-90. UniProtKB:Q06830, Thr-90, MOD:00047." [PMID:11986303, iPTMnet:Q06830]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:11986303). Status=unreviewed.
synonym: "hPRDX1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q06830, Thr-90, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8868564 "PR:000045885 located_in GO:0005829"
is_a: PR:Q06830 ! peroxiredoxin-1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000013191
name: peroxiredoxin-1
def: "A protein that is a translation product of the human PRDX1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PAG" EXACT []
synonym: "PAGA" RELATED Gene-based []
synonym: "PAGB" RELATED Gene-based []
synonym: "Msp23" RELATED Gene-based []
synonym: "OSF-3" EXACT []
synonym: "PRDX1" EXACT PRO-short-label [PRO:DNx]
synonym: "TDPX2" RELATED Gene-based []
synonym: "NKEF-A" EXACT []
synonym: "thioredoxin peroxidase 2" EXACT []
synonym: "osteoblast-specific factor 3" EXACT []
synonym: "macrophage 23 kDa stress protein" EXACT []
synonym: "proliferation-associated gene protein" EXACT []
synonym: "thioredoxin-dependent peroxiredoxin 1" EXACT []
synonym: "natural killer cell-enhancing factor A" EXACT []
synonym: "thioredoxin-dependent peroxide reductase 2" EXACT []
is_a: PR:000000001 ! protein