[Term]
id: PR:000013107
name: protein phosphatase 1 regulatory subunit 12A
def: "A protein that is a translation product of the human PPP1R12A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MBS" RELATED Gene-based []
synonym: "MYPT1" RELATED Gene-based []
synonym: "PPP1R12A" EXACT PRO-short-label [PRO:DNx]
synonym: "myosin phosphatase target subunit 1" EXACT []
synonym: "myosin phosphatase-targeting subunit 1" EXACT []
synonym: "protein phosphatase myosin-binding subunit" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000048868
name: protein phosphatase 1 regulatory subunit 12A phosphorylated 3 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that has been post-translationally modified to include phosphothreonine at position 696, and phosphoserine at position 852 of the amino acid sequence represented by UniProtKB:O14974. UniProtKB:O14974, Thr-696, MOD:00047|Ser-852, MOD:00046." [PRO:DNx, Reactome:R-HSA-419079]
comment: Category=organism-modification.
synonym: "hPPP1R12A/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14974, Thr-696, MOD:00047|Ser-852, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-419079 "PR:000048868 located_in GO:0005829"
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048866
name: protein phosphatase 1 regulatory subunit 12A phosphorylated 1 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that has been post-translationally modified to include phosphoserine at position 473 of the amino acid sequence represented by UniProtKB:O14974. UniProtKB:O14974, Ser-473, MOD:00046." [PRO:DNx, Reactome:R-HSA-3002801]
comment: Category=organism-modification.
synonym: "hPPP1R12A/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14974, Ser-473, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3002801 "PR:000048866 located_in GO:0005654"
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048867
name: protein phosphatase 1 regulatory subunit 12A phosphorylated 2 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that has been post-translationally modified to include phosphothreonine at position 696 of the amino acid sequence represented by UniProtKB:O14974. UniProtKB:O14974, Thr-696, MOD:00047." [PRO:DNx, Reactome:R-HSA-5668956]
comment: Category=organism-modification.
synonym: "hPPP1R12A/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14974, Thr-696, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5668956 "PR:000048867 located_in GO:0005829"
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14974-1
name: protein phosphatase 1 regulatory subunit 12A isoform h1 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14974-1." [PRO:DNx, UniProtKB:O14974]
comment: Category=organism-sequence.
synonym: "hPPP1R12A/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14974-1
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14974-2
name: protein phosphatase 1 regulatory subunit 12A isoform h2 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14974-2." [PRO:DNx, UniProtKB:O14974]
comment: Category=organism-sequence.
synonym: "hPPP1R12A/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "protein phosphatase 1 regulatory subunit 12A isoform Myosin phosphatase target subunit 1 variant (human)" EXACT [UniProtKB:O14974]
xref: UniProtKB:O14974-2
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14974-3
name: protein phosphatase 1 regulatory subunit 12A isoform h3 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14974-3." [PRO:DNx, UniProtKB:O14974]
comment: Category=organism-sequence.
synonym: "hPPP1R12A/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "protein phosphatase 1 regulatory subunit 12A isoform Myosin phosphatase target subunit 1 variant 2 (human)" EXACT [UniProtKB:O14974]
xref: UniProtKB:O14974-3
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14974-4
name: protein phosphatase 1 regulatory subunit 12A isoform h4 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14974-4." [PRO:DNx, UniProtKB:O14974]
comment: Category=organism-sequence.
synonym: "hPPP1R12A/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14974-4
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14974
name: protein phosphatase 1 regulatory subunit 12A (human)
def: "A protein phosphatase 1 regulatory subunit 12A that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14974]
comment: Category=organism-gene.
synonym: "MBS" RELATED Gene-based [UniProtKB:O14974]
synonym: "MYPT1" RELATED Gene-based [UniProtKB:O14974]
synonym: "PPP1R12A" RELATED Gene-based [UniProtKB:O14974]
synonym: "hPPP1R12A" EXACT PRO-short-label [PRO:DNx]
synonym: "myosin phosphatase target subunit 1 (human)" EXACT [UniProtKB:O14974]
synonym: "myosin phosphatase-targeting subunit 1 (human)" EXACT [UniProtKB:O14974]
synonym: "protein phosphatase myosin-binding subunit (human)" EXACT [UniProtKB:O14974]
xref: Reactome:R-HSA-419070 "PR:O14974 located_in GO:0005829"
xref: UniProtKB:O14974
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013107 ! protein phosphatase 1 regulatory subunit 12A
relationship: has_gene_template HGNC:7618 ! PPP1R12A (human)

[Term]
id: PR:O14974-5
name: protein phosphatase 1 regulatory subunit 12A isoform h5 (human)
def: "A protein phosphatase 1 regulatory subunit 12A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14974-5." [PRO:DNx, UniProtKB:O14974]
comment: Category=organism-sequence.
synonym: "hPPP1R12A/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14974-5
is_a: PR:O14974 ! protein phosphatase 1 regulatory subunit 12A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens