[Term] id: PR:000044738 name: DNA-directed RNA polymerase II subunit rpb1 phosphorylated 5 (Schizosaccharomyces pombe) def: "A DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) that has been post-translationally modified to include phosphoserine at position 2 of one or more C-terminal heptad repeats (YSPTSPS)." [PMID:28367989, PRO:DAN, PomBase:VW] comment: Category=organism-modification. Requested by=PomBase. Note: This form is competent for Seb1 interaction. synonym: "Spom-rpb1/Phos:5" EXACT PRO-short-label [PRO:DAN] synonym: "S2P-Pol II (Schizosaccharomyces pombe)" EXACT [PRO:DAN, PMID:28367989] is_a: PR:000044736 ! DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe [Term] id: PR:000044739 name: DNA-directed RNA polymerase II subunit rpb1 phosphorylated 6 (Schizosaccharomyces pombe) def: "A DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) that has been post-translationally modified to include phosphoserine at position 7 of one or more C-terminal heptad repeats (YSPTSPS)." [PMID:28367989, PRO:DAN, PomBase:VW] comment: Category=organism-modification. Requested by=PomBase. Note: This form is not competent for Seb1 interaction. synonym: "Spom-rpb1/Phos:6" EXACT PRO-short-label [PRO:DAN] synonym: "S7P-Pol II (Schizosaccharomyces pombe)" EXACT [PRO:DAN, PMID:28367989] is_a: PR:000044736 ! DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe [Term] id: PR:000048846 name: DNA-directed RNA polymerase II subunit RPB1 phosphorylated 1 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at positions 2 and 5 of one or more C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1791/Ser-1794, MOD:00046." [PRO:DAN, Reactome:R-HSA-113420] comment: Category=organism-modification. synonym: "hPOLR2A/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P24928-1, Ser-1791/Ser-1794, MOD:00046" NARROW PRO-proteoform-std [PRO:DAN] xref: Reactome:R-HSA-113420 "PR:000048846 located_in GO:0005654" is_a: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P24928-1 name: DNA-directed RNA polymerase II subunit RPB1 isoform 1 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPOLR2A/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P24928-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000039128 ! DNA-directed RNA polymerase II subunit RPB1 isoform 1 [Term] id: PR:P24928-2 name: DNA-directed RNA polymerase II subunit RPB1 isoform h2 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24928-2." [PRO:DNx, UniProtKB:P24928] comment: Category=organism-sequence. synonym: "hPOLR2A/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P24928-2 is_a: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000044736 name: DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of Schizosaccharomyces pombe." [PRO:DAN] comment: Category=organism-gene. Requested by=PomBase. synonym: "Spom-rpb1" EXACT PRO-short-label [PRO:DNx] synonym: "SPBC28F2.12" RELATED [] synonym: "RNA polymerase II subunit 1 (Schizosaccharomyces pombe)" EXACT [] synonym: "RNA polymerase II subunit B1 (Schizosaccharomyces pombe)" EXACT [] synonym: "DNA-directed RNA polymerase III largest subunit (Schizosaccharomyces pombe)" EXACT [] intersection_of: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 intersection_of: has_gene_template PomBase:SPBC28F2.12 ! rpb1 (Schizosaccharomyces pombe) [Term] id: PR:000044737 name: DNA-directed RNA polymerase II subunit rpb1 phosphorylated 3 (Schizosaccharomyces pombe) def: "A DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) that has been post-translationally modified to include phosphoserine at position 5 of one or more C-terminal heptad repeats (YSPTSPS)." [PMID:28367989, PRO:DAN, PomBase:VW] comment: Category=organism-modification. Requested by=PomBase. Note: This form is competent for Seb1 interaction. synonym: "Spom-rpb1/Phos:3" EXACT PRO-short-label [PRO:DAN] synonym: "S5P-Pol II (Schizosaccharomyces pombe)" EXACT [PRO:DAN, PMID:28367989] is_a: PR:000044736 ! DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe [Term] id: PR:000048850 name: DNA-directed RNA polymerase II subunit RPB1 phosphoserine form (human) def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that includes at least one phosphorylated serine. UniProtKB:P24928, MOD:00046." [PRO:DNx, Reactome:R-HSA-6797701] comment: Category=organism-modification. synonym: "hPOLR2A/PhosSer+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P24928, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-6797701 "PR:000048850 located_in GO:0005654" intersection_of: has_part MOD:00046 ! O-phospho-L-serine intersection_of: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08775 name: DNA-directed RNA polymerase II subunit RPB1 (mouse) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of mouse." [OMA:P08775, PRO:DAN] comment: Category=organism-gene. synonym: "Polr2a" RELATED Gene-based [UniProtKB:P08775] synonym: "Rpo2-1" RELATED Gene-based [UniProtKB:P08775] synonym: "Rpii215" RELATED Gene-based [UniProtKB:P08775] synonym: "mPOLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit B1 (mouse)" EXACT [UniProtKB:P08775] synonym: "DNA-directed RNA polymerase II subunit A (mouse)" EXACT [UniProtKB:P08775] synonym: "DNA-directed RNA polymerase III largest subunit (mouse)" EXACT [UniProtKB:P08775] xref: UniProtKB:P08775 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template MGI:98086 ! Polr2a (mouse) [Term] id: PR:P18616 name: DNA-directed RNA polymerase II subunit RPB1 (Arabidopsis thaliana) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of Arabidopsis thaliana." [OMA:P18616, PRO:DNx] comment: Category=organism-gene. synonym: "RPB1" RELATED Gene-based [UniProtKB:P18616] synonym: "RPII" RELATED Gene-based [UniProtKB:P18616] synonym: "NRPB1" RELATED Gene-based [UniProtKB:P18616] synonym: "RPB205" RELATED Gene-based [UniProtKB:P18616] synonym: "F4B14.70" RELATED Gene-based [UniProtKB:P18616] synonym: "At-POLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "At4g35800" RELATED Gene-based [UniProtKB:P18616] synonym: "DNA polymerase II subunit B1 (Arabidopsis thaliana)" EXACT [UniProtKB:P18616] synonym: "DNA-directed RNA polymerase II subunit 1 (Arabidopsis thaliana)" EXACT [UniProtKB:P18616] synonym: "DNA-directed RNA polymerase II largest subunit (Arabidopsis thaliana)" EXACT [UniProtKB:P18616] xref: UniProtKB:P18616 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template Araport:AT4G35800 ! NRPB1 (Arabidopsis thaliana) [Term] id: PR:P08775-1 name: DNA-directed RNA polymerase II subunit RPB1 isoform 1 (mouse) def: "A DNA-directed RNA polymerase II subunit RPB1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mPOLR2A/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P08775-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039128 ! DNA-directed RNA polymerase II subunit RPB1 isoform 1 [Term] id: PR:000012987 name: DNA-directed RNA polymerase II subunit RPB1 def: "A protein that is a translation product of the human POLR2A gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "POLR2" RELATED Gene-based [] synonym: "POLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "Rpo2-1" RELATED Gene-based [] synonym: "Rpii215" RELATED Gene-based [] synonym: "RNA polymerase II subunit B1" EXACT [] synonym: "DNA-directed RNA polymerase II subunit A" EXACT [] synonym: "RNA-directed RNA polymerase II subunit RPB1" EXACT [] synonym: "DNA-directed RNA polymerase III largest subunit" RELATED [] is_a: PR:000000001 ! protein [Term] id: PR:P36594 name: DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe 972h-) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P36594, PRO:DAN] comment: Category=organism-gene. synonym: "rpb1" RELATED Gene-based [UniProtKB:P36594] synonym: "SPBC28F2.12" RELATED Gene-based [UniProtKB:P36594] synonym: "Spom972h-rpb1" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P36594] synonym: "RNA polymerase II subunit B1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P36594] synonym: "DNA-directed RNA polymerase III largest subunit (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P36594] xref: UniProtKB:P36594 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 intersection_of: has_gene_template PomBase:SPBC28F2.12 ! rpb1 (Schizosaccharomyces pombe) [Term] id: PR:000044740 name: DNA-directed RNA polymerase II subunit rpb1 CTD-unphosphorylated form (Schizosaccharomyces pombe) def: "A DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) that lacks phosphorylation of any C-terminal heptad repeat (YSPTSPS)." [PMID:28367989, PRO:DAN, PomBase:VW] comment: Category=organism-modification. Requested by=PomBase. Note: This form is not competent for Seb1 interaction. synonym: "Spom-rpb1/UnPhos:CTD" EXACT PRO-short-label [PRO:DAN] is_a: PR:000044736 ! DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe [Term] id: PR:P24928 name: DNA-directed RNA polymerase II subunit RPB1 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P24928] comment: Category=organism-gene. synonym: "POLR2" RELATED Gene-based [UniProtKB:P24928] synonym: "POLR2A" RELATED Gene-based [UniProtKB:P24928] synonym: "hPOLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit B1 (human)" EXACT [UniProtKB:P24928] synonym: "DNA-directed RNA polymerase II subunit A (human)" EXACT [UniProtKB:P24928] synonym: "RNA-directed RNA polymerase II subunit RPB1 (human)" EXACT [UniProtKB:P24928] synonym: "DNA-directed RNA polymerase III largest subunit (human)" BROAD [UniProtKB:P24928] xref: Reactome:R-HSA-63502 "PR:P24928 located_in GO:0005654" xref: UniProtKB:P24928 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template HGNC:9187 ! POLR2A (human) [Term] id: PR:P04052 name: DNA-directed RNA polymerase II subunit RPB1 (fruit fly) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of fruit fly." [OMA:P04052, PANTHER:PTHR19376:SF14, PRO:DNx] comment: Category=organism-gene. synonym: "CG1554" RELATED Gene-based [UniProtKB:P04052] synonym: "RpII215" RELATED Gene-based [UniProtKB:P04052] synonym: "fly-POLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit B1 (fruit fly)" EXACT [UniProtKB:P04052] synonym: "DNA-directed RNA polymerase III largest subunit (fruit fly)" EXACT [UniProtKB:P04052] xref: UniProtKB:P04052 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template FlyBase:FBgn0003277 ! RpII215 (fruit fly) [Term] id: PR:P04050 name: DNA-directed RNA polymerase II subunit RPB1 (yeast) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of yeast." [OMA:P04050, PANTHER:PTHR19376:SF14, PRO:DNx] comment: Category=organism-gene. synonym: "RPB1" RELATED Gene-based [UniProtKB:P04050] synonym: "SUA8" RELATED Gene-based [UniProtKB:P04050] synonym: "D2150" RELATED Gene-based [UniProtKB:P04050] synonym: "RPO21" RELATED Gene-based [UniProtKB:P04050] synonym: "RPB220" RELATED Gene-based [UniProtKB:P04050] synonym: "YDL140C" RELATED Gene-based [UniProtKB:P04050] synonym: "yPOLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit 1 (yeast)" EXACT [UniProtKB:P04050] synonym: "RNA polymerase II subunit B1 (yeast)" EXACT [UniProtKB:P04050] synonym: "RNA polymerase II subunit B220 (yeast)" EXACT [UniProtKB:P04050] synonym: "DNA-directed RNA polymerase III largest subunit (yeast)" RELATED [UniProtKB:P04050] xref: UniProtKB:P04050 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template SGD:S000002299 ! RPO21 (yeast) [Term] id: PR:000048847 name: DNA-directed RNA polymerase II subunit RPB1 phosphorylated 2 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at positions 2 and 7 of one or more C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1791/Ser-1796, MOD:00046." [PRO:DAN, Reactome:R-HSA-6814543] comment: Category=organism-modification. synonym: "hPOLR2A/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P24928-1, Ser-1791/Ser-1796, MOD:00046" NARROW PRO-proteoform-std [PRO:DAN] xref: Reactome:R-HSA-6814543 "PR:000048847 located_in GO:0005654" is_a: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048848 name: DNA-directed RNA polymerase II subunit RPB1 phosphorylated 3 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at position 5 of one or more C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1794, MOD:00046." [PRO:DAN, Reactome:R-HSA-77100] comment: Category=organism-modification. synonym: "hPOLR2A/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P24928-1, Ser-1794, MOD:00046" NARROW PRO-proteoform-std [PRO:DAN] xref: Reactome:R-HSA-77100 "PR:000048848 located_in GO:0005654" is_a: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000048849 name: DNA-directed RNA polymerase II subunit RPB1 phosphorylated 4 (human) def: "A DNA-directed RNA polymerase II subunit RPB1 (human) that has been post-translationally modified to include phosphoserine at positions 5 and 7 of one or more C-terminal heptad repeats (YSPTSPS) of the amino acid sequence represented by UniProtKB:P24928. Example: UniProtKB:P24928-1, Ser-1794/Ser-1796, MOD:00046." [PRO:DAN, Reactome:R-HSA-6810226] comment: Category=organism-modification. synonym: "hPOLR2A/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P24928-1, Ser-1794/Ser-1796, MOD:00046" NARROW PRO-proteoform-std [PRO:DAN] xref: Reactome:R-HSA-6810226 "PR:000048849 located_in GO:0005654" is_a: PR:P24928 ! DNA-directed RNA polymerase II subunit RPB1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16356 name: DNA-directed RNA polymerase II subunit RPB1 (worm) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of worm." [OMA:P16356, PANTHER:PTHR19376:SF14, PRO:DNx] comment: Category=organism-gene. synonym: "ama-1" RELATED Gene-based [UniProtKB:P16356] synonym: "rpb-1" RELATED Gene-based [UniProtKB:P16356] synonym: "F36A4.7" RELATED Gene-based [UniProtKB:P16356] synonym: "POLR2A (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit B1 (worm)" EXACT [UniProtKB:P16356] synonym: "DNA-directed RNA polymerase III largest subunit (worm)" EXACT [UniProtKB:P16356] xref: UniProtKB:P16356 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template WormBase:WBGene00000123 ! ama-1 (worm) [Term] id: PR:000050494 name: DNA-directed RNA polymerase II subunit rpb1 CTD-phosphorylated form (Schizosaccharomyces pombe) def: "A DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) that has been phosphorylated at either position 2, 5, or 7 of one or more C-terminal heptad repeats (YSPTSPS)." [PMID:28367989, PRO:DAN, PomBase:VW] comment: Category=organism-modification. Requested by=PomBase. synonym: "Spom-rpb1/Phos:CTD" EXACT PRO-short-label [PRO:DAN] is_a: PR:000044736 ! DNA-directed RNA polymerase II subunit rpb1 (Schizosaccharomyces pombe) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:4896 ! Schizosaccharomyces pombe [Term] id: PR:000039128 name: DNA-directed RNA polymerase II subunit RPB1 isoform 1 def: "A DNA-directed RNA polymerase II subunit RPB1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24928-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "POLR2A/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 [Term] id: PR:P35084 name: DNA-directed RNA polymerase II subunit rpb1 (Dictyostelium discoideum) def: "A DNA-directed RNA polymerase II subunit RPB1 that is encoded in the genome of Dictyostelium discoideum." [OMA:P35084, PANTHER:PTHR19376:SF14, PRO:DNx] comment: Category=organism-gene. synonym: "rpb1" RELATED Gene-based [UniProtKB:P35084] synonym: "rpoA" RELATED Gene-based [UniProtKB:P35084] synonym: "polr2a" RELATED Gene-based [UniProtKB:P35084] synonym: "DDB_G0279193" RELATED Gene-based [UniProtKB:P35084] synonym: "Dicty-POLR2A" EXACT PRO-short-label [PRO:DNx] synonym: "RNA polymerase II subunit B1 (Dictyostelium discoideum)" EXACT [UniProtKB:P35084] synonym: "DNA-directed RNA polymerase III subunit A (Dictyostelium discoideum)" RELATED [UniProtKB:P35084] xref: UniProtKB:P35084 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000012987 ! DNA-directed RNA polymerase II subunit RPB1 relationship: has_gene_template dictyBase:DDB_G0279193 ! rpb1 (Dictyostelium discoideum)