[Term]
id: PR:Q9Y253
name: DNA polymerase eta (human)
def: "A DNA polymerase eta that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y253]
comment: Category=organism-gene.
synonym: "XPV" RELATED Gene-based [UniProtKB:Q9Y253]
synonym: "POLH" RELATED Gene-based [UniProtKB:Q9Y253]
synonym: "RAD30" RELATED Gene-based [UniProtKB:Q9Y253]
synonym: "hPOLH" EXACT PRO-short-label [PRO:DNx]
synonym: "RAD30A" RELATED Gene-based [UniProtKB:Q9Y253]
synonym: "RAD30 homolog A (human)" EXACT [UniProtKB:Q9Y253]
synonym: "xeroderma pigmentosum variant type protein (human)" EXACT [UniProtKB:Q9Y253]
xref: UniProtKB:Q9Y253
xref: Reactome:R-HSA-110287 "PR:Q9Y253 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012975 ! DNA polymerase eta
relationship: has_gene_template HGNC:9181 ! POLH (human)

[Term]
id: PR:Q9Y253-2
name: DNA polymerase eta isoform h2 (human)
def: "A DNA polymerase eta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y253-2." [PRO:DNx, UniProtKB:Q9Y253]
comment: Category=organism-sequence.
synonym: "hPOLH/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y253-2
is_a: PR:Q9Y253 ! DNA polymerase eta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y253-1
name: DNA polymerase eta isoform 1 (human)
def: "A DNA polymerase eta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y253-1." [PRO:DNx, UniProtKB:Q9Y253]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hPOLH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y253-1
is_a: PR:Q9Y253 ! DNA polymerase eta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048845
name: DNA polymerase eta ubiquitinated 1 (human)
def: "A DNA polymerase eta (human) that has been post-translationally modified to include ubiquitinated lysine at positions 682, 686, 694 and 709 of the amino acid sequence represented by UniProtKB:Q9Y253. UniProtKB:Q9Y253, Lys-682/Lys-686/Lys-694/Lys-709, MOD:01148." [PRO:DNx, Reactome:R-HSA-5655163]
comment: Category=organism-modification.
synonym: "hPOLH/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y253, Lys-682/Lys-686/Lys-694/Lys-709, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5655163 "PR:000048845 located_in GO:0005654"
is_a: PR:Q9Y253 ! DNA polymerase eta (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012975
name: DNA polymerase eta
def: "A protein that is a translation product of the human POLH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "XPV" RELATED Gene-based []
synonym: "POLH" EXACT PRO-short-label [PRO:DNx]
synonym: "RAD30" RELATED Gene-based []
synonym: "RAD30A" RELATED Gene-based []
synonym: "RAD30 homolog A" EXACT []
synonym: "xeroderma pigmentosum variant type protein" EXACT []
synonym: "xeroderma pigmentosum variant type protein homolog" EXACT []
is_a: PR:000000001 ! protein