[Term] id: PR:000028604 name: DNA polymerase beta acetylated 1 (human) def: "A DNA polymerase beta acetylated 1 in human. UniProtKB:P06746, Lys-72, MOD:00064." [KAT:P06746, PMID:12453427, PRO:PD] comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102). synonym: "hPOLB/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P06746, Lys-72, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028603 ! DNA polymerase beta acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:P06766 name: DNA polymerase beta (rat) def: "A DNA polymerase beta that is encoded in the genome of rat." [OMA:P06766, PANTHER:PTHR11276:SF11, PRO:DNx] comment: Category=organism-gene. synonym: "Polb" RELATED Gene-based [UniProtKB:P06766] synonym: "rPOLB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06766 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012962 ! DNA polymerase beta relationship: has_gene_template RGD:3363 ! Polb (rat) [Term] id: PR:000028601 name: DNA polymerase beta isoform 1 def: "A DNA polymerase beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P06746-1 or a 1:1 ortholog thereof." [KAT:P06746, PMID:12453427, PRO:PD] comment: Category=sequence. synonym: "POLB/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012962 ! DNA polymerase beta [Term] id: PR:000045373 name: DNA polymerase beta unacetylated 1 (human) def: "A DNA polymerase beta (human) that lacks acetylation on the residue equivalent to Lys-72 of the amino acid sequence represented by UniProtKB:P06746. UniProtKB:P06746, Lys-72, PR:000026291." [PMID:12453427, PRO:CNA] comment: Category=organism-modification. synonym: "hPOLB/UnAc:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P06746, Lys-72, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx] synonym: "DNA polymerase beta unmodified form (human)" EXACT [] is_a: PR:P06746 ! DNA polymerase beta (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000028603 name: DNA polymerase beta acetylated 1 def: "A DNA polymerase beta that is acetylated on the active site Lys residue. Example: UniProtKB:P06746, Lys-72, MOD:00064." [KAT:P06746, PMID:12453427, PRO:PD] comment: Category=modification. synonym: "POLB/Ac:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012962 ! DNA polymerase beta relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000012962 name: DNA polymerase beta def: "A protein that is a translation product of the human POLB gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "POLB" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000001 ! protein [Term] id: PR:Q8K409 name: DNA polymerase beta (mouse) def: "A DNA polymerase beta that is encoded in the genome of mouse." [OMA:Q8K409, PRO:DNx] comment: Category=organism-gene. synonym: "Polb" RELATED Gene-based [UniProtKB:Q8K409] synonym: "mPOLB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8K409 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012962 ! DNA polymerase beta relationship: has_gene_template MGI:97740 ! Polb (mouse) [Term] id: PR:000048840 name: DNA polymerase beta, initiator methionine removed ubiquitinated form (human) def: "A DNA polymerase beta (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:P06746, 2-335, MOD:01148." [PRO:DNx, Reactome:R-HSA-6783152] comment: Category=organism-modification. synonym: "hPOLB/InitMet-/UbiqLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P06746, 2-335, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-6783152 "PR:000048840 located_in GO:0005654" intersection_of: has_part MOD:01148 ! ubiquitinylated lysine intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P06746 ! DNA polymerase beta (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6DRD3 name: DNA polymerase beta (zebrafish) def: "A DNA polymerase beta that is encoded in the genome of zebrafish." [OMA:Q6DRD3, PANTHER:PTHR11276:SF11, PRO:DNx] comment: Category=organism-gene. synonym: "polb" RELATED Gene-based [UniProtKB:Q6DRD3] synonym: "z-POLB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6DRD3 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000012962 ! DNA polymerase beta relationship: has_gene_template ZFIN:ZDB-GENE-040830-1 ! polb (zebrafish) [Term] id: PR:Q9FNY4 name: DNA polymerase lambda (Arabidopsis thaliana) def: "A DNA polymerase beta that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9FNY4, PRO:DNx] comment: Category=organism-gene. synonym: "POLL" RELATED Gene-based [UniProtKB:Q9FNY4] synonym: "At-POLB" EXACT PRO-short-label [PRO:DNx] synonym: "At1g10520" RELATED Gene-based [UniProtKB:Q9FNY4] synonym: "T10O24.13" RELATED Gene-based [UniProtKB:Q9FNY4] synonym: "pol Lambda (Arabidopsis thaliana)" EXACT [UniProtKB:Q9FNY4] xref: UniProtKB:Q9FNY4 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000012962 ! DNA polymerase beta relationship: has_gene_template Araport:AT1G10520 ! Pol-lambda (Arabidopsis thaliana) [Term] id: PR:P06746-1 name: DNA polymerase beta isoform 1 (human) def: "A DNA polymerase beta isoform 1 that is encoded in the genome of human." [PRO:PD] comment: Category=organism-sequence. synonym: "hPOLB/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06746-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028601 ! DNA polymerase beta isoform 1 [Term] id: PR:000048839 name: DNA polymerase beta, initiator methionine removed form (human) def: "A DNA polymerase beta (human) that has had the initiator methionine removed. UniProtKB:P06746, 2-335." [PRO:DNx, Reactome:R-HSA-53845] comment: Category=organism-modification. synonym: "hPOLB/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P06746, 2-335" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-53845 "PR:000048839 located_in GO:0005654" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P06746 ! DNA polymerase beta (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P06746 name: DNA polymerase beta (human) def: "A DNA polymerase beta that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-gene. synonym: "POLB" RELATED Gene-based [UniProtKB:P06746] synonym: "hPOLB" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P06746 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012962 ! DNA polymerase beta relationship: has_gene_template HGNC:9174 ! POLB (human)