[Term]
id: PR:000012922
name: phosphomevalonate kinase
def: "A protein that is a translation product of the human PMVK gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PMK" EXACT []
synonym: "PMKI" RELATED Gene-based []
synonym: "PMVK" EXACT PRO-short-label [PRO:DNx]
synonym: "PMKase" EXACT []
xref: IUPHARobj:641
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9D1G2-3
name: phosphomevalonate kinase isoform m3 (mouse)
def: "A phosphomevalonate kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D1G2-3." [PRO:DNx, UniProtKB:Q9D1G2]
comment: Category=organism-sequence.
synonym: "mPMVK/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9D1G2-3
is_a: PR:Q9D1G2 ! phosphomevalonate kinase (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q15126
name: phosphomevalonate kinase (human)
def: "A phosphomevalonate kinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15126]
comment: Category=organism-gene.
synonym: "PMKI" RELATED Gene-based [UniProtKB:Q15126]
synonym: "PMVK" RELATED Gene-based [UniProtKB:Q15126]
synonym: "hPMK" EXACT [UniProtKB:Q15126]
synonym: "hPMVK" EXACT PRO-short-label [PRO:DNx]
synonym: "PMKase (human)" EXACT [UniProtKB:Q15126]
xref: UniProtKB:Q15126
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012922 ! phosphomevalonate kinase
relationship: has_gene_template HGNC:9141 ! PMVK (human)

[Term]
id: PR:Q9D1G2
name: phosphomevalonate kinase (mouse)
def: "A phosphomevalonate kinase that is encoded in the genome of mouse." [OMA:Q9D1G2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pmvk" RELATED Gene-based [UniProtKB:Q9D1G2]
synonym: "mPMVK" EXACT PRO-short-label [PRO:DNx]
synonym: "PMKase (mouse)" EXACT [UniProtKB:Q9D1G2]
xref: UniProtKB:Q9D1G2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012922 ! phosphomevalonate kinase
relationship: has_gene_template MGI:1915853 ! Pmvk (mouse)

[Term]
id: PR:Q9D1G2-1
name: phosphomevalonate kinase isoform 1 (mouse)
def: "A phosphomevalonate kinase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPMVK/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9D1G2-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040598 ! phosphomevalonate kinase isoform 1

[Term]
id: PR:000040598
name: phosphomevalonate kinase isoform 1
def: "A phosphomevalonate kinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15126-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PMVK/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000012922 ! phosphomevalonate kinase

[Term]
id: PR:000048832
name: phosphomevalonate kinase, initiator methionine removed form (human)
def: "A phosphomevalonate kinase (human) that has had the initiator methionine removed. UniProtKB:Q15126, 2-192." [PRO:DNx, Reactome:R-HSA-191348]
comment: Category=organism-modification.
synonym: "hPMVK/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q15126, 2-192" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-191348 "PR:000048832 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q15126 ! phosphomevalonate kinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9D1G2-2
name: phosphomevalonate kinase isoform m2 (mouse)
def: "A phosphomevalonate kinase (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9D1G2-2." [PRO:DNx, UniProtKB:Q9D1G2]
comment: Category=organism-sequence.
synonym: "mPMVK/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9D1G2-2
is_a: PR:Q9D1G2 ! phosphomevalonate kinase (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q15126-1
name: phosphomevalonate kinase isoform 1 (human)
def: "A phosphomevalonate kinase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPMVK/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q15126-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040598 ! phosphomevalonate kinase isoform 1

[Term]
id: PR:Q9VIT2
name: probable phosphomevalonate kinase (fruit fly)
def: "A phosphomevalonate kinase that is encoded in the genome of fruit fly." [OMA:Q9VIT2, PANTHER:PTHR13101:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "CG10268" RELATED Gene-based [UniProtKB:Q9VIT2]
synonym: "fly-PMVK" EXACT PRO-short-label [PRO:DNx]
synonym: "PMKase (fruit fly)" EXACT [UniProtKB:Q9VIT2]
xref: UniProtKB:Q9VIT2
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000012922 ! phosphomevalonate kinase
relationship: has_gene_template FlyBase:FBgn0032811 ! CG10268 (fruit fly)