[Term]
id: PR:000012860
name: pleckstrin homology domain-containing family G member 2
def: "A protein that is a translation product of the human PLEKHG2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PLEKHG2" EXACT PRO-short-label [PRO:DNx]
synonym: "common site lymphoma/leukemia GEF" EXACT []
synonym: "PH domain-containing family G member 2" EXACT []
synonym: "common site lymphoma/leukemia guanine nucleotide exchange factor" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9H7P9
name: pleckstrin homology domain-containing family G member 2 (human)
def: "A pleckstrin homology domain-containing family G member 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H7P9]
comment: Category=organism-gene.
synonym: "PLEKHG2" RELATED Gene-based [UniProtKB:Q9H7P9]
synonym: "hPLEKHG2" EXACT PRO-short-label [PRO:DNx]
synonym: "PH domain-containing family G member 2 (human)" EXACT [UniProtKB:Q9H7P9]
xref: UniProtKB:Q9H7P9
xref: Reactome:R-HSA-195043 "PR:Q9H7P9 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012860 ! pleckstrin homology domain-containing family G member 2
relationship: has_gene_template HGNC:29515 ! PLEKHG2 (human)

[Term]
id: PR:Q9H7P9-1
name: pleckstrin homology domain-containing family G member 2 isoform h1 (human)
def: "A pleckstrin homology domain-containing family G member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7P9-1." [PRO:DNx, UniProtKB:Q9H7P9]
comment: Category=organism-sequence.
synonym: "hPLEKHG2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H7P9-1
is_a: PR:Q9H7P9 ! pleckstrin homology domain-containing family G member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H7P9-2
name: pleckstrin homology domain-containing family G member 2 isoform h2 (human)
def: "A pleckstrin homology domain-containing family G member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7P9-2." [PRO:DNx, UniProtKB:Q9H7P9]
comment: Category=organism-sequence.
synonym: "hPLEKHG2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H7P9-2
is_a: PR:Q9H7P9 ! pleckstrin homology domain-containing family G member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H7P9-3
name: pleckstrin homology domain-containing family G member 2 isoform h3 (human)
def: "A pleckstrin homology domain-containing family G member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7P9-3." [PRO:DNx, UniProtKB:Q9H7P9]
comment: Category=organism-sequence.
synonym: "hPLEKHG2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H7P9-3
is_a: PR:Q9H7P9 ! pleckstrin homology domain-containing family G member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046061
name: pleckstrin homology domain-containing family G member 2 phosphorylated 1 (human)
def: "A pleckstrin homology domain-containing family G member 2 (human) that has been phosphorylated at the position equivalent to Tyr-489 of the amino acid sequence represented by UniProtKB:Q9H7P9-1. Example: UniProtKB:Q9H7P9-1, Tyr-489, MOD:00048." [PMID:24378532, iPTMnet:Q9H7P9]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:24378532). Status=unreviewed.
synonym: "hPLEKHG2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9H7P9-1, Tyr-489, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9H7P9 ! pleckstrin homology domain-containing family G member 2 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens