[Term]
id: PR:000012656
name: D-3-phosphoglycerate dehydrogenase
def: "A protein that is a translation product of the human PHGDH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "A10" EXACT []
synonym: "PGDH3" RELATED Gene-based []
synonym: "PHGDH" EXACT PRO-short-label [PRO:DNx]
synonym: "3-PGDH" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O43175-1
name: D-3-phosphoglycerate dehydrogenase isoform 1 (human)
def: "A D-3-phosphoglycerate dehydrogenase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPHGDH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43175-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038110 ! D-3-phosphoglycerate dehydrogenase isoform 1

[Term]
id: PR:O43175
name: D-3-phosphoglycerate dehydrogenase (human)
def: "A D-3-phosphoglycerate dehydrogenase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43175]
comment: Category=organism-gene.
synonym: "PGDH3" RELATED Gene-based [UniProtKB:O43175]
synonym: "PHGDH" RELATED Gene-based [UniProtKB:O43175]
synonym: "hPHGDH" EXACT PRO-short-label [PRO:DNx]
synonym: "3-PGDH (human)" EXACT [UniProtKB:O43175]
synonym: "malate dehydrogenase (human)" EXACT [UniProtKB:O43175]
synonym: "2-oxoglutarate reductase (human)" EXACT [UniProtKB:O43175]
xref: UniProtKB:O43175
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012656 ! D-3-phosphoglycerate dehydrogenase
relationship: has_gene_template HGNC:8923 ! PHGDH (human)

[Term]
id: PR:000048762
name: D-3-phosphoglycerate dehydrogenase, initiator methionine removed form (human)
def: "A D-3-phosphoglycerate dehydrogenase (human) that has had the initiator methionine removed. UniProtKB:O43175, 2-533." [PRO:DNx, Reactome:R-HSA-977340]
comment: Category=organism-modification.
synonym: "PRO_0000076012" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPHGDH/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43175, 2-533" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-977340 "PR:000048762 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:O43175 ! D-3-phosphoglycerate dehydrogenase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens