[Term] id: PR:000012586 name: profilin-2 def: "A profilin that is a translation product of the human PFN2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "PFN2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin II" EXACT [] is_a: PR:000050050 ! profilin [Term] id: PR:Q9JJV2 name: profilin-2 (mouse) def: "A profilin-2 that is encoded in the genome of mouse." [OMA:Q9JJV2, PRO:DNx] comment: Category=organism-gene. synonym: "Pfn2" RELATED Gene-based [UniProtKB:Q9JJV2] synonym: "mPFN2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin II (mouse)" EXACT [UniProtKB:Q9JJV2] xref: UniProtKB:Q9JJV2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012586 ! profilin-2 relationship: has_gene_template MGI:97550 ! Pfn2 (mouse) [Term] id: PR:Q9EPC6-2 name: profilin-2 isoform IIb (rat) def: "A profilin-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EPC6-2." [PRO:DNx, UniProtKB:Q9EPC6] comment: Category=organism-sequence. synonym: "rPFN2/iso:IIb" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9EPC6-2 is_a: PR:Q9EPC6 ! profilin-2 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:Q9JJV2-3 name: profilin-2 isoform m3 (mouse) def: "A profilin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJV2-3." [PRO:DNx, UniProtKB:Q9JJV2] comment: Category=organism-sequence. synonym: "mPFN2/iso:m3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JJV2-3 is_a: PR:Q9JJV2 ! profilin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9EPC6-1 name: profilin-2 isoform IIa (rat) def: "A profilin-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EPC6-1." [PRO:DNx, UniProtKB:Q9EPC6] comment: Category=organism-sequence. synonym: "rPFN2/iso:IIa" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9EPC6-1 is_a: PR:Q9EPC6 ! profilin-2 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P35080-1 name: profilin-2 isoform 1 (human) def: "A profilin-2 isoform 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P35080] comment: Category=organism-sequence. synonym: "hPFN2/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "profilin-2 isoform IIa (human)" EXACT [] xref: UniProtKB:P35080-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000037455 ! profilin-2 isoform 1 [Term] id: PR:P35080-2 name: profilin-2 isoform 2 (human) def: "A profilin-2 isoform 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P35080] comment: Category=organism-sequence. synonym: "hPFN2/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin-2 isoform IIb (human)" EXACT [] xref: UniProtKB:P35080-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000037456 ! profilin-2 isoform 2 [Term] id: PR:000037455 name: profilin-2 isoform 1 def: "A profilin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJV2-1 or a 1:1 ortholog thereof." [PMID:11034907, PRO:HJD] comment: Category=sequence. synonym: "PFN2/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "profilin-2soform IIa" EXACT [] is_a: PR:000012586 ! profilin-2 [Term] id: PR:Q9JJV2-2 name: profilin-2 isoform 2 (mouse) def: "A profilin-2 isoform 2 that is encoded in the genome of mouse." [PMID:11034907, PRO:HJD] comment: Category=organism-sequence. synonym: "mPFN2/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin-2 isoform IIb (mouse)" EXACT [] xref: UniProtKB:Q9JJV2-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000037456 ! profilin-2 isoform 2 [Term] id: PR:000037456 name: profilin-2 isoform 2 def: "A profilin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JJV2-2 or a 1:1 ortholog thereof." [PMID:11034907, PRO:HJD] comment: Category=sequence. synonym: "PFN2/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin-2soform IIb" EXACT [] is_a: PR:000012586 ! profilin-2 [Term] id: PR:Q9JJV2-1 name: profilin-2 isoform 1 (mouse) def: "A profilin-2 isoform 1 that is encoded in the genome of mouse." [PMID:11034907, PRO:HJD] comment: Category=organism-sequence. synonym: "mPFN2/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "profilin-2 isoform IIa (mouse)" EXACT [] xref: UniProtKB:Q9JJV2-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000037455 ! profilin-2 isoform 1 [Term] id: PR:P35080 name: profilin-2 (human) def: "A profilin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35080] comment: Category=organism-gene. synonym: "PFN2" RELATED Gene-based [UniProtKB:P35080] synonym: "hPFN2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin II (human)" EXACT [UniProtKB:P35080] xref: Reactome:R-HSA-3009037 "PR:P35080 located_in GO:0005829" xref: UniProtKB:P35080 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012586 ! profilin-2 relationship: has_gene_template HGNC:8882 ! PFN2 (human) [Term] id: PR:Q9EPC6 name: profilin-2 (rat) def: "A profilin-2 that is encoded in the genome of rat." [OMA:Q9EPC6, PANTHER:PTHR13936:SF3, PRO:DNx] comment: Category=organism-gene. synonym: "Pfn2" RELATED Gene-based [UniProtKB:Q9EPC6] synonym: "rPFN2" EXACT PRO-short-label [PRO:DNx] synonym: "profilin II (rat)" EXACT [UniProtKB:Q9EPC6] xref: UniProtKB:Q9EPC6 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012586 ! profilin-2 relationship: has_gene_template RGD:621826 ! Pfn2 (rat) [Term] id: PR:000020938 name: profilin-2, initiator methionine removed form def: "A profilin-2 that has had the initiator methionine removed." [PRO:DNx] comment: Category=modification. synonym: "PFN2/InitMet-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000012586 ! profilin-2 intersection_of: lacks_part PR:000021937 ! initiator methionine