[Term]
id: PR:P07737-1
name: profilin-1 isoform 1 (human)
def: "A profilin-1 isoform 1 that is encoded in the genome of human." [PMID:18829504, SALO:AJ]
comment: Category=organism-sequence. Salivary oral cancer biomarker.
synonym: "hPFN1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07737-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025644 ! profilin-1 isoform 1

[Term]
id: PR:000012585
name: profilin-1
def: "A profilin that is a translation product of the human PFN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PFN1" EXACT PRO-short-label [PRO:DNx]
synonym: "profilin I" EXACT []
is_a: PR:000050050 ! profilin

[Term]
id: PR:P07737
name: profilin-1 (human)
def: "A profilin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07737]
comment: Category=organism-gene.
synonym: "PFN1" RELATED Gene-based [UniProtKB:P07737]
synonym: "hPFN1" EXACT PRO-short-label [PRO:DNx]
synonym: "profilin I (human)" EXACT [UniProtKB:P07737]
synonym: "epididymis tissue protein Li 184a (human)" EXACT [UniProtKB:P07737]
xref: UniProtKB:P07737
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012585 ! profilin-1
relationship: has_gene_template HGNC:8881 ! PFN1 (human)

[Term]
id: PR:000048752
name: profilin-1, initiator methionine removed form (human)
def: "A profilin-1 (human) that has had the initiator methionine removed. UniProtKB:P07737, 2-140." [PRO:DNx, Reactome:R-HSA-203081, Reactome:R-HSA-350755]
comment: Category=organism-modification.
synonym: "PRO_0000199571" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPFN1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07737, 2-140" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-203081 "PR:000048752 located_in GO:0005829"
xref: Reactome:R-HSA-350755 "PR:000048752 located_in GO:0005576"
xref: TDR:8592
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P07737 ! profilin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P62962
name: profilin-1 (mouse)
def: "A profilin-1 that is encoded in the genome of mouse." [OMA:P62962, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pfn1" RELATED Gene-based [UniProtKB:P62962]
synonym: "mPFN1" EXACT PRO-short-label [PRO:DNx]
synonym: "profilin I (mouse)" EXACT [UniProtKB:P62962]
xref: UniProtKB:P62962
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012585 ! profilin-1
relationship: has_gene_template MGI:97549 ! Pfn1 (mouse)

[Term]
id: PR:P62963
name: profilin-1 (rat)
def: "A profilin-1 that is encoded in the genome of rat." [OMA:P62963, PANTHER:PTHR13936:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pfn1" RELATED Gene-based [UniProtKB:P62963]
synonym: "rPFN1" EXACT PRO-short-label [PRO:DNx]
synonym: "profilin I (rat)" EXACT [UniProtKB:P62963]
xref: UniProtKB:P62963
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012585 ! profilin-1
relationship: has_gene_template RGD:621825 ! Pfn1 (rat)

[Term]
id: PR:000026622
name: profilin-1 isoform 1, initiator methionine removed form
def: "A profilin-1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "PFN1/iso:1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000025644 ! profilin-1 isoform 1

[Term]
id: PR:000025644
name: profilin-1 isoform 1
def: "A profilin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07737-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "PFN1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000012585 ! profilin-1

[Term]
id: PR:P62962-1
name: profilin-1 isoform 1 (mouse)
def: "A profilin-1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mPFN1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P62962-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000025644 ! profilin-1 isoform 1

[Term]
id: PR:000020937
name: profilin-1, initiator methionine removed form
def: "A profilin-1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "PFN1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000012585 ! profilin-1
intersection_of: lacks_part PR:000021937 ! initiator methionine