[Term]
id: PR:000012582
name: ATP-dependent 6-phosphofructokinase, liver type
def: "A Boreoeutherial-type ATP-dependent 6-phosphofructokinase that is a translation product of the human PFKL gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PFKL" EXACT PRO-short-label [PRO:DNx]
synonym: "Pfkb" RELATED Gene-based []
synonym: "PFK-B" EXACT []
synonym: "Pfk-l" RELATED Gene-based []
synonym: "phosphohexokinase" BROAD [PRO:DNx]
synonym: "phosphofructokinase 1" BROAD [PRO:DNx]
synonym: "6-phosphofructokinase type B" EXACT []
synonym: "phosphofructo-1-kinase isozyme B" EXACT []
is_a: PR:000050099 ! Boreoeutherial-type ATP-dependent 6-phosphofructokinase

[Term]
id: PR:P17858
name: ATP-dependent 6-phosphofructokinase, liver type (human)
def: "An ATP-dependent 6-phosphofructokinase, liver type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17858]
comment: Category=organism-gene.
synonym: "PFKL" RELATED Gene-based [UniProtKB:P17858]
synonym: "hPFKL" EXACT PRO-short-label [PRO:DNx]
synonym: "PFK-B (human)" EXACT [UniProtKB:P17858]
synonym: "PFK-L (human)" EXACT [UniProtKB:P17858]
synonym: "ATP-PFK (human)" BROAD [UniProtKB:P17858]
synonym: "phosphohexokinase (human)" BROAD [UniProtKB:P17858]
synonym: "6-phosphofructokinase type B (human)" EXACT [UniProtKB:P17858]
synonym: "phosphofructo-1-kinase isozyme B (human)" EXACT [UniProtKB:P17858]
xref: DTO:03100199
xref: UniProtKB:P17858
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012582 ! ATP-dependent 6-phosphofructokinase, liver type
relationship: has_gene_template HGNC:8876 ! PFKL (human)

[Term]
id: PR:000055950
name: ATP-dependent 6-phosphofructokinase, liver type N-glycosylated 1 (human)
def: "An ATP-dependent 6-phosphofructokinase, liver type (human) that has been N-glycosylated at the residue equivalent to Asn-399 of the amino acid sequence represented by UniProtKB:P17858-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P17858-1, Asn-399, MOD:00160~GNO:G00912UN." [GlyGen:P17858-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hPFKL/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17858-1, Asn-399, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P17858 ! ATP-dependent 6-phosphofructokinase, liver type (human)
relationship: has_part GNO:G00912UN ! G00912UN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P17858-2
name: ATP-dependent 6-phosphofructokinase, liver type isoform h2 (human)
def: "An ATP-dependent 6-phosphofructokinase, liver type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17858-2." [PRO:DNx, UniProtKB:P17858]
comment: Category=organism-sequence.
synonym: "hPFKL/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "ATP-dependent 6-phosphofructokinase, liver type isoform a (human)" EXACT [UniProtKB:P17858]
xref: UniProtKB:P17858-2
is_a: PR:P17858 ! ATP-dependent 6-phosphofructokinase, liver type (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P17858-1
name: ATP-dependent 6-phosphofructokinase, liver type isoform 1 (human)
def: "An ATP-dependent 6-phosphofructokinase, liver type isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hPFKL/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P17858-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026459 ! ATP-dependent 6-phosphofructokinase, liver type isoform 1

[Term]
id: PR:000027299
name: ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form (human)
def: "An ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form in human. Example: UniProtKB:P17858-1, 2-780." [PRO:DNx]
comment: Category=organism-modification.
synonym: "PRO_0000112021" NARROW PRO-proteoform-ftid [PRO:DNx]
synonym: "hPFKL/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17858-1, 2-780" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-70459 "PR:000027299 located_in GO:0005829"
xref: Reactome:R-HSA-6800876 "PR:000027299 located_in GO:0034774"
xref: Reactome:R-HSA-6801030 "PR:000027299 located_in GO:1904813"
xref: Reactome:R-HSA-6806471 "PR:000027299 located_in GO:0005576"
xref: TDR:8099
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000020936 ! ATP-dependent 6-phosphofructokinase, liver type, initiator methionine removed form