[Term]
id: PR:000012539
name: E3 ubiquitin-protein ligase pellino homolog 2
def: "A protein pellino that is a translation product of the human PELI2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PELI2" EXACT PRO-short-label [PRO:DNx]
synonym: "pellino 2" EXACT []
synonym: "pellino-2" EXACT []
synonym: "RING-type E3 ubiquitin transferase pellino homolog 2" EXACT []
is_a: PR:000003140 ! protein pellino

[Term]
id: PR:000027058
name: E3 ubiquitin-protein ligase pellino homolog 2 phosphorylated 1 (human)
def: "An E3 ubiquitin-protein ligase pellino homolog 2 phosphorylated 1 in human. This is the active form and it is phosphorylated at least in a critical Thr residue. UniProtKB:Q9HAT8, Thr-290, MOD:00047." [PMID:19264966, PRO:CNA]
comment: Category=organism-modification.
synonym: "hPELI2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9HAT8, Thr-290, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027055 ! E3 ubiquitin-protein ligase pellino homolog 2 phosphorylated 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:Q9HAT8
name: E3 ubiquitin-protein ligase pellino homolog 2 (human)
def: "An E3 ubiquitin-protein ligase pellino homolog 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9HAT8]
comment: Category=organism-gene.
synonym: "PELI2" RELATED Gene-based [UniProtKB:Q9HAT8]
synonym: "hPELI2" EXACT PRO-short-label [PRO:DNx]
synonym: "pellino-2 (human)" EXACT [UniProtKB:Q9HAT8]
synonym: "RING-type E3 ubiquitin transferase pellino homolog 2 (human)" EXACT [UniProtKB:Q9HAT8]
xref: UniProtKB:Q9HAT8
xref: Reactome:R-HSA-450694 "PR:Q9HAT8 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012539 ! E3 ubiquitin-protein ligase pellino homolog 2
relationship: has_gene_template HGNC:8828 ! PELI2 (human)

[Term]
id: PR:000048741
name: E3 ubiquitin-protein ligase pellino homolog 2 phosphorylated form (human)
def: "An E3 ubiquitin-protein ligase pellino homolog 2 (human) that includes at least one phosphorylated residue. UniProtKB:Q9HAT8, MOD:00696." [PRO:DNx, Reactome:R-HSA-450825]
comment: Category=organism-modification.
synonym: "hPELI2/PhosRes+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9HAT8, MOD:00696" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-450825 "PR:000048741 located_in GO:0005829"
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:Q9HAT8 ! E3 ubiquitin-protein ligase pellino homolog 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens