[Term]
id: PR:000012469
name: cGMP-dependent 3',5'-cyclic phosphodiesterase
def: "A GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase that is a translation product of the human PDE2A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PDE2A" EXACT PRO-short-label [PRO:DNx]
synonym: "cGSPDE" EXACT []
synonym: "CGS-PDE" EXACT []
synonym: "cyclic GMP-stimulated phosphodiesterase" EXACT []
xref: IUPHARobj:1297
is_a: PR:000050164 ! GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase

[Term]
id: PR:O00408-5
name: cGMP-dependent 3',5'-cyclic phosphodiesterase isoform h5 (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00408-5." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-sequence.
synonym: "hPDE2A/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00408-5
is_a: PR:O00408 ! cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00408-4
name: cGMP-dependent 3',5'-cyclic phosphodiesterase isoform hPDE2A4 (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00408-4." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-sequence.
synonym: "hPDE2A/iso:hPDE2A4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00408-4
is_a: PR:O00408 ! cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00408-6
name: cGMP-dependent 3',5'-cyclic phosphodiesterase isoform h6 (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00408-6." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-sequence.
synonym: "hPDE2A/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00408-6
is_a: PR:O00408 ! cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00408-1
name: cGMP-dependent 3',5'-cyclic phosphodiesterase isoform hPDE2A3 (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00408-1." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-sequence.
synonym: "hPDE2A/iso:hPDE2A3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00408-1
is_a: PR:O00408 ! cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00408-3
name: cGMP-dependent 3',5'-cyclic phosphodiesterase isoform hPDE2A2 (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00408-3." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-sequence.
synonym: "hPDE2A/iso:hPDE2A2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00408-3
is_a: PR:O00408 ! cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00408-2
name: cGMP-dependent 3',5'-cyclic phosphodiesterase isoform hPDE2A1 (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00408-2." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-sequence.
synonym: "hPDE2A/iso:hPDE2A1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00408-2
is_a: PR:O00408 ! cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00408
name: cGMP-dependent 3',5'-cyclic phosphodiesterase (human)
def: "A cGMP-dependent 3',5'-cyclic phosphodiesterase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00408]
comment: Category=organism-gene.
synonym: "PDE2A" RELATED Gene-based [UniProtKB:O00408]
synonym: "hPDE2A" EXACT PRO-short-label [PRO:DNx]
synonym: "cGSPDE (human)" EXACT [UniProtKB:O00408]
synonym: "CGS-PDE (human)" EXACT [UniProtKB:O00408]
synonym: "cyclic GMP-stimulated phosphodiesterase (human)" EXACT [UniProtKB:O00408]
xref: Reactome:R-HSA-418499 "PR:O00408 located_in GO:0005829"
xref: UniProtKB:O00408
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012469 ! cGMP-dependent 3',5'-cyclic phosphodiesterase
relationship: has_gene_template HGNC:8777 ! PDE2A (human)