[Term]
id: PR:Q53EL6
name: programmed cell death protein 4 (human)
def: "A programmed cell death protein 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q53EL6]
comment: Category=organism-gene.
synonym: "H731" RELATED Gene-based [UniProtKB:Q53EL6]
synonym: "PDCD4" RELATED Gene-based [UniProtKB:Q53EL6]
synonym: "hPDCD4" EXACT PRO-short-label [PRO:DNx]
synonym: "protein 197/15a (human)" EXACT [UniProtKB:Q53EL6]
synonym: "nuclear antigen H731-like (human)" EXACT [UniProtKB:Q53EL6]
synonym: "neoplastic transformation inhibitor protein (human)" EXACT [UniProtKB:Q53EL6]
xref: Reactome:R-HSA-5432887 "PR:Q53EL6 located_in GO:0005829"
xref: UniProtKB:Q53EL6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012455 ! programmed cell death protein 4
relationship: has_gene_template HGNC:8763 ! PDCD4 (human)

[Term]
id: PR:Q53EL6-1
name: programmed cell death protein 4 isoform 1 (human)
def: "A programmed cell death protein 4 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPDCD4/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q53EL6-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040881 ! programmed cell death protein 4 isoform 1

[Term]
id: PR:000012455
name: programmed cell death protein 4
def: "A protein that is a translation product of the human PDCD4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Ma3" RELATED Gene-based []
synonym: "Tis" RELATED Gene-based []
synonym: "H731" RELATED Gene-based []
synonym: "PDCD4" EXACT PRO-short-label [PRO:DNx]
synonym: "protein MA-3" EXACT []
synonym: "protein 197/15a" EXACT []
synonym: "nuclear antigen H731-like" EXACT []
synonym: "topoisomerase-inhibitor suppressed protein" EXACT []
synonym: "neoplastic transformation inhibitor protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q53EL6-2
name: programmed cell death protein 4 isoform h2 (human)
def: "A programmed cell death protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q53EL6-2." [PRO:DNx, UniProtKB:Q53EL6]
comment: Category=organism-sequence.
synonym: "hPDCD4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q53EL6-2
is_a: PR:Q53EL6 ! programmed cell death protein 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045967
name: programmed cell death protein 4 phosphorylated 1 (human)
def: "A programmed cell death protein 4 (human) that has been phosphorylated at the position equivalent to Ser-67 of the amino acid sequence represented by UniProtKB:Q53EL6-1. Example: UniProtKB:Q53EL6-1, Ser-67, MOD:00046." [PMID:17053147, iPTMnet:Q53EL6]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17053147). Status=unreviewed.
synonym: "hPDCD4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q53EL6-1, Ser-67, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q53EL6 ! programmed cell death protein 4 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens