[Term]
id: PR:000012339
name: propionyl-CoA carboxylase alpha chain, mitochondrial
def: "A protein that is a translation product of the human PCCA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PCCA" EXACT PRO-short-label [PRO:DNx]
synonym: "PCCase subunit alpha" EXACT []
synonym: "propanoyl-CoA:carbon dioxide ligase subunit alpha" EXACT []
xref: IUPHARobj:1266
is_a: PR:000000001 ! protein

[Term]
id: PR:P05165-1
name: propionyl-CoA carboxylase alpha chain, mitochondrial isoform h1 (human)
def: "A propionyl-CoA carboxylase alpha chain, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05165-1." [PRO:DNx, UniProtKB:P05165]
comment: Category=organism-sequence.
synonym: "hPCCA/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05165-1
is_a: PR:P05165 ! propionyl-CoA carboxylase alpha chain, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05165-3
name: propionyl-CoA carboxylase alpha chain, mitochondrial isoform h3 (human)
def: "A propionyl-CoA carboxylase alpha chain, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05165-3." [PRO:DNx, UniProtKB:P05165]
comment: Category=organism-sequence.
synonym: "hPCCA/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05165-3
is_a: PR:P05165 ! propionyl-CoA carboxylase alpha chain, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05165-2
name: propionyl-CoA carboxylase alpha chain, mitochondrial isoform h2 (human)
def: "A propionyl-CoA carboxylase alpha chain, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05165-2." [PRO:DNx, UniProtKB:P05165]
comment: Category=organism-sequence.
synonym: "hPCCA/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05165-2
is_a: PR:P05165 ! propionyl-CoA carboxylase alpha chain, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048702
name: propionyl-CoA carboxylase alpha chain, mitochondrial, transit peptide removed biotinylated 1 (human)
def: "A propionyl-CoA carboxylase alpha chain, mitochondrial (human) that has had the transit peptide removed and has been post-translationally modified to include biotinylated lysine at position 694 of the amino acid sequence represented by UniProtKB:P05165. UniProtKB:P05165, 53-728, Lys-694, MOD:00126." [PRO:DNx, Reactome:R-HSA-2993839, Reactome:R-HSA-3323186]
comment: Category=organism-modification.
synonym: "hPCCA/TransPep-/Btn:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000002837, Lys-694, MOD:00126" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P05165, 53-728, Lys-694, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2993839 "PR:000048702 located_in GO:0005759"
xref: Reactome:R-HSA-3323186 "PR:000048702 located_in GO:0005829"
is_a: PR:P05165 ! propionyl-CoA carboxylase alpha chain, mitochondrial (human)
relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000725 ! transit_peptide

[Term]
id: PR:000048701
name: propionyl-CoA carboxylase alpha chain, mitochondrial, transit peptide removed form (human)
def: "A propionyl-CoA carboxylase alpha chain, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P05165, 53-728." [PRO:DNx, Reactome:R-HSA-71021]
comment: Category=organism-modification.
synonym: "PRO_0000002837" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hPCCA/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05165, 53-728" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-71021 "PR:000048701 located_in GO:0005829"
intersection_of: PR:P05165 ! propionyl-CoA carboxylase alpha chain, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05165
name: propionyl-CoA carboxylase alpha chain, mitochondrial (human)
def: "A propionyl-CoA carboxylase alpha chain, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05165]
comment: Category=organism-gene.
synonym: "PCCA" RELATED Gene-based [UniProtKB:P05165]
synonym: "hPCCA" EXACT PRO-short-label [PRO:DNx]
synonym: "PCCase subunit alpha (human)" EXACT [UniProtKB:P05165]
synonym: "propanoyl-CoA:carbon dioxide ligase subunit alpha (human)" EXACT [UniProtKB:P05165]
xref: UniProtKB:P05165
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012339 ! propionyl-CoA carboxylase alpha chain, mitochondrial
relationship: has_gene_template HGNC:8653 ! PCCA (human)