[Term]
id: PR:Q99572
name: P2X purinoceptor 7 (human)
def: "A P2X purinoceptor 7 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-gene.
synonym: "P2RX7" RELATED Gene-based [UniProtKB:Q99572]
synonym: "hP2RX7" EXACT PRO-short-label [PRO:DNx]
synonym: "P2X7 (human)" EXACT [UniProtKB:Q99572]
synonym: "ATP receptor (human)" BROAD [UniProtKB:Q99572]
synonym: "P2Z receptor (human)" EXACT [UniProtKB:Q99572]
synonym: "purinergic receptor (human)" BROAD [UniProtKB:Q99572]
xref: UniProtKB:Q99572
xref: Reactome:R-HSA-877215 "PR:Q99572 located_in GO:0005886"
xref: DTO:01100270
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012194 ! P2X purinoceptor 7
relationship: has_gene_template HGNC:8537 ! P2RX7 (human)

[Term]
id: PR:Q99572-7
name: P2X purinoceptor 7 isoform G (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-7." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:G" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99572-7
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99572-6
name: P2X purinoceptor 7 isoform F (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-6." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:F" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99572-6
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99572-5
name: P2X purinoceptor 7 isoform E (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-5." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99572-5
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99572-4
name: P2X purinoceptor 7 isoform D (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-4." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99572-4
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99572-3
name: P2X purinoceptor 7 isoform C (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-3." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99572-3
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99572-2
name: P2X purinoceptor 7 isoform B (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-2." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:B" EXACT PRO-short-label [PRO:DNx]
synonym: "P2X purinoceptor 7 isoform Delta-C (human)" EXACT [UniProtKB:Q99572]
synonym: "P2X purinoceptor 7 isoform cytoplasmic tail deleted (human)" EXACT [UniProtKB:Q99572]
xref: UniProtKB:Q99572-2
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99572-1
name: P2X purinoceptor 7 isoform A (human)
def: "A P2X purinoceptor 7 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99572-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042714 ! P2X purinoceptor 7 isoform 1

[Term]
id: PR:000012194
name: P2X purinoceptor 7
def: "A P2X receptor protein that is a translation product of the human P2RX7 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "P2X7" EXACT []
synonym: "P2RX7" EXACT PRO-short-label [PRO:DNx]
synonym: "ATP receptor" BROAD [PRO:DNx]
synonym: "P2Z receptor" EXACT []
synonym: "purinergic receptor" BROAD [PRO:DNx]
xref: IUPHARobj:484
is_a: PR:000044669 ! P2X receptor protein

[Term]
id: PR:Q99572-8
name: P2X purinoceptor 7 isoform H (human)
def: "A P2X purinoceptor 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99572-8." [PRO:DNx, UniProtKB:Q99572]
comment: Category=organism-sequence.
synonym: "hP2RX7/iso:H" EXACT PRO-short-label [PRO:DNx]
synonym: "P2X purinoceptor 7 isoform Delta-TM1 (human)" EXACT [UniProtKB:Q99572]
xref: UniProtKB:Q99572-8
is_a: PR:Q99572 ! P2X purinoceptor 7 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens