[Term]
id: PR:Q96D31-2
name: calcium release-activated calcium channel protein 1 isoform beta (human)
def: "A calcium release-activated calcium channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96D31-2." [PRO:DNx, UniProtKB:Q96D31]
comment: Category=organism-sequence.
synonym: "hORAI1/iso:beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96D31-2
is_a: PR:Q96D31 ! calcium release-activated calcium channel protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96D31
name: calcium release-activated calcium channel protein 1 (human)
def: "A calcium release-activated calcium channel protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96D31]
comment: Category=organism-gene.
synonym: "ORAI1" RELATED Gene-based [UniProtKB:Q96D31]
synonym: "CRACM1" RELATED Gene-based [UniProtKB:Q96D31]
synonym: "hORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "TMEM142A" RELATED Gene-based [UniProtKB:Q96D31]
synonym: "protein orai-1 (human)" EXACT [UniProtKB:Q96D31]
synonym: "transmembrane protein 142A (human)" EXACT [UniProtKB:Q96D31]
xref: UniProtKB:Q96D31
xref: Reactome:R-HSA-434672 "PR:Q96D31 located_in GO:0005886"
xref: DTO:01100091
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012027 ! calcium release-activated calcium channel protein 1
relationship: has_gene_template HGNC:25896 ! ORAI1 (human)

[Term]
id: PR:000046023
name: calcium release-activated calcium channel protein 1 phosphorylated 1 (human)
def: "A calcium release-activated calcium channel protein 1 (human) that has been phosphorylated at the position equivalent to Ser-34 of the amino acid sequence represented by UniProtKB:Q96D31-1. Example: UniProtKB:Q96D31-1, Ser-34, MOD:00046." [PMID:26269433, iPTMnet:Q96D31]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26269433). Status=unreviewed.
synonym: "hORAI1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q96D31-1, Ser-34, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q96D31 ! calcium release-activated calcium channel protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96D31-1
name: calcium release-activated calcium channel protein 1 isoform alpha (human)
def: "A calcium release-activated calcium channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96D31-1." [PRO:DNx, UniProtKB:Q96D31]
comment: Category=organism-sequence.
synonym: "hORAI1/iso:alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q96D31-1
is_a: PR:Q96D31 ! calcium release-activated calcium channel protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012027
name: calcium release-activated calcium channel protein 1
def: "An orai channel protein that is a translation product of the human ORAI1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ORAI1" EXACT PRO-short-label [PRO:DNx]
synonym: "CRACM1" RELATED Gene-based []
synonym: "TMEM142A" RELATED Gene-based []
synonym: "protein orai-1" EXACT []
synonym: "transmembrane protein 142A" EXACT []
xref: IUPHARobj:2964
is_a: PR:000044626 ! orai channel protein