[Term] id: PR:000011483 name: oxidized purine nucleoside triphosphate hydrolase def: "A protein that is a translation product of the human NUDT1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "MTH1" RELATED Gene-based [] synonym: "NUDT1" EXACT PRO-short-label [PRO:DNx] synonym: "8-oxo-dGTPase" EXACT [] synonym: "nudix motif 1" EXACT [] synonym: "2-hydroxy-dATP diphosphatase" EXACT [] synonym: "7,8-dihydro-8-oxoguanine triphosphatase" EXACT [] synonym: "nucleoside diphosphate-linked moiety X motif 1" EXACT [] synonym: "methylated purine nucleoside triphosphate hydrolase" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P36639-4 name: oxidized purine nucleoside triphosphate hydrolase isoform hp18 (human) def: "An oxidized purine nucleoside triphosphate hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36639-4." [PRO:DNx, UniProtKB:P36639] comment: Category=organism-sequence. synonym: "hNUDT1/iso:hp18" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P36639-4 is_a: PR:P36639 ! oxidized purine nucleoside triphosphate hydrolase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P36639-3 name: oxidized purine nucleoside triphosphate hydrolase isoform hp21 (human) def: "An oxidized purine nucleoside triphosphate hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36639-3." [PRO:DNx, UniProtKB:P36639] comment: Category=organism-sequence. synonym: "hNUDT1/iso:hp21" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P36639-3 is_a: PR:P36639 ! oxidized purine nucleoside triphosphate hydrolase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P36639-2 name: oxidized purine nucleoside triphosphate hydrolase isoform hp22 (human) def: "An oxidized purine nucleoside triphosphate hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36639-2." [PRO:DNx, UniProtKB:P36639] comment: Category=organism-sequence. synonym: "hNUDT1/iso:hp22" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P36639-2 is_a: PR:P36639 ! oxidized purine nucleoside triphosphate hydrolase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P36639-1 name: oxidized purine nucleoside triphosphate hydrolase isoform hp26 (human) def: "An oxidized purine nucleoside triphosphate hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36639-1." [PRO:DNx, UniProtKB:P36639] comment: Category=organism-sequence. synonym: "hNUDT1/iso:hp26" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P36639-1 xref: Reactome:R-HSA-2395812 "PR:P36639-1 located_in GO:0005829" is_a: PR:P36639 ! oxidized purine nucleoside triphosphate hydrolase (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P36639 name: oxidized purine nucleoside triphosphate hydrolase (human) def: "An oxidized purine nucleoside triphosphate hydrolase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P36639] comment: Category=organism-gene. synonym: "MTH1" RELATED Gene-based [UniProtKB:P36639] synonym: "NUDT1" RELATED Gene-based [UniProtKB:P36639] synonym: "hNUDT1" EXACT PRO-short-label [PRO:DNx] synonym: "8-oxo-dGTPase (human)" EXACT [UniProtKB:P36639] synonym: "nudix motif 1 (human)" EXACT [UniProtKB:P36639] synonym: "2-hydroxy-dATP diphosphatase (human)" EXACT [UniProtKB:P36639] synonym: "7,8-dihydro-8-oxoguanine triphosphatase (human)" EXACT [UniProtKB:P36639] synonym: "nucleoside diphosphate-linked moiety X motif 1 (human)" EXACT [UniProtKB:P36639] synonym: "methylated purine nucleoside triphosphate hydrolase (human)" EXACT [UniProtKB:P36639] xref: UniProtKB:P36639 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000011483 ! oxidized purine nucleoside triphosphate hydrolase relationship: has_gene_template HGNC:8048 ! NUDT1 (human)