[Term]
id: PR:000011450
name: RNA cytosine C(5)-methyltransferase NSUN2
def: "A protein that is a translation product of the human NSUN2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Misu" RELATED Gene-based []
synonym: "SAKI" RELATED Gene-based []
synonym: "TRM4" RELATED Gene-based []
synonym: "NSUN2" EXACT PRO-short-label [PRO:DNx]
synonym: "D13Wsu123e" RELATED Gene-based []
synonym: "tRNA methyltransferase 4 homolog" EXACT []
synonym: "substrate of AIM1/Aurora kinase B" EXACT []
synonym: "NOL1/NOP2/Sun domain family member 2" EXACT []
synonym: "mRNA cytosine C(5)-methyltransferase" EXACT []
synonym: "tRNA cytosine C(5)-methyltransferase" EXACT []
synonym: "Myc-induced SUN domain-containing protein" EXACT []
synonym: "tRNA (cytosine(34)-C(5))-methyltransferase" EXACT []
synonym: "tRNA (cytosine-5-)-methyltransferase NSUN2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q5ZLV4
name: RNA cytosine-C(5)-methyltransferase NSUN2 (chicken)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 that is encoded in the genome of chicken." [OMA:Q5ZLV4, PANTHER:PTHR22808:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "NSUN2" RELATED Gene-based [UniProtKB:Q5ZLV4]
synonym: "chick-NSUN2" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_4l11" RELATED Gene-based [UniProtKB:Q5ZLV4]
synonym: "NOL1/NOP2/Sun domain family member 2 (chicken)" EXACT [UniProtKB:Q5ZLV4]
synonym: "mRNA cytosine C(5)-methyltransferase (chicken)" EXACT [UniProtKB:Q5ZLV4]
synonym: "tRNA cytosine C(5)-methyltransferase (chicken)" EXACT [UniProtKB:Q5ZLV4]
xref: UniProtKB:Q5ZLV4
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000011450 ! RNA cytosine C(5)-methyltransferase NSUN2
relationship: has_gene_template NCBIGene:420938 ! NSUN2 (chicken)

[Term]
id: PR:Q1HFZ0
name: RNA cytosine C(5)-methyltransferase NSUN2 (mouse)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 that is encoded in the genome of mouse." [OMA:Q1HFZ0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Misu" RELATED Gene-based [UniProtKB:Q1HFZ0]
synonym: "Nsun2" RELATED Gene-based [UniProtKB:Q1HFZ0]
synonym: "mNSUN2" EXACT PRO-short-label [PRO:DNx]
synonym: "D13Wsu123e" RELATED Gene-based [UniProtKB:Q1HFZ0]
synonym: "NOL1/NOP2/Sun domain family member 2 (mouse)" EXACT [UniProtKB:Q1HFZ0]
synonym: "mRNA cytosine C(5)-methyltransferase (mouse)" EXACT [UniProtKB:Q1HFZ0]
synonym: "tRNA cytosine C(5)-methyltransferase (mouse)" EXACT [UniProtKB:Q1HFZ0]
synonym: "Myc-induced SUN domain-containing protein (mouse)" EXACT [UniProtKB:Q1HFZ0]
xref: UniProtKB:Q1HFZ0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011450 ! RNA cytosine C(5)-methyltransferase NSUN2
relationship: has_gene_template MGI:107252 ! Nsun2 (mouse)

[Term]
id: PR:P38205
name: multisite-specific tRNA:(cytosine-C(5))-methyltransferase (yeast)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 that is encoded in the genome of yeast." [OMA:P38205, PANTHER:PTHR22808:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "NCL1" RELATED Gene-based [UniProtKB:P38205]
synonym: "TRM4" RELATED Gene-based [UniProtKB:P38205]
synonym: "yNSUN2" EXACT PRO-short-label [PRO:DNx]
synonym: "YBL024W" RELATED Gene-based [UniProtKB:P38205]
synonym: "YBL0437" RELATED Gene-based [UniProtKB:P38205]
synonym: "tRNA methyltransferase 4 (yeast)" EXACT [UniProtKB:P38205]
synonym: "tRNA (cytosine-5-)-methyltransferase NCL1 (yeast)" EXACT [UniProtKB:P38205]
synonym: "multisite-specific tRNA:m5C-methyltransferase (yeast)" EXACT [UniProtKB:P38205]
xref: UniProtKB:P38205
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000011450 ! RNA cytosine C(5)-methyltransferase NSUN2
relationship: has_gene_template SGD:S000000120 ! NCL1 (yeast)

[Term]
id: PR:Q1HFZ0-2
name: RNA cytosine C(5)-methyltransferase NSUN2 isoform m2 (mouse)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1HFZ0-2." [PRO:DNx, UniProtKB:Q1HFZ0]
comment: Category=organism-sequence.
synonym: "mNSUN2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q1HFZ0-2
is_a: PR:Q1HFZ0 ! RNA cytosine C(5)-methyltransferase NSUN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q08J23
name: RNA cytosine C(5)-methyltransferase NSUN2 (human)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q08J23]
comment: Category=organism-gene.
synonym: "SAKI" RELATED Gene-based [UniProtKB:Q08J23]
synonym: "TRM4" RELATED Gene-based [UniProtKB:Q08J23]
synonym: "NSUN2" RELATED Gene-based [UniProtKB:Q08J23]
synonym: "hTrm4" EXACT [UniProtKB:Q08J23]
synonym: "hNSUN2" EXACT PRO-short-label [PRO:DNx]
synonym: "Misu (human)" EXACT [UniProtKB:Q08J23]
synonym: "tRNA methyltransferase 4 homolog (human)" EXACT [UniProtKB:Q08J23]
synonym: "substrate of AIM1/Aurora kinase B (human)" EXACT [UniProtKB:Q08J23]
synonym: "NOL1/NOP2/Sun domain family member 2 (human)" EXACT [UniProtKB:Q08J23]
synonym: "mRNA cytosine C(5)-methyltransferase (human)" EXACT [UniProtKB:Q08J23]
synonym: "tRNA cytosine C(5)-methyltransferase (human)" EXACT [UniProtKB:Q08J23]
synonym: "Myc-induced SUN domain-containing protein (human)" EXACT [UniProtKB:Q08J23]
xref: Reactome:R-HSA-6782382 "PR:Q08J23 located_in GO:0005654"
xref: UniProtKB:Q08J23
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011450 ! RNA cytosine C(5)-methyltransferase NSUN2
relationship: has_gene_template HGNC:25994 ! NSUN2 (human)

[Term]
id: PR:Q1HFZ0-1
name: RNA cytosine C(5)-methyltransferase NSUN2 isoform m1 (mouse)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1HFZ0-1." [PRO:DNx, UniProtKB:Q1HFZ0]
comment: Category=organism-sequence.
synonym: "mNSUN2/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q1HFZ0-1
is_a: PR:Q1HFZ0 ! RNA cytosine C(5)-methyltransferase NSUN2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9W4M9
name: tRNA (cytosine(34)-C(5))-methyltransferase (fruit fly)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 that is encoded in the genome of fruit fly." [OMA:Q9W4M9, PANTHER:PTHR22808:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nsun2" RELATED Gene-based [UniProtKB:Q9W4M9]
synonym: "CG6133" RELATED Gene-based [UniProtKB:Q9W4M9]
synonym: "fly-NSUN2" EXACT PRO-short-label [PRO:DNx]
synonym: "NOP2/Sun domain family member 2 ortholog (fruit fly)" EXACT [UniProtKB:Q9W4M9]
xref: UniProtKB:Q9W4M9
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000011450 ! RNA cytosine C(5)-methyltransferase NSUN2
relationship: has_gene_template FlyBase:FBgn0026079 ! Nsun2 (fruit fly)

[Term]
id: PR:Q08J23-1
name: RNA cytosine C(5)-methyltransferase NSUN2 isoform h1 (human)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08J23-1." [PRO:DNx, UniProtKB:Q08J23]
comment: Category=organism-sequence.
synonym: "hNSUN2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q08J23-1
is_a: PR:Q08J23 ! RNA cytosine C(5)-methyltransferase NSUN2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q08J23-2
name: RNA cytosine C(5)-methyltransferase NSUN2 isoform h2 (human)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08J23-2." [PRO:DNx, UniProtKB:Q08J23]
comment: Category=organism-sequence.
synonym: "hNSUN2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q08J23-2
is_a: PR:Q08J23 ! RNA cytosine C(5)-methyltransferase NSUN2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q08J23-3
name: RNA cytosine C(5)-methyltransferase NSUN2 isoform h3 (human)
def: "An RNA cytosine C(5)-methyltransferase NSUN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08J23-3." [PRO:DNx, UniProtKB:Q08J23]
comment: Category=organism-sequence.
synonym: "hNSUN2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q08J23-3
is_a: PR:Q08J23 ! RNA cytosine C(5)-methyltransferase NSUN2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens