[Term]
id: PR:P00491
name: purine nucleoside phosphorylase (human)
def: "A purine nucleoside phosphorylase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00491]
comment: Category=organism-gene.
synonym: "NP" RELATED Gene-based [UniProtKB:P00491]
synonym: "PNP" RELATED Gene-based [UniProtKB:P00491]
synonym: "hPNP" EXACT PRO-short-label [PRO:DNx]
synonym: "inosine phosphorylase (human)" EXACT [UniProtKB:P00491]
synonym: "inosine-guanosine phosphorylase (human)" EXACT [UniProtKB:P00491]
xref: Reactome:R-HSA-61933 "PR:P00491 located_in GO:0005829"
xref: Reactome:R-HSA-6803278 "PR:P00491 located_in GO:1904813"
xref: Reactome:R-HSA-6803318 "PR:P00491 located_in GO:0034774"
xref: Reactome:R-HSA-6806505 "PR:P00491 located_in GO:0005576"
xref: UniProtKB:P00491
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011344 ! purine nucleoside phosphorylase
relationship: has_gene_template HGNC:7892 ! PNP (human)

[Term]
id: PR:000011344
name: purine nucleoside phosphorylase
def: "A protein that is a translation product of the human PNP gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NP" RELATED Gene-based []
synonym: "PNP" EXACT PRO-short-label [PRO:DNx]
synonym: "Pnp1" RELATED Gene-based []
synonym: "inosine phosphorylase" EXACT []
synonym: "inosine-guanosine phosphorylase" EXACT []
xref: IUPHARobj:2841
is_a: PR:000000001 ! protein

[Term]
id: PR:000036327
name: purine nucleoside phosphorylase acetylated 1 (human)
def: "A purine nucleoside phosphorylase that is N-terminal Met acetylated in human. UniProtKB:P00491, Met-1, MOD:00058." [TDR:2579]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hPNP/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P00491, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:2579
is_a: PR:000011344 ! purine nucleoside phosphorylase
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens