[Term]
id: PR:000011335
name: neurogenic locus notch homolog protein 4
def: "A NOTCH protein that is a translation product of the human NOTCH4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "INT3" RELATED Gene-based []
synonym: "Int-3" RELATED Gene-based []
synonym: "NOTCH4" EXACT PRO-short-label [PRO:DNx]
synonym: "notch 4" EXACT []
synonym: "neurogenic locus notch protein 4" EXACT []
xref: IUPHARobj:2862
is_a: PR:000050044 ! NOTCH protein

[Term]
id: PR:000057929
name: neurogenic locus notch homolog protein 4 O-glycosylated 3 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that has been O-glycosylated at the residue equivalent to Ser-95 of the amino acid sequence represented by UniProtKB:Q99466-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q99466-1, Ser-95, MOD:00002~GNO:G53434XO." [GlyGen:Q99466-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hNOTCH4/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99466-1, Ser-95, MOD:00002~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: has_part GNO:G53434XO ! G53434XO
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000057928
name: neurogenic locus notch homolog protein 4 O-glycosylated 2 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that has been O-glycosylated at the residue equivalent to Ser-93 of the amino acid sequence represented by UniProtKB:Q99466-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q99466-1, Ser-93, MOD:00002~GNO:G58001LT." [GlyGen:Q99466-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hNOTCH4/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99466-1, Ser-93, MOD:00002~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: has_part GNO:G58001LT ! G58001LT
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q6MG89
name: notch homolog 4, [Drosophila] (rat)
def: "A neurogenic locus notch homolog protein 4 that is encoded in the genome of rat." [OMA:Q6MG89, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ng5" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "Tnx" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "Ager" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "Rnf5" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "Btnl6" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "rNOTCH4" EXACT PRO-short-label [PRO:DNx]
synonym: "Stk19-ps" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "rCG_38227" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "Cyp21a1-ps" RELATED Gene-based [UniProtKB:Q6MG89]
synonym: "protein Notch4 (rat)" EXACT [UniProtKB:Q6MG89]
synonym: "notch homolog 4, isoform CRA_b (rat)" EXACT [UniProtKB:Q6MG89]
xref: UniProtKB:Q6MG89
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000011335 ! neurogenic locus notch homolog protein 4
relationship: has_gene_template RGD:1303282 ! Notch4 (rat)

[Term]
id: PR:000048625
name: neurogenic locus notch homolog protein 4, signal peptide removed form (human)
def: "A neurogenic locus notch homolog protein 4 (human) that has had the signal peptide removed. UniProtKB:Q99466, 24-2003." [PRO:DNx, Reactome:R-HSA-157121]
comment: Category=organism-modification.
synonym: "PRO_0000007701" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hNOTCH4/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99466, 24-2003" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-157121 "PR:000048625 located_in GO:0005789"
intersection_of: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000057930
name: neurogenic locus notch homolog protein 4 O-glycosylated 4 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that has been O-glycosylated at the residue equivalent to Ser-95 of the amino acid sequence represented by UniProtKB:Q99466-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q99466-1, Ser-95, MOD:00002~GNO:G58001LT." [GlyGen:Q99466-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hNOTCH4/OGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99466-1, Ser-95, MOD:00002~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: has_part GNO:G58001LT ! G58001LT
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000057927
name: neurogenic locus notch homolog protein 4 O-glycosylated 1 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that has been O-glycosylated at the residue equivalent to Ser-93 of the amino acid sequence represented by UniProtKB:Q99466-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q99466-1, Ser-93, MOD:00002~GNO:G53434XO." [GlyGen:Q99466-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hNOTCH4/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q99466-1, Ser-93, MOD:00002~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: has_part GNO:G53434XO ! G53434XO
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31695
name: neurogenic locus notch homolog protein 4 (mouse)
def: "A neurogenic locus notch homolog protein 4 that is encoded in the genome of mouse." [OMA:P31695, PRO:DNx]
comment: Category=organism-gene.
synonym: "Int3" RELATED Gene-based [UniProtKB:P31695]
synonym: "Int-3" RELATED Gene-based [UniProtKB:P31695]
synonym: "Notch4" RELATED Gene-based [UniProtKB:P31695]
synonym: "mNOTCH4" EXACT PRO-short-label [PRO:DNx]
synonym: "notch 4 (mouse)" EXACT [UniProtKB:P31695]
xref: UniProtKB:P31695
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011335 ! neurogenic locus notch homolog protein 4
relationship: has_gene_template MGI:107471 ! Notch4 (mouse)

[Term]
id: PR:Q99466
name: neurogenic locus notch homolog protein 4 (human)
def: "A neurogenic locus notch homolog protein 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99466]
comment: Category=organism-gene.
synonym: "INT3" RELATED Gene-based [UniProtKB:Q99466]
synonym: "NOTCH4" RELATED Gene-based [UniProtKB:Q99466]
synonym: "hNOTCH4" EXACT PRO-short-label [PRO:DNx]
synonym: "hNotch4" EXACT [UniProtKB:Q99466]
synonym: "notch 4 (human)" EXACT [UniProtKB:Q99466]
xref: UniProtKB:Q99466
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011335 ! neurogenic locus notch homolog protein 4
relationship: has_gene_template HGNC:7884 ! NOTCH4 (human)

[Term]
id: PR:000020766
name: neurogenic locus notch homolog protein 4 proteolytic cleavage product
def: "A neurogenic locus notch homolog protein 4 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "NOTCH4/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000011335 ! neurogenic locus notch homolog protein 4

[Term]
id: PR:Q99466-3
name: neurogenic locus notch homolog protein 4 isoform h3 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99466-3." [PRO:DNx, UniProtKB:Q99466]
comment: Category=organism-sequence.
synonym: "hNOTCH4/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99466-3
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q99466-2
name: neurogenic locus notch homolog protein 4 isoform h2 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99466-2." [PRO:DNx, UniProtKB:Q99466]
comment: Category=organism-sequence.
synonym: "hNOTCH4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99466-2
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P14585
name: protein lin-12 (worm)
def: "A neurogenic locus notch homolog protein 4 that is encoded in the genome of worm." [OMA:P14585, PRO:DNx]
comment: Category=organism-gene.
synonym: "R107.8" RELATED Gene-based [UniProtKB:P14585]
synonym: "lin-12" RELATED Gene-based [UniProtKB:P14585]
synonym: "NOTCH4 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "notch-like protein lin-12 (worm)" EXACT [UniProtKB:P14585]
synonym: "abnormal cell lineage protein 12 (worm)" EXACT [UniProtKB:P14585]
xref: UniProtKB:P14585
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000011335 ! neurogenic locus notch homolog protein 4
relationship: has_gene_template WormBase:WBGene00003001 ! lin-12 (worm)

[Term]
id: PR:Q99466-1
name: neurogenic locus notch homolog protein 4 isoform h1 (human)
def: "A neurogenic locus notch homolog protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99466-1." [PRO:DNx, UniProtKB:Q99466]
comment: Category=organism-sequence.
synonym: "hNOTCH4/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99466-1
is_a: PR:Q99466 ! neurogenic locus notch homolog protein 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q54YG2
name: extracellular matrix protein A (Dictyostelium discoideum)
def: "A neurogenic locus notch homolog protein 4 that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Dd63" RELATED Gene-based [UniProtKB:Q54YG2]
synonym: "ecmA" RELATED Gene-based [UniProtKB:Q54YG2]
synonym: "DDB_G0277853" RELATED Gene-based [UniProtKB:Q54YG2]
synonym: "Dicty-NOTCH4" EXACT PRO-short-label [PRO:DNx]
synonym: "extracellular matrix protein ST430 (Dictyostelium discoideum)" EXACT [UniProtKB:Q54YG2]
xref: UniProtKB:Q54YG2
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000011335 ! neurogenic locus notch homolog protein 4
relationship: has_gene_template dictyBase:DDB_G0277853 ! ecmA (Dictyostelium discoideum)