[Term]
id: PR:Q9H9Q4
name: non-homologous end-joining factor 1 (human)
def: "A non-homologous end-joining factor 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H9Q4]
comment: Category=organism-gene.
synonym: "XLF" RELATED Gene-based [UniProtKB:Q9H9Q4]
synonym: "NHEJ1" RELATED Gene-based [UniProtKB:Q9H9Q4]
synonym: "hNHEJ1" EXACT PRO-short-label [PRO:DNx]
synonym: "XRCC4-like factor (human)" EXACT [UniProtKB:Q9H9Q4]
synonym: "protein cernunnos (human)" EXACT [UniProtKB:Q9H9Q4]
xref: UniProtKB:Q9H9Q4
xref: Reactome:R-HSA-5687247 "PR:Q9H9Q4 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011199 ! non-homologous end-joining factor 1
relationship: has_gene_template HGNC:25737 ! NHEJ1 (human)

[Term]
id: PR:Q9H9Q4-2
name: non-homologous end-joining factor 1 isoform h2 (human)
def: "A non-homologous end-joining factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H9Q4-2." [PRO:DNx, UniProtKB:Q9H9Q4]
comment: Category=organism-sequence.
synonym: "hNHEJ1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H9Q4-2
is_a: PR:Q9H9Q4 ! non-homologous end-joining factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000011199
name: non-homologous end-joining factor 1
def: "A protein that is a translation product of the human NHEJ1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "XLF" RELATED Gene-based []
synonym: "NHEJ1" EXACT PRO-short-label [PRO:DNx]
synonym: "XRCC4-like factor" EXACT []
synonym: "protein cernunnos" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000046062
name: non-homologous end-joining factor 1 phosphorylated 1 (human)
def: "A non-homologous end-joining factor 1 (human) that has been phosphorylated at the position equivalent to Thr-181 of the amino acid sequence represented by UniProtKB:Q9H9Q4-1. Example: UniProtKB:Q9H9Q4-1, Thr-181, MOD:00047." [PMID:25661488, iPTMnet:Q9H9Q4]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:25661488). Status=unreviewed.
synonym: "hNHEJ1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9H9Q4-1, Thr-181, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9H9Q4 ! non-homologous end-joining factor 1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H9Q4-1
name: non-homologous end-joining factor 1 isoform h1 (human)
def: "A non-homologous end-joining factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H9Q4-1." [PRO:DNx, UniProtKB:Q9H9Q4]
comment: Category=organism-sequence.
synonym: "hNHEJ1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H9Q4-1
is_a: PR:Q9H9Q4 ! non-homologous end-joining factor 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens